Search Results - "ANSELMI, Francesca"
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Intragenic DNA methylation prevents spurious transcription initiation
Published in Nature (London) (02-03-2017)“…In mammals, DNA methylation occurs mainly at CpG dinucleotides. Methylation of the promoter suppresses gene expression, but the functional role of gene-body…”
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2
Genome-wide profiling of mouse RNA secondary structures reveals key features of the mammalian transcriptome
Published in Genome biology (01-01-2014)“…The understanding of RNA structure is a key feature toward the comprehension of RNA functions and mechanisms of action. In particular, non-coding RNAs are…”
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3
Genome-scale deconvolution of RNA structure ensembles
Published in Nature methods (01-03-2021)“…RNA structure heterogeneity is a major challenge when querying RNA structures with chemical probing. We introduce DRACO, an algorithm for the deconvolution of…”
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4
High-throughput single-base resolution mapping of RNA 2΄-O-methylated residues
Published in Nucleic acids research (17-02-2017)“…Functional characterization of the transcriptome requires tools for the systematic investigation of RNA post-transcriptional modifications. 2΄-O-methylation…”
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5
Scanless two-photon excitation of channelrhodopsin-2
Published in Nature methods (01-10-2010)“…Generalized phase contrast and temporal focusing are combined to shape two-photon excitation patterns that elicit large photocurrents in ChR2-expressing…”
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6
Three-dimensional imaging and photostimulation by remote-focusing and holographic light patterning
Published in Proceedings of the National Academy of Sciences - PNAS (06-12-2011)“…Access to three-dimensional structures in the brain is fundamental to probe signal processing at multiple levels, from integration of synaptic inputs to…”
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7
Tissue memory relies on stem cell priming in distal undamaged areas
Published in Nature cell biology (01-05-2023)“…Epithelial cells that participated in wound repair elicit a more efficient response to future injuries, which is believed to be locally restricted. Here we…”
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8
An Interglomerular Circuit Gates Glomerular Output and Implements Gain Control in the Mouse Olfactory Bulb
Published in Neuron (Cambridge, Mass.) (01-07-2015)“…Odors elicit distributed activation of glomeruli in the olfactory bulb (OB). Crosstalk between co-active glomeruli has been proposed to perform a variety of…”
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DNMT3B supports meso-endoderm differentiation from mouse embryonic stem cells
Published in Nature communications (23-01-2023)“…The correct establishment of DNA methylation patterns during mouse early development is essential for cell fate specification. However, the molecular targets…”
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10
Factor VIII promotes angiogenesis and vessel stability regulating extracellular matrix proteins
Published in Haematologica (Roma) (01-10-2024)Get full text
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11
Single-Base Resolution Analysis of 5-Formyl and 5-Carboxyl Cytosine Reveals Promoter DNA Methylation Dynamics
Published in Cell reports (Cambridge) (10-02-2015)“…Ten eleven translocation (Tet) proteins oxidize 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine…”
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TET1 is controlled by pluripotency-associated factors in ESCs and downmodulated by PRC2 in differentiated cells and tissues
Published in Nucleic acids research (18-08-2015)“…Ten-eleven translocation (Tet) genes encode for a family of hydroxymethylase enzymes involved in regulating DNA methylation dynamics. Tet1 is highly expressed…”
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13
Genome-Wide Analysis of Smad7-Mediated Transcription in Mouse Embryonic Stem Cells
Published in International journal of molecular sciences (18-12-2021)“…Smad7 has been identified as a negative regulator of the transforming growth factor TGF-β pathway by direct interaction with the TGF-β type I receptor (TβR-I)…”
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14
HaTSPiL: A modular pipeline for high-throughput sequencing data analysis
Published in PloS one (15-10-2019)“…Next generation sequencing methods are widely adopted for a large amount of scientific purposes, from pure research to health-related studies. The decreasing…”
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15
Electrocardiographic Changes Induced by Endurance Training and Pubertal Development in Male Children
Published in The American journal of cardiology (01-03-2017)“…Abstract Training-induced electrocardiographic changes are common in adult athletes. However, a few data are available on electrocardiogram (ECG) in…”
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16
Gut microbiota depletion delays somatic peripheral nerve development and impairs neuromuscular junction maturation
Published in Gut microbes (01-01-2024)“…Gut microbiota is responsible for essential functions in human health. Several communication axes between gut microbiota and other organs via neural,…”
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Involvement of N4BP2L1 , PLEKHA4 , and BEGAIN genes in breast cancer and muscle cell development
Published in Frontiers in cell and developmental biology (24-05-2024)“…Patients with breast cancer show altered expression of genes within the pectoralis major skeletal muscle cells of the breast. Through analyses of The Cancer…”
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Growth Factor Stimulation Induces Cell Survival by c-Jun·ATF2-dependent Activation of Bcl-XL
Published in The Journal of biological chemistry (23-07-2010)“…Growth factor stimulation induces c-Jun-dependent survival of primary endothelial cells. However, the mechanism of c-Jun anti-apoptotic activity has not been…”
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Acute coronary syndromes during COVID-19
Published in European heart journal (07-06-2020)Get full text
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Atrial Enlargement in the Athlete's Heart: Assessment of Atrial Function May Help Distinguish Adaptive from Pathologic Remodeling
Published in Journal of the American Society of Echocardiography (01-02-2018)“…Intensive training is associated with hemodynamic changes that typically induce an enlargement of cardiac chambers, involving not only the ventricles but also…”
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