Search Results - "ANTAL, Istvan"
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Mathematical modeling of transdermal delivery of topical drug formulations in a dynamic microfluidic diffusion chamber in health and disease
Published in PloS one (11-04-2024)“…Mathematical models of epidermal and dermal transport are essential for optimization and development of products for percutaneous delivery both for local and…”
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A Mass Spectrometry Strategy for Protein Quantification Based on the Differential Alkylation of Cysteines Using Iodoacetamide and Acrylamide
Published in International journal of molecular sciences (01-05-2024)“…Mass spectrometry has become the most prominent yet evolving technology in quantitative proteomics. Today, a number of label-free and label-based approaches…”
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3
Altered Glycosylation of Human Alpha-1-Acid Glycoprotein as a Biomarker for Malignant Melanoma
Published in Molecules (Basel, Switzerland) (03-10-2021)“…A high-resolution HILIC-MS/MS method was developed to analyze anthranilic acid derivatives of N-glycans released from human serum alpha-1-acid glycoprotein…”
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4
Drug excipients
Published in Current medicinal chemistry (01-09-2006)“…The therapeutical use of drugs involves the application of dosage forms, serving as carrier systems together with several excipients to deliver the active…”
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Transdermal Delivery of α-Aminophosphonates as Semisolid Formulations-An In Vitro-Ex Vivo Study
Published in Pharmaceutics (11-05-2023)“…α-Aminophosphonates are organophosphorus compounds with an obvious similarity with α-amino acids. Owing to their biological and pharmacological…”
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Fluid Dynamics Optimization of Microfluidic Diffusion Systems for Assessment of Transdermal Drug Delivery: An Experimental and Simulation Study
Published in Scientia pharmaceutica (01-06-2024)“…Organ-on-a-chip technologies show exponential growth driven by the need to reduce the number of experimental animals and develop physiologically relevant human…”
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The Effect of the Particle Size Reduction on the Biorelevant Solubility and Dissolution of Poorly Soluble Drugs with Different Acid-Base Character
Published in Pharmaceutics (13-01-2023)“…Particle size reduction is a commonly used process to improve the solubility and the dissolution of drug formulations. The solubility of a drug in the…”
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Structural and Functional Analysis of Excised Skins and Human Reconstructed Epidermis with Confocal Raman Spectroscopy and in Microfluidic Diffusion Chambers
Published in Pharmaceutics (01-08-2022)“…Several ex vivo and in vitro skin models are available in the toolbox of dermatological and cosmetic research. Some of them are widely used in drug penetration…”
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Study on Optimization of Wet Milling Process for the Development of Albendazole Containing Nanosuspension with Improved Dissolution
Published in Periodica polytechnica. Chemical engineering. (01-01-2020)“…The main objective of this work was to show the potential of the optimization of top-down wet planetary bead milling process parameters (milling speed, process…”
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Specific nasopharyngeal Corynebacterium strains serve as gatekeepers against SARS-CoV-2 infection
Published in GeroScience (01-10-2023)“…The SARS-CoV-2 virus is still causing a worldwide problem. The virus settles primarily on the nasal mucosa, and the infection and its course depend on…”
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Structural elucidation of hyaluronic acid gels after heat sterilisation
Published in Polymer testing (01-12-2013)“…The influence of heat sterilisation and hyaluronic acid (HA) concentration on the micro- and macrostructure of HA hydrogels was investigated. HA hydrogels of…”
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Microparticles, Microspheres, and Microcapsules for Advanced Drug Delivery
Published in Scientia pharmaceutica (01-09-2019)“…Microparticles, microspheres, and microcapsules are widely used constituents of multiparticulate drug delivery systems, offering both therapeutic and…”
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13
Use of antibiotic-impregnated bone grafts in a rabbit osteomyelitis model
Published in Technology and health care (23-10-2017)“…Both osteomyelitis and prosthetic joint infection can be treated surgically with the use of antibiotic loaded bone grafts, as part of local antimicrobial…”
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Quantitative determination of crystallinity of alpha-lactose monohydrate by Near Infrared Spectroscopy (NIRS)
Published in International journal of pharmaceutics (30-04-2003)“…The purpose of this study was to determine quantitatively the crystallinity in crystalline/amorphous powder mixtures of lactose, to asses the capability of…”
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Journal Article Conference Proceeding -
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Current Trends in the Analysis of Post-translational Modifications
Published in Chromatographia (2020)“…Post-translational modifications controlling a large number of biological functions are key aspects of protein diversity. They have an important role…”
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Real-time coating thickness measurement and defect recognition of film coated tablets with machine vision and deep learning
Published in International journal of pharmaceutics (25-07-2022)“…[Display omitted] This paper presents a system, where images acquired with a digital camera are coupled with image analysis and deep learning to identify and…”
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17
Determination of the Main Phase Transition Temperature of Phospholipids by Oscillatory Rheology
Published in Molecules (Basel, Switzerland) (29-06-2023)“…Knowledge of the physical and chemical properties of phospholipids, such as phase transition temperatures (Tc), is of great importance in order to reveal the…”
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Microparticles and multi-unit systems for advanced drug delivery
Published in European journal of pharmaceutical sciences (01-03-2024)“…Microparticles have unique benefits in the formulation of multiparticulate and multi-unit type pharmaceutical dosage forms allowing improved drug safety and…”
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Examining the Prevalence of Left Atrial Appendage Thrombus in a Cohort of Acute Stroke Patients with an Extended Computed Tomography Angiographic Protocol
Published in European neurology (2024)“…Current guidelines recommend transthoracic echocardiography (TTE) for routine screening of cardiac emboli; however, the visualization of the left atrial…”
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Rheological Considerations of Pharmaceutical Formulations: Focus on Viscoelasticity
Published in Gels (01-06-2023)“…Controlling rheological properties offers the opportunity to gain insight into the physical characteristics, structure, stability and drug release rate of…”
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