Search Results - "ANNAND, Robert R."

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    Generation of Human iPSCs by Reprogramming with the Unmodified Synthetic mRNA by Annand, Robert R

    “…Human-induced pluripotent stem cells (iPSCs) are showing great promise for both disease modeling and regenerative medicine. The choice of reprogramming methods…”
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    Journal Article
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    Active Site of Bee Venom Phospholipase A2:  The Role of Histidine-34, Aspartate-64 and Tyrosine-87 by Annand, Robert R, Kontoyianni, Maria, Penzotti, Julie E, Dudler, Thomas, Lybrand, Terry P, Gelb, Michael H

    Published in Biochemistry (Easton) (09-04-1996)
    “…In bee venom phospholipase A2, histidine-34 probably functions as a Brønsted base to deprotonate the attacking water. Aspartate-64 and tyrosine-87 form a…”
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  3. 3

    Regulation of Protein Phosphatase 2A Activity by Caspase-3 during Apoptosis by Santoro, Maxine F., Annand, Robert R., Robertson, Molly M., Peng, Yun-Wen, Brady, Matthew J., Mankovich, John A., Hackett, Maria C., Ghayur, Tariq, Walter, Gernot, Wong, Winnie W., Giegel, David A.

    Published in The Journal of biological chemistry (22-05-1998)
    “…Although the available evidence suggests that whereas the caspase family plays a major role in apoptosis, they are not the sole stimulators of death. A random…”
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    Caspase-1 (interleukin-1beta-converting enzyme) is inhibited by the human serpin analogue proteinase inhibitor 9 by Annand, R R, Dahlen, J R, Sprecher, C A, De Dreu, P, Foster, D C, Mankovich, J A, Talanian, R V, Kisiel, W, Giegel, D A

    Published in Biochemical journal (15-09-1999)
    “…The regulation of caspases, cysteine proteinases that cleave their substrates after aspartic residues, is poorly understood, even though they are involved in…”
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    A link between catalytic activity, IgE-independent mast cell activation, and allergenicity of bee venom phospholipase A2 by Dudler, T, Machado, DC, Kolbe, L, Annand, RR, Rhodes, N, Gelb, MH, Koelsch, K, Suter, M, Helm, BA

    Published in The Journal of immunology (1950) (01-09-1995)
    “…The molecular and cellular mechanisms controlling Ab isotype selection following encounter of a given Ag are still unclear, although the regulatory role of…”
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  9. 9

    Caspase-1 (interleukin-1β-converting enzyme) is inhibited by the human serpin analogue proteinase inhibitor 9 by ANNAND, Robert R., DAHLEN, Jeffrey R., SPRECHER, Cindy A., DREU, Piet DE, FOSTER, Donald C., MANKOVICH, John A., TALANIAN, Robert V., KISIEL, Walter, GIEGEL, David A.

    Published in Biochemical journal (15-09-1999)
    “…The regulation of caspases, cysteine proteinases that cleave their substrates after aspartic residues, is poorly understood, even though they are involved in…”
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    High-level expression in Escherichia coli and rapid purification of enzymatically active honey bee venom phospholipase A2 by Dudler, T, Chen, W Q, Wang, S, Schneider, T, Annand, R R, Dempcy, R O, Crameri, R, Gmachl, M, Suter, M, Gelb, M H

    Published in Biochimica et biophysica acta (02-12-1992)
    “…Bee venom phospholipase A2 (BV-PLA2) is a hydrolytic enzyme that specifically cleaves the sn-2 acyl bond of phospholipids at the lipid/water interface. The…”
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  13. 13

    Comparison of the antibody response to bee venom phospholipase A2 induced by natural exposure in humans or by immunization in mice by Schneider, Theres, Dudler, Thomas, Annand, Robert R., Gelb, Michael H., King, Te P., Suter, Mark

    Published in Journal of molecular recognition (01-03-1997)
    “…Two human and twelve murine monoclonal antibodies directed against the main bee venom allergen phospholipase A2 (PLA) were evaluated for their fine specificity…”
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