Search Results - "ANTONICELLI, Frank"
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Autoantibodies Associated With Connective Tissue Diseases: What Meaning for Clinicians?
Published in Frontiers in immunology (26-03-2018)“…Connective tissue diseases (CTDs) such as systemic lupus erythematosus, systemic sclerosis, myositis, Sjögren's syndrome, and rheumatoid arthritis are systemic…”
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2
Targeting the Tumor Microenvironment: The Protumor Effects of IL-17 Related to Cancer Type
Published in International journal of molecular sciences (01-09-2016)“…The inflammatory process contributes to immune tolerance as well as to tumor progression and metastasis. By releasing extracellular signals, cancerous cells…”
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The Interleukin-17 Family of Cytokines in Breast Cancer
Published in International journal of molecular sciences (01-12-2018)“…Breast cancer (BC) is the most common cancer in women worldwide and remains a major cause of mortality with an expected 137,000 death this year in Europe…”
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Neutrophil Extracellular Traps Generation Relates with Early Stage and Vascular Complications in Systemic Sclerosis
Published in Journal of clinical medicine (07-07-2020)“…Systemic sclerosis (SSc) is a systemic disease characterized by a great clinical and immunological heterogeneity whose pathophysiology is still being…”
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Eosinophil Cationic Protein (ECP), a predictive marker of bullous pemphigoid severity and outcome
Published in Scientific reports (06-07-2017)“…Bullous Pemphigoid (BP) is an inflammatory rare autoimmune bullous dermatosis, which outcome cannot be predicted through clinical investigations. Eosinophils…”
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Bullous pemphigoid outcome is associated with CXCL10-induced matrix metalloproteinase 9 secretion from monocytes and neutrophils but not lymphocytes
Published in Journal of allergy and clinical immunology (01-03-2017)“…Background The outcome of bullous pemphigoid (BP), the most frequent autoimmune skin-blistering disease, involves matrix metalloproteinase 9 (MMP-9), IL-17,…”
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IL-23/IL-17 Axis Activates IL-1β-Associated Inflammasome in Macrophages and Generates an Auto-Inflammatory Response in a Subgroup of Patients With Bullous Pemphigoid
Published in Frontiers in immunology (2019)“…Bullous Pemphigoid (BP) is a skin autoimmune blistering disease characterized by immune-mediated degradation of the dermo-epidermal junction and release of a…”
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NET Formation in Bullous Pemphigoid Patients With Relapse Is Modulated by IL-17 and IL-23 Interplay
Published in Frontiers in immunology (04-04-2019)“…DNA extracellular traps (ETs), released by neutrophils (NETs), or eosinophils (EETs), play a pathogenic role in several autoimmune disorders. However, to date,…”
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The elastin peptide VGVAPG increases CD4 + T-cell IL-4 production in patients with chronic obstructive pulmonary disease
Published in Respiratory research (13-01-2021)“…In chronic obstructive pulmonary disease (COPD), lung-infiltrating inflammatory cells secrete proteases and participate in elastin breakdown and genesis of…”
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10
IL-17A and its homologs IL-25/IL-17E recruit the c-RAF/S6 kinase pathway and the generation of pro-oncogenic LMW-E in breast cancer cells
Published in Scientific reports (08-07-2015)“…Pro-inflammatory IL-17 cytokines were initially described for their pathogenic role in chronic inflammatory diseases and subsequent accumulating evidence…”
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Characteristic Pattern of IL-17RA, IL-17RB, and IL-17RC in Monocytes/Macrophages and Mast Cells From Patients With Bullous Pemphigoid
Published in Frontiers in immunology (11-09-2019)“…Inflammation is largely implicated in bullous pemphigoid (BP), the most frequent skin auto-immune blistering disease. IL-17, essentially IL-17A/F, has been…”
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Prevalence and clinical significance of anti-laminin 332 autoantibodies detected by a novel enzyme-linked immunosorbent assay in mucous membrane pemphigoid
Published in JAMA dermatology (Chicago, Ill.) (01-05-2013)“…A rare variant of mucous membrane pemphigoid (MMP) is characterized by circulating anti-laminin 332 (Lam332) autoantibodies and seems to be associated with…”
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13
Blister Fluid Induces MMP-9-Associated M2-Type Macrophages in Bullous Pemphigoid
Published in Frontiers in immunology (07-08-2019)“…Bullous pemphigoid (BP) is a cutaneous autoimmune disease, characterized by an inflammatory cascade leading to blister formation. Although macrophages were…”
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Mucosal Involvement in Bullous Pemphigoid Is Mostly Associated with Disease Severity and to Absence of Anti-BP230 Autoantibody
Published in Frontiers in immunology (13-03-2018)“…Bullous pemphigoid (BP) is the most common autoimmune bullous disease and typically affects the elderly. Binding of specific autoantibodies to BP180/230…”
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15
Anti-Type VII Collagen Antibodies Are Identified in a Subpopulation of Bullous Pemphigoid Patients With Relapse
Published in Frontiers in immunology (21-03-2018)“…Bullous pemphigoid (BP) is an autoimmune bullous skin disease characterized by anti-BP180 and anti-BP230 autoantibodies (AAbs). Mucous membrane involvement is…”
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Bullous Pemphigoid: A Review of its Diagnosis, Associations and Treatment
Published in American journal of clinical dermatology (01-08-2017)“…Bullous pemphigoid (BP) is the most common autoimmune subepidermal blistering disease in Western countries, and typically affects the elderly. BP is…”
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Mechanical forces-induced human osteoblasts differentiation involves MMP-2/MMP-13/MT1-MMP proteolytic cascade
Published in Journal of cellular biochemistry (01-03-2012)“…Matrix metalloproteinase (MMP) family proteins play diverse roles in many aspects of cellular processes such as osteoblastic differentiation. Besides,…”
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Assessment of bullous pemphigoid disease area index during treatment: a prospective study of 30 patients
Published in Dermatology (Basel) (01-01-2014)“…Recently, a consensus Bullous Pemphigoid Disease Area Index (BPDAI) was proposed to measure therapeutic outcomes in bullous pemphigoid (BP). To compare BPDAI…”
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Role of the elastin receptor complex (S-Gal/Cath-A/Neu-1) in skin repair and regeneration
Published in Wound repair and regeneration (01-09-2009)“…ABSTRACT Impaired elastic fiber assembly constitutes one major problem in skin wound healing. Recent data indicate that a ternary complex involving a splicing…”
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The DNA hypomethylating agent, 5-aza-2′-deoxycytidine, enhances tumor cell invasion through a transcription-dependent modulation of MMP-1 expression in human fibrosarcoma cells
Published in Molecular carcinogenesis (01-01-2015)“…In diseases such as cancer, cells need to degrade the extracellular matrix (ECM) and therefore require high protease levels. Thus, aberrant tissue degradation…”
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