Search Results - "ANTONELLI, Lis R"
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The immunology of Plasmodium vivax malaria
Published in Immunological reviews (01-01-2020)“…Plasmodium vivax infection, the predominant cause of malaria in Asia and Latin America, affects ~14 million individuals annually, with considerable adverse…”
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Toxoplasma gondii-Induced Neutrophil Extracellular Traps Amplify the Innate and Adaptive Response
Published in mBio (26-10-2021)“…Toxoplasmosis affects one-third of the human population worldwide. Humans are accidental hosts and are infected after consumption of undercooked meat and water…”
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Elevated frequencies of highly activated CD4+ T cells in HIV+ patients developing immune reconstitution inflammatory syndrome
Published in Blood (11-11-2010)“…Immune reconstitution inflammatory syndrome (IRIS) is a considerable problem in the treatment of HIV-infected patients. To identify immunologic correlates of…”
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IFNs Reset the Differential Capacity of Human Monocyte Subsets to Produce IL-12 in Response to Microbial Stimulation
Published in The Journal of immunology (1950) (01-04-2021)“…Human primary monocytes are composed of a minor, more mature CD16 (CD14 ) population and a major CD16 (CD14 ) subset. The specific functions of CD16 versus…”
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Mycobacterial antigen driven activation of CD14++CD16- monocytes is a predictor of tuberculosis-associated immune reconstitution inflammatory syndrome
Published in PLoS pathogens (01-10-2014)“…Paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) is an aberrant inflammatory response occurring in a subset of TB-HIV…”
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Dynamics of T-Lymphocyte Activation Related to Paradoxical Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome in Persons With Advanced HIV
Published in Frontiers in immunology (07-10-2021)“…Most persons living with HIV (PLWH) experience a significant restoration of their immunity associated with successful inhibition of viral replication after…”
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Increased frequencies of circulating CCR5+ memory T cells are correlated to chronic chagasic cardiomyopathy progression
Published in Journal of leukocyte biology (01-09-2019)“…The infection with the protozoan parasite Trypanosoma cruzi causes Chagas disease, a neglected tropical disease in Latin America and an imported emerging…”
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Th1-driven immune reconstitution disease in Mycobacterium avium–infected mice
Published in Blood (04-11-2010)“…Following antiretroviral therapy, a significant proportion of HIV+ patients with mycobacterial coinfections develop a paradoxical, poorly understood…”
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CD4-CD8-αβ and γδ T cells display inflammatory and regulatory potentials during human tuberculosis
Published in PloS one (11-12-2012)“…T-cells play an important role controlling immunity against pathogens and therefore influence the outcome of human diseases. Although most T-lymphocytes…”
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IL-10 limits parasite burden and protects against fatal myocarditis in a mouse model of Trypanosoma cruzi infection
Published in The Journal of immunology (1950) (15-01-2012)“…Chagas' disease is a zoonosis prevalent in Latin America that is caused by the protozoan Trypanosoma cruzi. The immunopathogenesis of cardiomyopathy, the main…”
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Frequency of CXCR3 + CD8 + T-Lymphocyte Subsets in Peripheral Blood Is Associated With the Risk of Paradoxical Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome Development in Advanced HIV Disease
Published in Frontiers in immunology (01-04-2022)“…Tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) is a clinical aggravation of TB symptoms observed among a fraction of HIV…”
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Impaired Innate Immunity in Mice Deficient in Interleukin-1 Receptor-Associated Kinase 4 Leads to Defective Type 1 T Cell Responses, B Cell Expansion, and Enhanced Susceptibility to Infection with Toxoplasma gondii
Published in Infection and Immunity (01-12-2012)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Immunoregulatory mechanisms and CD4−CD8− (double negative) T cell subpopulations in human cutaneous leishmaniasis: A balancing act between protection and pathology
Published in International immunopharmacology (01-10-2008)“…Cellular immune responses directed against protozoan parasites are key for controlling pathogen replication and disease resolution. However, an uncontrolled,…”
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Journal Article Conference Proceeding -
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The CD14+CD16+ inflammatory monocyte subset displays increased mitochondrial activity and effector function during acute Plasmodium vivax malaria
Published in PLoS pathogens (01-09-2014)“…Infection with Plasmodium vivax results in strong activation of monocytes, which are important components of both the systemic inflammatory response and…”
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15
Cytotoxic CD8+ T cells recognize and kill Plasmodium vivax–infected reticulocytes
Published in Nature medicine (01-09-2018)“…Plasmodium vivax causes approximately 100 million clinical malaria cases yearly 1 , 2 . The basis of protective immunity is poorly understood and thought to be…”
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Disparate Immunoregulatory Potentials for Double-Negative (CD4⁻ CD8⁻) αβ and γδ T Cells from Human Patients with Cutaneous Leishmaniasis
Published in Infection and Immunity (01-11-2006)“…Although most T lymphocytes express the αβ T-cell receptor and either CD4 or CD8 molecules, a small population of cells lacking these coreceptors, CD4⁻ CD8⁻…”
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In Situ IL-12/23p40 Production during Mycobacterial Infection Is Sustained by CD11bhigh Dendritic Cells Localized in Tissue Sites Distinct from Those Harboring Bacilli
Published in The Journal of immunology (1950) (01-06-2009)“…Although IL-12/23p40 is known to play a major role in host resistance to Mycobacterium spp, the cellular source, tissue localization, and regulation of p40…”
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Intranasal Poly-IC treatment exacerbates tuberculosis in mice through the pulmonary recruitment of a pathogen-permissive monocyte/macrophage population
Published in The Journal of clinical investigation (01-05-2010)“…Type I IFN has been demonstrated to have major regulatory effects on the outcome of bacterial infections. To assess the effects of exogenously induced type I…”
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Selective expansion of polyfunctional pathogen-specific CD4+ T cells in HIV-1–infected patients with immune reconstitution inflammatory syndrome
Published in Blood (29-03-2012)“…Since the introduction of highly active antiretroviral therapies (ART), the prognosis for HIV-1 patients has improved immensely. However, approximately 25% of…”
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Promotion of neutralizing antibody-independent immunity to wild-type and SARS-CoV-2 variants of concern using an RBD-Nucleocapsid fusion protein
Published in Nature communications (17-08-2022)“…Both T cells and B cells have been shown to be generated after infection with SARS-CoV-2 yet protocols or experimental models to study one or the other are…”
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