IDENTIFICATION OF CHIKUNGUNYA VIRUS STRAINS CIRCULATING IN KELANTAN, MALAYSIA IN 2009

IDENTIFICATION OF CHIKUNGUNYA VIRUS STRAINS CIRCULATING IN KELANTAN, MALAYSIA IN 2009

Malaysia experienced its first outbreak of chikungunya virus (CHIKV) infection in late 1998 in Klang District in Selangor; six years later the virus re-emerged in the state of Perak. All the CHIKV isolates in 1988 and 2006 shared high sequence similarities and belonged to the Asian genotype. In 2007...

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Bibliographic Details
Published in:Southeast Asian journal of tropical medicine and public health Vol. 41; no. 6; pp. 1374 - 1380
Main Authors: APANDIL, Y, LAU, S. K, LZMAWATI, N, AMAL, N. M, FAUDZI, Y, MANSOR, Wan, HANI, M. H, ZAINAH, S
Format: Journal Article
Language:English
Published: Bangkok SEAMO, Regional Tropical Medicine and Public Health Network 01-11-2010
Central Coordinating Board, SEAMEO-TROPMED Project
Subjects:
Alphavirus Infections - epidemiology
Alphavirus Infections - virology
Biological and medical sciences
Chikungunya virus - classification
Chikungunya virus - isolation & purification
General aspects
Genotype
Humans
Malaysia - epidemiology
Medical sciences
Outbreaks
Phylogeny
Sequence Analysis
Vector-borne diseases
Asia
Malaysia
Virus
Togaviridae
Alphavirus
Tropical medicine
Identification
Chikungunya virus
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Summary:Malaysia experienced its first outbreak of chikungunya virus (CHIKV) infection in late 1998 in Klang District in Selangor; six years later the virus re-emerged in the state of Perak. All the CHIKV isolates in 1988 and 2006 shared high sequence similarities and belonged to the Asian genotype. In 2007 and 2008 CHIKV infection again reemerged but the genotype was the Central/East African genotype. This strain was found to be similar to the strains causing outbreaks in the India Ocean. In 2009, the strains circulating in Malaysia, including the state of Kelantan, based on the partial E1 gene, also belong to the Central/East African genotype.
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ISSN:0125-1562