Search Results - "ANKER, S. D"

Consensus definition of sarcopenia, cachexia and pre-cachexia: Joint document elaborated by Special Interest Groups (SIG) “cachexia-anorexia in chronic wasting diseases” and “nutrition in geriatrics” by Muscaritoli, M, Anker, S.D, Argilés, J, Aversa, Z, Bauer, J.M, Biolo, G, Boirie, Y, Bosaeus, I, Cederholm, T, Costelli, P, Fearon, K.C, Laviano, A, Maggio, M, Fanelli, F. Rossi, Schneider, S.M, Schols, A, Sieber, C.C

“…Summary Chronic diseases as well as aging are frequently associated with deterioration of nutritional status, loss muscle mass and function (i.e. sarcopenia),…”
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Inflammatory mediators in chronic heart failure: an overview by Anker, Stefan D, von Haehling, Stephan

“…[...]the pathophysiology of CHF is exceedingly complex. [...]some substances from this group have been shown to improve endothelial function by inducing cNOS…”
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The Obesity Paradox in Heart Failure: Accepting Reality and Making Rational Decisions by Anker, SD, Haehling, S

“…The obesity paradox in chronic heart failure (HF) has a number of facets that require discussion. These involve beliefs, various statistical results, and…”
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The endotoxin-lipoprotein hypothesis by Rauchhaus, Mathias, Coats, Andrew JS, Anker, Stefan D

“…The advent of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins) has revolutionised the treatment of hypercholesterolaemia. Statin treatment,…”
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Novel endotypes in heart failure: effects on guideline-directed medical therapy by Tromp, J, Ouwerkerk, W, Demissei, B G, Anker, S D, Cleland, J G, Dickstein, K, Filippatos, G, van der Harst, P, Hillege, H L, Lang, C C, Metra, M, Ng, L L, Ponikowski, P, Samani, N J, van Veldhuisen, D J, Zannad, F, Zwinderman, A H, Voors, A A, van der Meer, P

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Request for regulatory guidance for cancer cachexia intervention trials by Fearon, KCH, Argiles, JM, Baracos, VE, Bernabei, R, Coats, AJS, Crawford, J, Deutz, NE, Doehner, W, Evans, WJ, Ferrucci, L, Garcia, JM, Gralla, RJ, Jatoi, A, Kalantar‐Zadeh, K, Lainscak, M, Morley, JE, Muscaritoli, M, Polkey, MI, Rosano, G, Rossi‐Fanelli, F, Schols, AM, Strasser, F, Vellas, B, Haehling, S, Anker, SD

“…In the last 10 years, some regulatory authorities have consistently suggested that the design of randomized controlled trials testing treatments for cachexia…”
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Wasting as an independent predictor of mortality in patients with cystic fibrosis by Sharma, R, Florea, V G, Bolger, A P, Doehner, W, Florea, N D, Coats, A J S, Hodson, M E, Anker, S D, Henein, M Y

“…BACKGROUND Cystic fibrosis (CF) is the most common life threatening autosomal recessive disorder in the white population. Wasting has long been recognised as a…”
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Anaemia is an independent predictor of poor outcome in patients with chronic heart failure by Szachniewicz, J, Petruk-Kowalczyk, J, Majda, J, Kaczmarek, A, Reczuch, K, Kalra, P.R, Piepoli, M.F, Anker, S.D, Banasiak, W, Ponikowski, P

“…Background: Mild anaemia frequently occurs in patients with chronic heart failure (CHF), particularly in the advanced stages of the disease. The correction of…”
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Cytokines and neurohormones relating to body composition alterations in the wasting syndrome of chronic heart failure by Anker, S.D., Ponikowski, P.P., Clark, A.L., Leyva, F., Rauchhaus, M., Kemp, M., Teixeira, M.M., Hellewell, P.G., Hooper, J., Poole-Wilson, P.A., Coats, A.J.S.

“…Background Chronic heart failure is one of a number of disorders associated with the development of a wasting syndrome. The precise mechanisms of this remain…”
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Elevated Levels of Asymmetric Dimethylarginine in Chronic Heart Failure: A Pathophysiologic Link Between Oxygen Radical Load and Impaired Vasodilator Capacity and the Therapeutic Effect of Allopurinol by Haehling, S, Bode‐Böger, S M, Martens‐Lobenhoffer, J, Rauchhaus, M, Schefold, J C, Genth‐Zotz, S, Karhausen, T, Cicoira, M, Anker, S D, Doehner, W

“…Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide–dependent vasodilation. In 113 patients with chronic heart failure (CHF) and 26…”
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Determinants and clinical outcome of uptitration of ACE-inhibitors and beta-blockers in patients with heart failure: a prospective European study by Ouwerkerk, W, Voors, A A, Anker, S D, Cleland, J G, Dickstein, K, Filippatos, G, van der Harst, P, Hillege, H L, Lang, C C, Ter Maaten, J M, Ng, L L, Ponikowski, P, Samani, N J, van Veldhuisen, D J, Zannad, F, Metra, M, Zwinderman, A H

“…Despite clear guidelines recommendations, most patients with heart failure and reduced ejection-fraction (HFrEF) do not attain guideline-recommended target…”
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Cachexia and aging: An update based on the fourth international cachexia meeting by Morley, J. E., Anker, S. D., Evans, W. J.

“…This manuscript highlights the new developments in the pathophysiology of anorexia, cachexia and sarcopenia, based on presentations given at the Fourth…”
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Cardiopulmonary exercise testing for prognosis in chronic heart failure : continuous and independent prognostic value from VE/VCO2 slope and peak VO2 by FRANCIS, D. P, SHAMIM, W, DAVIES, L. C, PIEPOLI, M. F, PONIKOWSKI, P, ANKER, S. D, COATS, A. J. S

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Xanthine oxidase inhibition for chronic heart failure: is allopurinol the next therapeutic advance in heart failure? by Doehner, W, Anker, S D

“…A substantial body of evidence has accumulated to suggest a role for the xanthine oxidase metabolic pathway in the pathophysiology of chronic heart failure and…”
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Cardiac cachexia: a syndrome with impaired survival and immune and neuroendocrine activation by Anker, S D, Coats, A J

“…Chronic heart failure (CHF) is a complex syndrome affecting many body systems. Body wasting (ie, cardiac cachexia) is a serious complication of CHF long known…”
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Impaired Insulin Sensitivity as an Underlying Mechanism Linking Hepatitis C and Posttransplant Diabetes Mellitus in Kidney Recipients by Baid‐Agrawal, S., Frei, U., Reinke, P., Schindler, R., Kopp, M. A., Martus, P., Berg, T., Juergensen, J. S., Anker, S. D., Doehner, W.

“…Aim of this study was to investigate the mechanism/s associating hepatitis C virus (HCV) infection and posttransplant diabetes mellitus in kidney recipients…”
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Endotoxin and immune activation in chronic heart failure: a prospective cohort study by Niebauer, Josef, Volk, Hans-Dieter, Kemp, Michael, Dominguez, Martin, Schumann, Ralf R, Rauchhaus, Mathias, Poole-Wilson, Philip A, Coats, Andrew JS, Anker, Stefan D

“…Immune activation in patients with chronic heart failure may be secondary to endotoxin (lipopolysaccharide) action. We investigated the hypothesis that altered…”
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Iron deficiency and heart failure: diagnostic dilemmas and therapeutic perspectives by Jankowska, Ewa A, von Haehling, Stephan, Anker, Stefan D, Macdougall, Iain C, Ponikowski, Piotr

“…Iron is a micronutrient essential for cellular energy and metabolism, necessary for maintaining body homoeostasis. Iron deficiency is an important co-morbidity…”
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Hormonal changes and catabolic/anabolic imbalance in chronic heart failure and their importance for cardiac cachexia by ANKER, S. D, TUAN PENG CHUA, PONIKOWSKI, P, HARRINGTON, D, SWAN, J. W, KOX, W. J, POOLE-WILSON, P. A, COATS, A. J. S

“…The role of hormonal and cytokine abnormalities in the development of cardiac cachexia remains obscure. Healthy control subjects (n=16) and patients with…”
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Intraventricular conduction delay: a prognostic marker in chronic heart failure by Shamim, Waqar, Francis, Darrel P., Yousufuddin, Mohammed, Varney, Susan, Pieopli, Masimo F., Anker, Stefan D., Coats, Andrew J.S.

“…Chronic heart failure (CHF) is associated with high mortality, and there are several established clinical and laboratory parameters that predict mortality in…”
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