Search Results - "ANUFRIEV, Victor Ph"

Dimeric (Poly)Hydroxynaphthazarins, Metabolites of Echinoderms and Lichens: The History of the Synthesis and Structure Elucidation by Pelageev, Dmitry N, Borisova, Ksenia L, Anufriev, Victor Ph

“…This review provides information on the synthesis and revision of the structures of natural dimeric (poly)hydroxynaphthazarins, metabolites of echinoderms and…”
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Activity of New Synthetic (2-Chloroethylthio)-1,4-naphthoquinones in Prostate Cancer Cells by Dyshlovoy, Sergey A., Pelageev, Dmitry N., Jakob, Lea S., Borisova, Ksenia L., Hauschild, Jessica, Busenbender, Tobias, Kaune, Moritz, Khmelevskaya, Ekaterina A., Graefen, Markus, Bokemeyer, Carsten, Anufriev, Victor Ph, von Amsberg, Gunhild

“…Development of resistance to currently available standard therapies in advanced prostate cancer (PCa) emphasizes the need for novel therapeutic options. Here,…”
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Inspired by Sea Urchins: Warburg Effect Mediated Selectivity of Novel Synthetic Non-Glycoside 1,4-Naphthoquinone-6S-Glucose Conjugates in Prostate Cancer by Dyshlovoy, Sergey A, Pelageev, Dmitry N, Hauschild, Jessica, Sabutskii, Yurii E, Khmelevskaya, Ekaterina A, Krisp, Christoph, Kaune, Moritz, Venz, Simone, Borisova, Ksenia L, Busenbender, Tobias, Denisenko, Vladimir A, Schlüter, Hartmut, Bokemeyer, Carsten, Graefen, Markus, Polonik, Sergey G, Anufriev, Victor Ph, Amsberg, Gunhild von

“…The phenomenon of high sugar consumption by tumor cells is known as Warburg effect. It results from a high glycolysis rate, used by tumors as preferred…”
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Successful Targeting of the Warburg Effect in Prostate Cancer by Glucose-Conjugated 1,4-Naphthoquinones by Dyshlovoy, Sergey A, Pelageev, Dmitry N, Hauschild, Jessica, Borisova, Ksenia L, Kaune, Moritz, Krisp, Christoph, Venz, Simone, Sabutskii, Yurii E, Khmelevskaya, Ekaterina A, Busenbender, Tobias, Denisenko, Vladimir A, Pokhilo, Natalia D, Atopkina, Lyubov N, Graefen, Markus, Schlüter, Hartmut, Stonik, Valentin A, Bokemeyer, Carsten, Anufriev, Victor Ph, von Amsberg, Gunhild

“…Treatment of castration-resistant prostate cancer (CRPC) remains challenging due to the development of drug resistance. The Warburg effect describes the…”
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Echinamines A and B, First Aminated Hydroxynaphthazarins from the Sea Urchin Scaphechinus mirabilis by MISCHENKO, Natalia P., FEDOREYEV, Sergey A., POKHILO, Nataly D., ANUFRIEV, Victor Ph, DENISENKO, Vladimir A., GLAZUNOV, Valery P.

“…Two new spinochromes, echinamines A (1) and B (2), were isolated from the sea urchin Scaphechinus mirabilis. Compounds 1 and 2 represent the first examples of…”
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A simple synthesis of natural spinazarins and their analogues by Pelageev, Dmitry N., Borisova, Ksenia L., Kovach, Svetlana M., Makhankov, Vyacheslav V., Anufriev, Victor Ph

“…[Display omitted] A short simple synthesis of spinazarins (2,3-dihydroxy-naphthazarins or 2,3,5,8-tetrahydroxy-1,4-naphtho-quinones) from available…”
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In vitro and in vivo investigations of novel 1,4-napthoquinone sulphomethylene carbohydrate conjugates in prostate cancer by Busenbender, Tobias, Dyshlovoy, Sergey, Kaune, Moritz, Boeckelmann, Lukas, Lange, Tobias, Schumacher, Udo, Pelageev, Dmitry N, Sabutskii, Yurii E, Borisova, Ksenia, Anufriev, Victor Ph, Graefen, Markus, Bokemeyer, Carsten, Von Amsberg, Gunhild

“…Abstract only 104 Background: The Warburg effect describes the ability of cancer cells to consume larger amounts of glucose in comparison to normal tissue, due…”
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Unexpected conversion of echinochrome to brominated spinochrome D. Synthesis of 2-amino-3,6,7-trihydroxynaphthazarin produced by the sea urchins Strongylocentrotus nudus and Psammechinus miliaris by Melman, Galina I., Borisova, Ksenia L., Pokhilo, Nataly D., Makhankov, Vyacheslav V., Anufriev, Victor Ph

“…[Display omitted] Two approaches to the total synthesis of 2-amino-3,6,7-trihydroxynaphthazarin, a metabolite of the sea urchins Strongylocentrotus nudus and…”
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Quinone–carbohydrate nonglucoside conjugates as a new type of cytotoxic agents: Synthesis and determination of in vitro activity by Pelageev, Dmitry N., Dyshlovoy, Sergey A., Pokhilo, Nataly D., Denisenko, Vladimir A., Borisova, Ksenia L., Keller-von Amsberg, Gunhild, Bokemeyer, Carsten, Fedorov, Sergey N., Honecker, Friedemann, Anufriev, Victor Ph

“…We have found that 2-methoxy-1,4-naphthoquinones easily react with primary alcohols to produce the corresponding 2-alkoxyderivatives. Using this reaction, we…”
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Revision of the structure of cuculoquinone to 3,3′-bis(6-ethyl-2,5,7,8-tetrahydroxy-1,4-naphthoquinone) and confirmation of the proposed structure by synthesis by Pokhilo, Nataly D., Dragan, Sergey V., Anufriev, Victor Ph

“…A reinvestigation of cuculoquinone, previously isolated from the lichen Cetraria cucullata, led to a revision of the proposed structure to…”
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Preparative production of spinochrome E, a pigment of different sea urchin species by Shestak, Olga P, Anufriev, Victor Ph, Novikov, Vyacheslav L

“…A concise route to spinochrome E (1) (2,3,5,6,7,8-hexahydroxy-1,4-naphthoquinone), a pigment isolated from sea urchins of different species, has been developed…”
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Synthesis, Cytotoxic and Contraceptive Activity of 6,8,9-Trihydroxy-2-methyl-2H-naphtho[2,3-b]pyran-5,10-dione, a Pigment of Echinothrix diadema, and its Analogs by Pokhilo, Natalia D, Melman, Galina I, Kiseleva, Marina I, Denisenko, Vladimir A, Anufriev, Victor Ph

“…6,8,9-Trihydroxy-2-methyl-2H-naphtho[2,3-b]pyran-5,10-dion, a pigment of the sea urchin Echinothrix diadema, and six analogs were synthesized. The cytotoxic…”
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Total synthesis of hybocarpone, a cytotoxic naphthazarin derivative from the lichen Lecanora hybocarpa, and related compounds by Dragana, Sergey V, Pushilin, Michael A, Glazunov, Valery P, Denisenko, Vladimir A, Anufriev, Victor Ph

“…The concise synthesis of the lichen-derived antitumor agent hybocarpone (1) and its analogs is described. A new synthetic approach is based on the direct…”
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Regiospecificity in the reaction of 2,3-dichloronaphthazarins with azide anions. Synthesis of echinamine A—a metabolite produced by the sea urchin Scaphechinus mirabilis by Pokhilo, Nataly D., Yakubovskaya, Alla Ya, Denisenko, Vladimir A., Anufriev, Victor Ph

“…It was found that 6-hydroxy- and 6-alkoxy-2,3-dichloronaphthazarins react smoothly with sodium azide in methanol to produce the corresponding 2-azido…”
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Concerning the structure of islandoquinone isolated from the lichen Cetraria islandica by Borisova, Ksenia L, Pelageev, Dmitry N, Kochergina, Tatiana Yu, Pokhilo, Nataly D, Pushilin, Michael A, Denisenko, Vladimir A, Berdyshev, Dmitry V, Anufriev, Victor Ph

“…An investigation of the oxidative coupling products of some substituted hydroxynaphthazarins led to a revision of the proposed structure of islandoquinone,…”
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Synthesis of ginsenoside Rg3, a minor constituent of Ginseng Radix by Anufriev, Victor Ph, Malinovskaya, Galina V., Denisenko, Vladimir A., Uvarova, Nina I., Elyakov, Georgi B., Kim, Shin-Il, Baek, Nam-In

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Synthesis of Echinamines A and B, the First Aminated Hydroxynaphthazarins Produced by the Sea Urchin Scaphechinus mirabilis and Its Analogues by POKHILO, Nataly D., SHUVALOVA, Maria I., LEBEDKO, Maxim V., SOPELNYAK, Galina I., YAKUBOVSKAYA, Alla Ya, MISCHENKO, Natalia P., FEDOREYEV, Sergey A., ANUFRIEV, Victor Ph

“…The first total synthesis of two marine aminated hydroxynaphthazarins, echinamines A (3-amino-7-ethyl-2,5,6,8-tetrahydroxy-1,4-naphthoquinone) and B…”
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First direct observation of tautomerism of monohydroxynaphthazarins by IR-spectroscopy by Glazunov, Valery P., Tchizhova, Alla Ya, Pokhilo, Nataly D., Anufriev, Victor Ph, Elyakov, George B.

“…Some substituted monohydroxylated naphthazarins (5,8-dihydroxy-1,4-naphthoquinones) were synthesized and studied by IR-spectroscopy in aprotic organic solvents…”
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Echinamines A and B, First Aminated Hydroxynaphthazarins from the Sea Urchin Scaphechinus m irabilis by Mischenko, Natalia P., Fedoreyev, Sergey A., Pokhilo, Nataly D., Anufriev, Victor Ph, Denisenko, Vladimir A., Glazunov, Valery P.

“…Two new spinochromes, echinamines A (1) and B (2), were isolated from the sea urchin Scaphechinus mirabilis. Compounds 1 and 2 represent the first examples of…”
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Synthesis of Echinamines A and B, the First Aminated Hydroxynaphthazarins Produced by the Sea Urchin Scaphechinus m irabilis and Its Analogues by Pokhilo, Nataly D, Shuvalova, Maria I, Lebedko, Maxim V, Sopelnyak, Galina I, Yakubovskaya, Alla Ya, Mischenko, Natalia P, Fedoreyev, Sergey A, Anufriev, Victor Ph

“…The first total synthesis of two marine aminated hydroxynaphthazarins, echinamines A (3-amino-7-ethyl-2,5,6,8-tetrahydroxy-1,4-naphthoquinone) and B…”
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