Search Results - "AOYAMA, YUMI"

Immune reconstitution inflammatory syndrome in non‐HIV immunosuppressed patients by Sueki, Hirohiko, Mizukawa, Yoshiko, Aoyama, Yumi

“…Immune reconstitution inflammatory syndrome (IRIS) represents a clinical phenomenon of immune‐mediated inflammation against various antigens, including…”
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Japanese guidelines for the management and treatment of generalized pustular psoriasis: The new pathogenesis and treatment of GPP by Fujita, Hideki, Terui, Tadashi, Hayama, Koremasa, Akiyama, Masashi, Ikeda, Shigaku, Mabuchi, Tomotaka, Ozawa, Akira, Kanekura, Takuro, Kurosawa, Michiko, Komine, Mayumi, Nakajima, Kimiko, Sano, Shigetoshi, Nemoto, Osamu, Muto, Masahiko, Imai, Yasutomo, Yamanishi, Kiyofumi, Aoyama, Yumi, Iwatsuki, Keiji

“…Generalized pustular psoriasis (GPP) is a rare disease characterized by recurrent fever and systemic flushing accompanied by extensive sterile pustules. The…”
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Role of pro‐inflammatory cytokines in the pathophysiology of herpes simplex virus superinfection in Darier’s disease by Yamamoto, Takenobu, Aoyama, Yumi

“…Darier’s disease (DD) and Hailey–Hailey disease (HHD), belonging to a hereditary acantholytic dermatosis caused by mutations in ATP2A2 and ATP2C1,…”
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Risk of Progression to Autoimmune Disease in Severe Drug Eruption: Risk Factors and the Factor-Guided Stratification by Mizukawa, Yoshiko, Aoyama, Yumi, Takahashi, Hayato, Takahashi, Ryo, Shiohara, Tetsuo

“…The identification of risk factors is key not only to uncover the pathogenesis of autoimmune disease but also to predict progression to autoimmune disease…”
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Detection of multinucleated giant cells in differentiated keratinocytes with herpes simplex virus and varicella zoster virus infections by modified Tzanck smear method by Yamamoto, Takenobu, Aoyama, Yumi

“…Herpes simplex virus (HSV) and varicella zoster virus (VZV) infections induce the formation of intraepidermal vesicles containing acantholytic cells and…”
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SARS‐CoV‐2 vaccine‐triggered conversion from systemic lupus erythematosus (SLE) to bullous SLE and dipeptidyl peptidase 4 inhibitors‐associated bullous pemphigoid by Nakahara, Yukiko, Yamane, Mariko, Sunada, Midori, Aoyama, Yumi

“…Bullous systemic lupus erythematosus (BSLE) is a rare blistering disease in patients with SLE. BSLE is a heterogenous disease caused by autoantibodies to the…”
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Clinical features of dipeptidyl peptidase‐4 inhibitor‐associated bullous pemphigoid in Japan: A nationwide retrospective observational study by Sugiyama, Seiko, Yamamoto, Takenobu, Aoyama, Yumi

“…Many cases of bullous pemphigoid (BP) have been reported in patients taking dipeptidyl peptidase‐4 inhibitors (DPP‐4i), which are the most widely used…”
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Japanese guidelines for the management of pemphigoid (including epidermolysis bullosa acquisita) by Ujiie, Hideyuki, Iwata, Hiroaki, Yamagami, Jun, Nakama, Takekuni, Aoyama, Yumi, Ikeda, Shigaku, Ishii, Norito, Iwatsuki, Keiji, Kurosawa, Michiko, Sawamura, Daisuke, Tanikawa, Akiko, Tsuruta, Daisuke, Nishie, Wataru, Fujimoto, Wataru, Amagai, Masayuki, Shimizu, Hiroshi

“…The pemphigoid group is a category of autoimmune subepidermal blistering diseases in which autoantibodies deposit linearly at the epidermal basement membrane…”
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Herpes simplex virus-induced murine dry skin model through sweating disturbance by Asanuma, Yumiko, Ishimaru, Hironobu, Sato, Tetsuko, Yamamoto, Takenobu, Aoyama, Yumi

“…Given that ocular glands become infected secondarily to herpes simplex virus 1 (HSV-1) keratitis, resulting in the loss of tear production, sweat glands may…”
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Systemic capillary leak syndrome triggered by anti‐programmed death 1 checkpoint inhibitor in psoriasis by Umeda, Yoshiyasu, Hayashi, Hiroaki, Sugiyama, Seiko, Aoyama, Yumi

“…Programmed death 1 (PD‐1) inhibitors are increasingly used for the treatment of malignancies. Despite the clinical benefits, unpredictable and potentially…”
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Cell-to-cell transmission of HSV-1 in differentiated keratinocytes promotes multinucleated giant cell formation by Yamamoto, Yoshiko, Yamamoto, Takenobu, Aoyama, Yumi, Fujimoto, Wataru

“…•Differentiated keratinocytes can form multinucleated giant cell with HSV-1 infection.•HSV-1 infected differentiated keratinocytes can disrupt the adjacent…”
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Cathelicidin Antimicrobial Peptide LL-37 in Psoriasis Enables Keratinocyte Reactivity against TLR9 Ligands by Morizane, Shin, Yamasaki, Kenshi, Mühleisen, Beda, Kotol, Paul F., Murakami, Masamoto, Aoyama, Yumi, Iwatsuki, Keiji, Hata, Tissa, Gallo, Richard L.

“…Here we show that keratinocytes in psoriatic lesional skin express increased Toll-like receptor (TLR) 9 that similarly localizes with elevated expression of…”
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Anti-Cytomegalovirus Therapy: Whether and When to Initiate, Those Are the Questions by Aoyama, Yumi, Sugiyama, Seiko, Yamamoto, Takenobu

“…Cytomegalovirus (CMV) reactivation in patients with autoimmune bullous disease (AIBD) or severe drug eruption treated with immunosuppressive therapy was…”
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Sweat is a most efficient natural moisturizer providing protective immunity at points of allergen entry by Shiohara, Tetsuo, Mizukawa, Yoshiko, Shimoda-Komatsu, Yurie, Aoyama, Yumi

“…Although there is a growing acceptance that sweat could play a detrimental role in various allergic skin diseases, the possibility that sweat is also involved…”
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A multicenter, open-label, uncontrolled, single-arm phase 2 study of tirabrutinib, an oral Bruton’s tyrosine kinase inhibitor, in pemphigus by Yamagami, Jun, Ujiie, Hideyuki, Aoyama, Yumi, Ishii, Norito, Tateishi, Chiharu, Ishiko, Akira, Ichijima, Tomoki, Hagihara, Shunsuke, Hashimoto, Koji, Amagai, Masayuki

“…•Tirabrutinib, an oral BTK inhibitor, was evaluated in patients with pemphigus.•The complete remission rate with tirabrutinib after 24-week treatment was 18.8…”
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Biomarkers for predicting immune reconstitution inflammatory syndrome in dipeptidyl peptidase‐4 inhibitor‐associated bullous pemphigoid: A retrospective observational study with a case series by Sugiyama, Seiko, Yamamoto, Takenobu, Aoyama, Yumi

“…Background The prognosis of dipeptidyl peptidase‐4 inhibitor‐associated bullous pemphigoid (DPP‐4i‐BP) is variable, with some cases showing spontaneous…”
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Japanese guidelines for the management of pemphigus by Amagai, Masayuki, Tanikawa, Akiko, Shimizu, Tomoko, Hashimoto, Takashi, Ikeda, Shigaku, Kurosawa, Michiko, Niizeki, Hironori, Aoyama, Yumi, Iwatsuki, Keiji, Kitajima, Yasuo

“…The Committee for Guidelines for the Management of Pemphigus was organized as one element of the Japanese Dermatological Association (JDA) and the Ministry of…”
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Pityriasis Rubra Pilaris Type V as an Autoinflammatory Disease by CARD14 Mutations by Takeichi, Takuya, Sugiura, Kazumitsu, Nomura, Toshifumi, Sakamoto, Taiko, Ogawa, Yasushi, Oiso, Naoki, Futei, Yuko, Fujisaki, Aki, Koizumi, Akiko, Aoyama, Yumi, Nakajima, Kimiko, Hatano, Yutaka, Hayashi, Kei, Ishida-Yamamoto, Akemi, Fujiwara, Sakuhei, Sano, Shigetoshi, Iwatsuki, Keiji, Kawada, Akira, Suga, Yasushi, Shimizu, Hiroshi, McGrath, John A, Akiyama, Masashi

“…We found CARD14 mutations (2 de novo novel mutations and another previously reported mutation) in 3 of 3 patients with pityriasis rubra pilaris (PRP) type V,…”
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Aberrant EVI1 splicing contributes to EVI1-rearranged leukemia by Tanaka, Atsushi, Nakano, Taizo A., Nomura, Masaki, Yamazaki, Hiromi, Bewersdorf, Jan P., Mulet-Lazaro, Roger, Hogg, Simon, Liu, Bo, Penson, Alex, Yokoyama, Akihiko, Zang, Weijia, Havermans, Marije, Koizumi, Miho, Hayashi, Yasutaka, Cho, Hana, Kanai, Akinori, Lee, Stanley C., Xiao, Muran, Koike, Yui, Zhang, Yifan, Fukumoto, Miki, Aoyama, Yumi, Konuma, Tsuyoshi, Kunimoto, Hiroyoshi, Inaba, Toshiya, Nakajima, Hideaki, Honda, Hiroaki, Kawamoto, Hiroshi, Delwel, Ruud, Abdel-Wahab, Omar, Inoue, Daichi

“…Detailed genomic and epigenomic analyses of MECOM (the MDS1 and EVI1 complex locus) have revealed that inversion or translocation of chromosome 3 drives…”
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BRD9 determines the cell fate of hematopoietic stem cells by regulating chromatin state by Xiao, Muran, Kondo, Shinji, Nomura, Masaki, Kato, Shinichiro, Nishimura, Koutarou, Zang, Weijia, Zhang, Yifan, Akashi, Tomohiro, Viny, Aaron, Shigehiro, Tsukasa, Ikawa, Tomokatsu, Yamazaki, Hiromi, Fukumoto, Miki, Tanaka, Atsushi, Hayashi, Yasutaka, Koike, Yui, Aoyama, Yumi, Ito, Hiromi, Nishikawa, Hiroyoshi, Kitamura, Toshio, Kanai, Akinori, Yokoyama, Akihiko, Fujiwara, Tohru, Goyama, Susumu, Noguchi, Hideki, Lee, Stanley C., Toyoda, Atsushi, Hinohara, Kunihiko, Abdel-Wahab, Omar, Inoue, Daichi

“…ATP-dependent chromatin remodeling SWI/SNF complexes exist in three subcomplexes: canonical BAF (cBAF), polybromo BAF (PBAF), and a newly described…”
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