Search Results - "APPEL, J. Z"

Chronic Aspiration of Gastric Fluid Induces the Development of Obliterative Bronchiolitis in Rat Lung Transplants by Li, B., Hartwig, M. G, Appel, J. Z., Bush, E. L., Balsara, K. R., Holzknecht, Z. E., Collins, B. H., Howell, D. N., Parker, W., Lin, S. S., Davis, R. D.

“…Long‐term survival of a pulmonary allograft is currently hampered by obliterative bronchiolitis (OB), a form of chronic rejection that is unique to lung…”
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Leukocyte-Endothelium Interaction During the Early Stages of Hypercholesterolemia in the Rabbit: Role of P-Selectin, ICAM-1, and VCAM-1 by Scalia, Rosario, Appel, James Z, Lefer, Allan M

“…The early effects of hypercholesterolemia on leukocyte-endothelium interaction were studied in vivo in the rabbit mesenteric microcirculation. Rabbits fed a…”
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Mechanisms of thrombotic microangiopathy following xenogeneic hematopoietic progenitor cell transplantation by Alwayn, I P, Buhler, L, Appel, 3rd, J Z, Goepfert, C, Csizmadia, E, Correa, L, Harper, D, Kitamura, H, Down, J, Awwad, M, Sackstein, R, Cooper, D K, Robson, S C

“…Attempts to induce tolerance though mixed hematopoietic chimerism in the discordant pig-to-baboon xenotransplantation model are sometimes complicated by a…”
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Modulation of platelet aggregation in baboons : Implications for mixed chimerism in xenotransplantation. I. The roles of individual components of a transplantation conditioning regimen and of pig peripheral blood progenitor cells by APPEL, James Z, ALWAYN, Ian P. J, BUHLER, Leo, DEANGELIS, Holly A, ROBSON, Simon C, COOPER, David K. C

“…The induction of tolerance to pig antigens in primates may facilitate the development of successful clinical xenotransplantation protocols. The infusion of…”
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Adult porcine islet transplantation in baboons treated with conventional immunosuppression or a non-myeloablative regimen and CD154 blockade by Bühler, L., Deng, S., O'Neil, J., Kitamura, H., Koulmanda, M., Baldi, A., Rahier, J., Alwayn, I.P.J., Appel, J.Z., Awwad, M., Sachs, D.H., Weir, G., Squifflet, J.P., Cooper, D.K.C., Morel, Ph

“…The aim of the present study was to assess the survival of adult porcine islets transplanted into baboons receiving either (1) conventional triple drug…”
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Modulation of platelet aggregation in baboons : Implications for mixed chimerism in xenotransplantation. II. The effects of cyclophosphamide on pig peripheral blood progenitor cell-induced aggregation by APPEL, James Z, ALWAYN, Ian P. J, CORREA, Laura E, COOPER, David K. C, ROBSON, Simon C

“…The induction of tolerance to pig antigens in primates may facilitate the development of successful clinical xenotransplantation protocols. The infusion of…”
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Anti-CD154 monoclonal antibody and thromboembolism by BUHLER, Leo, ALWAYN, Ian P. J, APPEL, James Z, ROBSON, Simon C, COOPER, David K. C

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Pig kidney transplantation in baboons: Anti-GALα1-3GAL IGM alone is associated with acute humoral xenograft rejection and disseminated intravascular coagulation by BÜHLER, L, YAMADA, K, AWWAD, M, COOPER, D. K. C, KITAMURA, H, ALWAYN, I. P. J, BASKER, M, APPEL, J. Z, COLVIN, R. B, WHITE-SCHARF, M. E, SACHS, D. H, ROBSON, S. C

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Pharmacotherapeutic agents in xenotransplantation by Basker, M, Buhler, L, Alwayn, I P, Appel, 3rd, J Z, Cooper, D K

“…The ability to transplant pig organs into humans would resolve the current crisis in the supply of cadaveric human organs for the treatment of end stage…”
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Hepatitis B core antibody positive donors as a safe and effective therapeutic option to increase available organs for lung transplantation by HARTWIG, Matthew G, PATEL, Vijay, PALMER, Scott M, CANTU, Edward, APPEL, James Z, MESSIER, Robert H, DAVIS, R. Duane

“…The use of hepatitis B core antibody (HBcAb+) and hepatitis C antibody (HCV Ab+) positive donors represents one strategy to increase available donor organs,…”
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Role of flow cytometry to define unacceptable HLA antigens in lung transplant recipients with HLA-specific antibodies by APPEL, James Z, HARTWIG, Matthew G, CANTU, Edward, PALMER, Scott M, REINSMOEN, Nancy L, DAVIS, R. Duane

“…Antidonor HLA-specific antibodies have been associated with hyperacute rejection and primary graft failure in lung transplant recipients. Thus, transplant…”
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Cellular mechanisms of heparinase III protection in rat traumatic shock by Hayward, R, Scalia, R, Hopper, B, Appel, 3rd, J Z, Lefer, A M

“…Pentobarbital-anesthetized rats subjected to traumatic shock developed a shock state characterized by marked hypotension to 65-70 mmHg, a survival time of 88…”
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Pig kidney transplantation in baboons: Anti-Gal alpha 1-3Gal IgM alone is associated with acute humoral xenograft rejection and disseminated intravascular coagulation by Buhler, L, Yamada, K, Kitamura, H, Alwayn, IPJ, Basker, M, Appel, JZ III, Colvin, R B, White-Scharf, ME, Sachs, D H, Robson, S C, Awwad, M, Cooper, DKC

“…Kidneys harvested from miniature swine or pigs transgenic for human decay-accelerating factor (hDAF) were transplanted into baboons receiving an anti-CD154…”
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The Pig as a Source of Cardiac Xenografts by Appel, James Z., Buhler, Leo, Cooper, David K. C.

“…ABSTRACT The inadequate availability of human donor hearts and other organs has inspired interest in the field of xenotransplantation. Historically, ten…”
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Inhibition of platelet aggregation in baboons: therapeutic implications for xenotransplantation by Alwayn, Ian P. J., Appel III, James Z., Goepfert, Christian, Buhler, Leo, Cooper, David K. C., Robson, Simon C.

“…Methods: Drugs tested in these experiments were aurintricarboxylic acid (ATA, von Willebrand Factor‐GPIb inhibitor), fucoidin (a selectin‐inhibitor),…”
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Pig kidney transplantation in baboons: anti-Gal(alpha)1-3Gal IgM alone is associated with acute humoral xenograft rejection and disseminated intravascular coagulation by Bühler, L, Yamada, K, Kitamura, H, Alwayn, I P, Basker, M, Appel, 3rd, J Z, Colvin, R B, White-Scharf, M E, Sachs, D H, Robson, S C, Awwad, M, Cooper, D K

“…Kidneys harvested from miniature swine or pigs transgenic for human decay-accelerating factor (hDAF) were transplanted into baboons receiving an anti-CD154…”
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New drugs: the AMA and the FDA by Appel, J Z

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"The push-button era of medicine" by Appel, J Z

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Xenotransplantation: The Challenge to Current Psychosocial Attitudes by Appel, James Z., Alwayn, Ian P. J., Cooper, David K. C.

“…Because of the limited availability of transplantable human organs, xenotransplantation, the use of animal organs as an alternative source, has received…”
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Activation of human endothelial cells by mobilized porcine leukocytes in vitro: Implications for mixed chimerism in xenotransplantation by APPEL, James Z, NEWMAN, Dawn, AWWAD, Michel, GRAY, Huw S, DOWN, Julian, COOPER, David K. C, ROBSON, Simon C

“…The induction of immunologic tolerance to pig antigens in primates may facilitate the development of successful clinical xenotransplantation protocols. The…”
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