Search Results - "APFELBAUM, J"

Staff resilience and innovation essential to New York City diabetes prevention programs going virtual during COVID-19 pandemic lockdowns by Smith, Eleanor J, Apfelbaum, Leora J, Yeh, Ming-Chin, Horlyck-Romanovsky, Margrethe F

“…COVID-19 lockdowns in March 2020 forced National Diabetes Prevention Programs (DPPs) to pause, cancel or reformulate. This qualitative study sought to (a)…”
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Postoperative Pain Experience: Results from a National Survey Suggest Postoperative Pain Continues to Be Undermanaged by Apfelbaum, Jeffrey L., Chen, Connie, Mehta, Shilpa S., Gan, Tong J.

“…Postoperative pain can have a significant effect on patient recovery. An understanding of patient attitudes and concerns about postoperative pain is important…”
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Hemodynamic effects of propofol : data from over 25,000 patients by HUG, C. C, MCLESKEY, C. H, NAHRWOLD, M. L, ROIZEN, M. F, STANLEY, T. H, THISTED, R. A, WALAWANDER, C. A, WHITE, P. F, APFELBAUM, J. L, GRASELA, T. H

“…To investigate clinically important hypotension and bradycardia after induction of anesthesia with propofol, we analyzed data from a Phase IV stepwise study…”
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Using alcohol as a standard to assess the degree of impairment induced by sedative and analgesic drugs used in ambulatory surgery by PANKAJ THAPAR, ZACNY, J. P, THOMPSON, W, APFELBAUM, J. L

“…There is a need for a standard by which to compare the degree of subjective and behavioral impairment caused by anesthetic drugs, because anesthesiologists may…”
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Propofol at a Subanesthetic Dose May Have Abuse Potential in Healthy Volunteers by Zacny, James P., Lichtor, J. Lance, Thompson, Wesley, Apfelbaum, Jeffrey L.

“…We conducted a study in which the rewarding effects of propofol were assessed in humans, using a discrete-trials choice procedure. Normal healthy volunteers (n…”
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Opioid Abuse or Dependence Increases 30-day Readmission Rates after Major Operating Room Procedures: A National Readmissions Database Study by Gupta, Atul, Nizamuddin, Junaid, Elmofty, Dalia, Nizamuddin, Sarah L, Tung, Avery, Minhaj, Mohammed, Mueller, Ariel, Apfelbaum, Jeffrey, Shahul, Sajid

“…BACKGROUND:Although opioids remain the standard therapy for the treatment of postoperative pain, the prevalence of opioid misuse is rising. The extent to which…”
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Subjective, psychomotor, cognitive, and analgesic effects of subanesthetic concentrations of Sevoflurane and nitrous oxide by GALINKIN, J. L, JANISZEWSKI, D, YOUNG, C. J, KLAFTA, J. M, KLOCK, P. A, COALSON, D. W, APFELBAUM, J. L, ZACNY, J. P

“…Sevoflurane is a volatile general anesthetic that differs in chemical nature from the gaseous anesthetic nitrous oxide. In a controlled laboratory setting, the…”
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Effects of a cold-water stressor on psychomotor and cognitive functioning in humans by Patil, Priya G., Apfelbaum, Jeffrey L., Zacny, James P.

“…The effects of an acute stressful and painful stimulus, cold water, on psychomotor and cognitive functioning, was assessed in 14 healthy volunteers. Subjects…”
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Awakening, Clinical Recovery, and Psychomotor Effects After Desflurane and Propofol Anesthesia by Apfelbaum, Jeffrey L., Lichtor, J. Lance, Lane, Bradford S., Coalson, Dennis W., Korttila, Kari T.

“…We compared postanesthetic and residual recovery of desflurane versus propofol anesthesia.Twenty volunteers were anesthetized for 1 h at 1-wk intervals with…”
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Modulating effects of a cold water stimulus on opioid effects in volunteers by CONLEY, K. M, TOLEDANO, A. Y, APFELBAUM, J. L, ZACNY, J. P

“…The purpose of this study was to characterize the effect of a painful stimulus on morphine and butorphanol effects in healthy non-drug abusing volunteers…”
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Objective and Subjective Impairment from Often-Used Sedative/Analgesic Combinations in Ambulatory Surgery, Using Alcohol as a Benchmark by Thapar, Pankaj, Zacny, James P., Choi, Mark, Apfelbaum, Jeffrey L.

“…Impairment caused by different sedative/analgesic combinations commonly used in ambulatory settings was compared to that of alcohol at blood alcohol…”
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The initial clinical experience of 1819 physicians in maintaining anesthesia with propofol : characteristics associated with prolonged time to awakening by APFELBAUM, J. L, GRASELA, T. H, HUG, C. C, MCLESKEY, C. H, NAHRWOLD, M. L, ROIZEN, M. F, STANLEY, T. H, THISTED, R. A, WALAWANDER, C. A, WHITE, P. F

“…In October 1989, propofol underwent Phase IV Food and Drug Administration testing that involved 25,981 patients, 1722 institutions, and 1819 anesthesiologists…”
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Treatment of postoperative nausea and vomiting after outpatient surgery with the 5-HT3 antagonist ondansetron by SCUDERI, P, WETCHLER, B, WILLIAMS, M. F, YUNG-FONG SUNG, MINGUS, M, DUPEN, S, CLAYBON, L, LESLIE, J, TALKE, P, APFELBAUM, J, SAID SHARIFI-AZAD

“…Postoperative nausea and vomiting following outpatient surgery can significantly delay discharge. This study evaluates the safety and efficacy of ondansetron…”
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Unstable cervical spine without spinal cord injury in penetrating neck trauma by Apfelbaum, Jonathan D, Cantrill, Stephen V, Waldman, Neil

“…Cervical spine instability in the neurologically intact patient following penetrating neck trauma has been considered rare or non-existant. We present a case…”
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Subjective and psychomotor effects of subanesthetic doses of propofol in healthy volunteers by ZACNY, J. P, LICHTOR, J. L, COALSON, D. W, FINN, R. S, UITVLUGT, A. M, GLOSTEN, B, FLEMMING, D. C, APFELBAUM, J. L

“…Propofol is increasingly being used in medical and surgical procedures in which conscious sedation of the patient is desired. The mood-altering and psychomotor…”
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Randomized comparison of recovery after propofol-nitrous oxide versus thiopentone-isoflurane-nitrous oxide anaesthesia in patients undergoing ambulatory surgery by Korttila, K, Ostman, P, Faure, E, Apfelbaum, J L, Prunskis, J, Ekdawi, M, Roizen, M F

“…A randomized, prospective study was performed to compare recovery characteristics in 41 ASA physical status I-II patients scheduled for ambulatory surgery with…”
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Local anesthetic systemic toxicity by Dickerson, David M, Apfelbaum, Jeffrey L

“…Local anesthetic systemic toxicity (LAST) is a rare yet devastating complication from the administration of local anesthesia. The ability to recognize and…”
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Mivacurium chloride administration by infusion by Apfelbaum, J L

“…As a consequence of its rapid hydrolysis by plasma cholinesterase, mivacurium has a short duration of action, and recovery from neuromuscular blockade is rapid…”
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The effects of a cold-water immersion stressor on the reinforcing and subjective effects of fentanyl in healthy volunteers by Zacny, James P., McKay, Maura A., Toledano, Alicia Y., Marks, Sandy, Young, Christopher J., Klock, P.Allah, Apfelbaum, Jeffrey L.

“…The reinforcing and subjective effects of fentanyl, an opioid analgesic, were tested in ten healthy volunteers without histories of drug abuse, as a function…”
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Adverse events in a multicenter phase IV study of propofol : evaluation by anesthesiologists and postanesthesia care unit nurses by MCLESKEY, C. H, WALAWANDER, C. A, NAHRWOLD, M. L, ROIZEN, M. F, STANLEY, T. H, THISTED, R. A, WHITE, P. F, APFELBAUM, J. L, GRASELA, T. H, HUG, C. C

“…Phase II and III studies are tightly controlled trials investigating adverse effects before government approval of a new drug. However, because postapproval…”
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