Search Results - "ARAI, Yoshikazu"
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DNA methylation ambiguity in the Fibrillin-1 (FBN1) CpG island shore possibly involved in Marfan syndrome
Published in Scientific reports (24-03-2020)“…Fibrillin-1 ( FBN1 ) is responsible for haploinsufficient and autosomal dominant Marfan syndrome. Even in the same Marfan pedigree, penetrance and expressivity…”
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Identification of an epigenetic signature in human induced pluripotent stem cells using a linear machine learning model
Published in Human cell : official journal of Human Cell Research Society (01-01-2021)“…The use of human induced pluripotent stem cells (iPSCs), used as an alternative to human embryonic stem cells (ESCs), is a potential solution to challenges,…”
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Epigenetic mutagen-like environmental chemicals alter neural differentiation of human induced pluripotent stem cells
Published in Journal of toxicological sciences (2023)“…Various chemicals, including pesticides, heavy metals, and metabolites of tobacco, have been detected in fetal environment. Fetuses are exposed to these…”
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Design and construction of a two-degree-of-freedom linear encoder for nanometric measurement of stage position and straightness
Published in Precision engineering (2010)“…This paper presents a two-degree-of-freedom (two-DOF) linear encoder which can measure the position along the moving axis ( X-axis) and the straightness along…”
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Dog Steroidogenic Factor-1: Molecular cloning and analysis of epigenetic regulation
Published in Journal of Veterinary Medical Science (2020)“…Steroidogenic factor 1 (SF-1) is a nuclear receptor that is important in steroid hormone production, and adrenal and gonad development. The SF-1 gene is highly…”
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Generation of naive-like porcine-induced pluripotent stem cells capable of contributing to embryonic and fetal development
Published in Stem cells and development (01-02-2013)“…In pluripotent stem cells (PSCs), there are 2 types: naive and primed. Only the naive type has the capacity for producing chimeric offspring. Mouse PSCs are…”
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Generation of interleukin-2 receptor gamma gene knockout pigs from somatic cells genetically modified by zinc finger nuclease-encoding mRNA
Published in PloS one (09-10-2013)“…Zinc finger nuclease (ZFN) is a powerful tool for genome editing. ZFN-encoding plasmid DNA expression systems have been recently employed for the generation of…”
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TIF1β regulates the pluripotency of embryonic stem cells in a phosphorylation-dependent manner
Published in Proceedings of the National Academy of Sciences - PNAS (15-06-2010)“…Transcription networks composed of various transcriptional factors specifically expressed in undifferentiated embryonic stem (ES) cells have been implicated in…”
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Bit rate improvement of spatially seamless local communication system using signal multiplexing technique
Published in Electronics and communications in Japan (01-10-2020)“…In recent years, application of multiple robot system for a large scale system, such as a smart factory, is expected. A system consisting of heterogeneous…”
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Variation of DNA methylation on the IRX1/2 genes is responsible for the neural differentiation propensity in human induced pluripotent stem cells
Published in Regenerative therapy (01-12-2022)“…Human induced pluripotent stem cells (hiPSCs) are useful tools for reproducing neural development in vitro. However, each hiPSC line has a different ability to…”
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Ultra-Deep Bisulfite Sequencing to Detect Specific DNA Methylation Patterns of Minor Cell Types in Heterogeneous Cell Populations: An Example of the Pituitary Tissue
Published in PloS one (11-01-2016)“…DNA methylation is an epigenetic modification important for cell fate determination and cell type-specific gene expression. Transcriptional regulatory regions…”
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Cerebral hyperperfusion syndrome resulting in subarachnoid hemorrhage after carotid artery stenting
Published in Annals of nuclear medicine (01-11-2016)“…A 64-year-old, right-handed man underwent endovascular treatment for internal carotid artery stenosis after experiencing a left-hemispheric transient ischemic…”
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13
Detection of three-axis angles by an optical sensor
Published in Sensors and actuators. A. Physical. (25-03-2009)“…This article describes an optical method for measurement of three-axis angles (roll angle Δ θ X , pitch angle Δ θ Y , yaw angle Δ θ Z ). The laser…”
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Evidence of exposure to chemicals and heavy metals during pregnancy in Japanese women
Published in Reproductive medicine and biology (01-10-2017)“…Purpose Prenatal exposure to environmental chemicals is a growing concern, because such exposures have been shown to be associated with various diseases. The…”
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DNA hypermethylation enhanced telomerase reverse transcriptase expression in human-induced pluripotent stem cells
Published in Human cell : official journal of Human Cell Research Society (01-01-2018)“…During reprogramming into human induced pluripotent stem cells (iPSCs), several stem cell marker genes are induced, such as OCT - 4 , NANOG , SALL4 , and TERT…”
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Development of Spatially Seamless Local Communication System Based on Time Sharing Communication Strategy
Published in Journal of robotics and mechatronics (01-02-2018)“…For multiple robots to achieve complex tasks while cooperating autonomously, communication among those robots is indispensable. We have developed a local…”
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Epigenetic-scale comparison of human iPSCs generated by retrovirus, Sendai virus or episomal vectors
Published in Regenerative therapy (01-12-2018)“…Human induced pluripotent stem cells (iPSCs) are established by introducing several reprogramming factors, such as OCT3/4, SOX2, KLF4, c-MYC. Because of their…”
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Intravascular large B-cell lymphoma with cerebral infarction: a report of a difficult-to-diagnose case caused by a thrombus in the auricle of the left atrium
Published in Japanese Journal of Stroke (2023)“…Intravascular large B-cell lymphoma (IVLBCL) is a disease in which lymphoma proliferates within vessels and is characterized by anemia, hypoalbuminemia, and…”
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A linear-rotary stage for precision positioning
Published in Precision engineering (01-04-2010)“…This paper presents a linear-rotary ( Z– θ Z ) stage that can generate motions along and about the Z-axis based on friction drive. The moving element, which is…”
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Iridium-catalyzed consecutive and enantioselective [2+2+2] cycloaddition of tetraynes and hexaynes for the construction of an axially chiral biaryl system
Published in Tetrahedron (01-01-2008)“…A chiral iridium complex catalyzed a consecutive and enantioselective [2+2+2] cycloaddition of polyynes to give axially chiral compounds. Intermolecular…”
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