Sorafenib inhibits the imatinib-resistant KITT6701 gatekeeper mutation in gastrointestinal stromal tumor

Sorafenib inhibits the imatinib-resistant KITT6701 gatekeeper mutation in gastrointestinal stromal tumor

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Bibliographic Details
Published in:Clinical cancer research Vol. 13; no. 16; pp. 4874 - 4881
Main Authors: TIANHUA GUO, AGARAM, Narasimhan P, DEMATTEO, Ronald P, BESMER, Peter, ANTONESCUL, Cristina R, WONG, Grace C, HOM, Glory, D'ADAMO, David, MAKI, Robert G, SCHWARTZ, Gary K, VEACH, Darren, CLARKSON, Bayard D, SINGER, Samuel
Format: Journal Article
Language:English
Published: Philadelphia, PA American Association for Cancer Research 15-08-2007
Subjects:
Antineoplastic agents
Biological and medical sciences
Gastroenterology. Liver. Pancreas. Abdomen
Medical sciences
Pharmacology. Drug treatments
Stomach. Duodenum. Small intestine. Colon. Rectum. Anus
Tumors
Antineoplastic agent
Resistance
Imatinib
Enzyme
Transferases
Sorafenib
Enzyme inhibitor
Digestive diseases
Genetics
Mutation
Protein-tyrosine kinase
Gastrointestinal stromal tumor
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Description
ISSN:1078-0432
1557-3265
DOI:10.1158/1078-0432.CCR-07-0484