Search Results - "APPLEYARD, Caroline B"
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Colonic macrophage polarization in homeostasis, inflammation, and cancer
Published in American journal of physiology: Gastrointestinal and liver physiology (01-07-2016)“…Our review focuses on the colonic macrophage, a monocyte-derived, tissue-resident macrophage, and the role it plays in health and disease, specifically in…”
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2
Beyond depression and anxiety; a systematic review about the role of corticotropin-releasing hormone antagonists in diseases of the pelvic and abdominal organs
Published in PloS one (11-03-2022)“…Evidence for beneficial effects of corticotropin releasing hormone (CRH) antagonists in abdominal and pelvic organs is emerging in preclinical studies…”
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Antagonizing the corticotropin releasing hormone receptor 1 with antalarmin reduces the progression of endometriosis
Published in PloS one (14-11-2018)“…Endometriosis is a disorder in which endometrial tissue is found outside the uterus causing pain, infertility and stress. Finding effective, non-hormonal and…”
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4
Efficacy of an environmental enrichment intervention for endometriosis: a pilot study
Published in Frontiers in psychology (10-10-2023)“…We have previously shown that Environmental Enrichment (EE), a multi-modal psychosocial intervention consisting of increased social interaction, novelty, and…”
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5
Infusion of HIV-1 Nef-expressing astrocytes into the rat hippocampus induces enteropathy and interstitial pneumonitis and increases blood-brain-barrier permeability
Published in PloS one (27-11-2019)“…Even though HIV-1 replication can be suppressed by combination antiretroviral therapy (cART) inflammatory processes still occur, contributing to comorbidities…”
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Metabolomics in endometriosis: challenges and perspectives for future studies
Published in Reproduction & fertility (01-04-2021)“…Endometriosis is a complex disease characterized by inflammation and the growth of endometrial- like glands and stroma outside the uterine cavity. The…”
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Short treatment with antalarmin alters adrenal gland receptors in the rat model of endometriosis
Published in PloS one (14-01-2020)“…Endometriosis is a chronic inflammatory disorder in which endometrial tissue is found outside the uterine cavity. Previous reports suggest that there is a…”
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Serum vitamin D and colonic vitamin D receptor in inflammatory bowel disease
Published in World journal of gastroenterology : WJG (07-04-2016)“…AIM: To determine serum vitamin D levels and colonic vitamin D receptor(VDR) expression in inflammatory bowel disease(IBD) and non-IBD patients and correlate…”
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9
Double immunofluorescent staining of rat macrophages in formalin-fixed paraffin-embedded tissue using two monoclonal mouse antibodies
Published in Histochemistry and cell biology (01-12-2015)“…The conventional approach of double immunostaining to visualize more than one protein in tissues or cells using antibodies from two different host species is…”
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Stress exacerbates endometriosis manifestations and inflammatory parameters in an animal model
Published in Reproductive sciences (Thousand Oaks, Calif.) (01-08-2012)“…Women with endometriosis have significant emotional distress; however, the contribution of stress to the pathophysiology of this disease is unclear. We used a…”
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A one month high fat diet disrupts the gut microbiome and integrity of the colon inducing adiposity and behavioral despair in male Sprague Dawley rats
Published in Heliyon (01-11-2022)“…High-fat diet (HFD) is associated with gut microbiome dysfunction and mental disorders. However, the time-dependence as to when this occurs is unclear. We…”
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Molecular profiling of experimental endometriosis identified gene expression patterns in common with human disease
Published in Fertility and sterility (01-05-2007)“…Objective To validate a rat model of endometriosis using complimentary DNA (cDNA) microarrays by identifying common gene expression patterns between…”
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Feasibility and acceptability of an adapted environmental enrichment intervention for endometriosis: A pilot study
Published in Frontiers in Global Women's Health (04-01-2023)“…We have previously shown that Environmental Enrichment (EE)-consisting of social support, novelty, and open spaces-decreased disease progression and anxiety in…”
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14
Immunohistochemical expression of SP-NK-1R-EGFR pathway and VDR in colonic inflammation and neoplasia
Published in World journal of gastroenterology : WJG (14-02-2015)“…AIM:To determine the expression of neurokinin-1receptor(NK-1R),phosphorylated epidermal growth factor receptor(p EGFR),cyclooxygenase-2(Cox-2),and vitamin D…”
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Voluntary Wheel Running Reduces Vesicle Development in an Endometriosis Animal Model Through Modulation of Immune Parameters
Published in Frontiers in reproductive health (2021)“…Endometriosis is a chronic gynecological disorder characterized by the growth of endometrial glands and stroma outside the endometrial cavity producing…”
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Erlotinib inhibits progression to dysplasia in a colitis-associated colon cancer model
Published in World journal of gastroenterology : WJG (28-11-2011)“…AIM:To investigate the role of epidermal growth factor receptor(EGFR) in colitis-associated dysplasia using the EGFR tyrosine kinase inhibitor…”
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17
An angiotensin II receptor antagonist reduces inflammatory parameters in two models of colitis
Published in Regulatory peptides (07-02-2008)“…Little is known about the effects of the pro-inflammatory hormone Angiotensin II (Ang II) in inflammatory bowel disease. The aim of this study was to evaluate…”
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The Link Between Stress and Endometriosis: from Animal Models to the Clinical Scenario
Published in Reproductive sciences (Thousand Oaks, Calif.) (01-09-2020)“…There is strong evidence from humans and animal models showing that abnormal functioning of the hypothalamic-pituitary-adrenal (HPA) axis and/or the…”
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Role of tumor necrosis factor receptors in an animal model of acute colitis
Published in Cytokine (Philadelphia, Pa.) (21-10-2005)“…TNF-alpha is known to play an important role in inflammatory bowel disease (IBD); however, the pathophysiological role of its receptors is still under study…”
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Endometriosis Induces Colonic Inflammation and Reactive Gliosis in an Animal Model
Published in The FASEB journal (01-05-2022)“…Introduction Endometriosis is a complex gynecological disorder characterized by the ectopic growth of endometrial tissue. Symptoms of endometriosis are known…”
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