Search Results - "AOUACHERIA, Abdel"

KCTD: A new gene family involved in neurodevelopmental and neuropsychiatric disorders by Teng, Xinchen, Aouacheria, Abdel, Lionnard, Loïc, Metz, Kyle A., Soane, Lucian, Kamiya, Atsushi, Hardwick, J. Marie

“…The underlying molecular basis for neurodevelopmental or neuropsychiatric disorders is not known. In contrast, mechanistic understanding of other brain…”
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Evidence for existence of an apoptosis‐inducing BH3‐only protein, sayonara, in Drosophila by Ikegawa, Yuko, Combet, Christophe, Groussin, Mathieu, Navratil, Vincent, Safar‐Remali, Sabrina, Shiota, Takuya, Aouacheria, Abdel, Yoo, Sa Kan

“…Cells need to sense stresses to initiate the execution of the dormant cell death program. Since the discovery of the first BH3‐only protein Bad, BH3‐only…”
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Redefining the BH3 Death Domain as a ‘Short Linear Motif’ by Aouacheria, Abdel, Combet, Christophe, Tompa, Peter, Hardwick, J. Marie

“…B cell lymphoma-2 (BCL-2)-related proteins control programmed cell death through a complex network of protein–protein interactions mediated by BCL-2 homology 3…”
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Database and Bioinformatic Analysis of BCL-2 Family Proteins and BH3-Only Proteins by Aouacheria, Abdel, Navratil, Vincent, Combet, Christophe

“…BCL-2 proteins correspond to a structurally, functionally, and phylogenetically heterogeneous group of regulators that play crucial roles in the life and death…”
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Connecting mitochondrial dynamics and life-or-death events via Bcl-2 family proteins by Aouacheria, Abdel, Baghdiguian, Stephen, Lamb, Heather M., Huska, Jason D., Pineda, Fernando J., Hardwick, J. Marie

“…The morphology of a population of mitochondria is the result of several interacting dynamical phenomena, including fission, fusion, movement, elimination and…”
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Mitochondrial morphology is associated with respiratory chain uncoupling in autism spectrum disorder by Frye, Richard E., Lionnard, Loïc, Singh, Indrapal, Karim, Mohammad A., Chajra, Hanane, Frechet, Mathilde, Kissa, Karima, Racine, Victor, Ammanamanchi, Amrit, McCarty, Patrick John, Delhey, Leanna, Tippett, Marie, Rose, Shannon, Aouacheria, Abdel

“…Autism spectrum disorder (ASD) is a neurodevelopmental disorder that is associated with unique changes in mitochondrial metabolism, including elevated…”
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Quantitative imaging and semiotic phenotyping of mitochondrial network morphology in live human cells by Charrasse, Sophie, Racine, Victor, Saint-Omer, Charlotte, Poquillon, Titouan, Lionnard, Loïc, Ledru, Marine, Gonindard, Christophe, Delaunois, Sandrine, Kissa, Karima, Frye, Richard E, Pastore, Manuela, Reynes, Christelle, Frechet, Mathilde, Chajra, Hanane, Aouacheria, Abdel

“…The importance of mitochondria in tissue homeostasis, stress responses and human diseases, combined to their ability to transition between various structural…”
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Evolution of Bcl-2 homology motifs: homology versus homoplasy by Aouacheria, Abdel, Rech de Laval, Valentine, Combet, Christophe, Hardwick, J. Marie

“…Bcl-2 family proteins regulate apoptosis in animals. This protein family includes several homologous proteins and a collection of other proteins lacking…”
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Quantification and Characterization of UVB-Induced Mitochondrial Fragmentation in Normal Primary Human Keratinocytes by Jugé, Romain, Breugnot, Josselin, Da Silva, Célia, Bordes, Sylvie, Closs, Brigitte, Aouacheria, Abdel

“…UV irradiation is a major environmental factor causing skin dryness, aging and cancer. UVB in particular triggers cumulative DNA damage, oxidative stress and…”
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Whi2 is a conserved negative regulator of TORC1 in response to low amino acids by Chen, Xianghui, Wang, Guiqin, Zhang, Yu, Dayhoff-Brannigan, Margaret, Diny, Nicola L, Zhao, Mingjun, He, Ge, Sing, Cierra N, Metz, Kyle A, Stolp, Zachary D, Aouacheria, Abdel, Cheng, Wen-Chih, Hardwick, J Marie, Teng, Xinchen

“…Yeast WHI2 was originally identified in a genetic screen for regulators of cell cycle arrest and later suggested to function in general stress responses…”
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Bcl-wav and the mitochondrial calcium uniporter drive gastrula morphogenesis in zebrafish by Prudent, Julien, Popgeorgiev, Nikolay, Bonneau, Benjamin, Thibaut, Julien, Gadet, Rudy, Lopez, Jonathan, Gonzalo, Philippe, Rimokh, Ruth, Manon, Stephen, Houart, Corinne, Herbomel, Philippe, Aouacheria, Abdel, Gillet, Germain

“…Bcl-2 proteins are acknowledged as key regulators of programmed cell death. However, increasing data suggest additional roles, including regulation of the cell…”
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Comment on "Sterilizing immunity in the lung relies on targeting fungal apoptosis-like programmed cell death" by Aouacheria, Abdel, Cunningham, Kyle W, Hardwick, J Marie, Palková, Zdena, Powers, Ted, Severin, Fedor F, Váchová, Libuše

“…Shlezinger (Reports, 8 September 2017, p. 1037) report that the common fungus , a cause of aspergillosis, undergoes caspase-dependent apoptosis-like cell death…”
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Involvement of BCL2 family members in the regulation of human oocyte and early embryo survival and death: gene expression and beyond by Boumela, Imene, Assou, Said, Aouacheria, Abdel, Haouzi, Delphine, Dechaud, Hervé, De Vos, John, Handyside, Alan, Hamamah, Samir

“…In women, up to 99.9% of the oocyte stockpile formed during fetal life is decimated by apoptosis. Apoptotic features are also detected in human preimplantation…”
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Phylogenomics of life-or-death switches in multicellular animals: Bcl-2, BH3-Only, and BNip families of apoptotic regulators by Aouacheria, Abdel, Brunet, Frédéric, Gouy, Manolo

“…In this report, we conducted a comprehensive survey of Bcl-2 family members, a divergent group of proteins that regulate programmed cell death by an…”
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Quantitative assessment of mitochondrial morphology relevant for studies on cellular health and environmental toxicity by Charrasse, Sophie, Poquillon, Titouan, Saint-Omer, Charlotte, Pastore, Manuela, Bordignon, Benoit, Frye, Richard E., Reynes, Christelle, Racine, Victor, Aouacheria, Abdel

“…Mitochondria are essential organelles that play crucial roles in cellular energy metabolism, calcium signaling and apoptosis. Their importance in tissue…”
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Differential mechanisms of asparaginase resistance in B-type acute lymphoblastic leukemia and malignant natural killer cell lines by Chien, Wei-Wen, Le Beux, Céline, Rachinel, Nicolas, Julien, Michel, Lacroix, Claire-Emmanuelle, Allas, Soraya, Sahakian, Pierre, Cornut-Thibaut, Aurélie, Lionnard, Loïc, Kucharczak, Jérôme, Aouacheria, Abdel, Abribat, Thierry, Salles, Gilles

“…Bacterial L-asparaginase (ASNase), hydrolyzing L-asparagine (Asn), is an important drug for treating patients with acute lymphoblastic leukaemia (ALL) and…”
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µ-Calpain conversion of antiapoptotic Bfl-1 (BCL2A1) into a prodeath factor reveals two distinct alpha-helices inducing mitochondria-mediated apoptosis by Valero, Juan García, Cornut-Thibaut, Aurélie, Jugé, Romain, Debaud, Anne-Laure, Giménez, Diana, Gillet, Germain, Bonnefoy-Bérard, Nathalie, Salgado, Jesús, Salles, Gilles, Aouacheria, Abdel, Kucharczak, Jérôme

“…Anti-apoptotic Bfl-1 and pro-apoptotic Bax, two members of the Bcl-2 family sharing a similar structural fold, are classically viewed as antagonist regulators…”
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Should we be afraid of dental robots? by Aouacheria, Abdel

“…As it seems likely that France, at the forefront in the use of surgical robotic platforms, will authorize the deployment of dental robots in the short term,…”
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Active fragments from pro- and antiapoptotic BCL-2 proteins have distinct membrane behavior reflecting their functional divergence by Guillemin, Yannis, Lopez, Jonathan, Gimenez, Diana, Fuertes, Gustavo, Valero, Juan Garcia, Blum, Loïc, Gonzalo, Philippe, Salgado, Jesùs, Girard-Egrot, Agnès, Aouacheria, Abdel

“…The BCL-2 family of proteins includes pro- and antiapoptotic members acting by controlling the permeabilization of mitochondria. Although the association of…”
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Invertebrate Data Predict an Early Emergence of Vertebrate Fibrillar Collagen Clades and an Anti-incest Model by Aouacheria, Abdel, Cluzel, Caroline, Lethias, Claire, Gouy, Manolo, Garrone, Robert, Exposito, Jean-Yves

“…Fibrillar collagens are involved in the formation of striated fibrils and are present from the first multicellular animals, sponges, to humans. Recently, a new…”
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