Search Results - "ANGLESIO, Michael S"

Endometriosis-associated Ovarian Cancers by Anglesio, Michael S, Yong, Paul J

“…Endometriosis-associated cancers include clear cell and endometrioid ovarian carcinoma. A history of endometriosis has long been considered to be a risk factor…”
Get full text

Oncogenic mutations in histologically normal endometrium: the new normal? by Lac, Vivian, Nazeran, Tayyebeh M, Tessier‐Cloutier, Basile, Aguirre‐Hernandez, Rosalia, Albert, Arianne, Lum, Amy, Khattra, Jaswinder, Praetorius, Teresa, Mason, Madeline, Chiu, Derek, Köbel, Martin, Yong, Paul J, Gilks, Blake C, Anglesio, Michael S, Huntsman, David G

“…The advent of next generation sequencing has vastly improved the resolution of mutation detection, thereby both increasing the resolution of the analysis of…”
Get full text

Clear cell carcinoma of the ovary: A report from the first Ovarian Clear Cell Symposium, June 24th, 2010 by Anglesio, Michael S, Carey, Mark S, Köbel, Martin, MacKay, Helen, Huntsman, David G

“…Abstract Objectives Recent literature has highlighted histological types of ovarian carcinoma as distinct diseases, each with unique clinical and molecular…”
Get full text

Type-specific cell line models for type-specific ovarian cancer research by Anglesio, Michael S, Wiegand, Kimberly C, Melnyk, Nataliya, Chow, Christine, Salamanca, Clara, Prentice, Leah M, Senz, Janine, Yang, Winnie, Spillman, Monique A, Cochrane, Dawn R, Shumansky, Karey, Shah, Sohrab P, Kalloger, Steve E, Huntsman, David G

“…OVARIAN CARCINOMAS CONSIST OF AT LEAST FIVE DISTINCT DISEASES: high-grade serous, low-grade serous, clear cell, endometrioid, and mucinous. Biomarker and…”
Get full text

Synchronous Endometrial and Ovarian Carcinomas: Evidence of Clonality by Anglesio, Michael S, Wang, Yi Kan, Maassen, Madlen, Horlings, Hugo M, Bashashati, Ali, Senz, Janine, Mackenzie, Robertson, Grewal, Diljot S, Li-Chang, Hector, Karnezis, Anthony N, Sheffield, Brandon S, McConechy, Melissa K, Kommoss, Friedrich, Taran, Florin A, Staebler, Annette, Shah, Sohrab P, Wallwiener, Diethelm, Brucker, Sara, Gilks, C Blake, Kommoss, Stefan, Huntsman, David G

“…Many women with ovarian endometrioid carcinoma present with concurrent endometrial carcinoma. Organ-confined and low-grade synchronous endometrial and ovarian…”
Get full text

Autophagy Inhibition Enhances Sunitinib Efficacy in Clear Cell Ovarian Carcinoma by DeVorkin, Lindsay, Hattersley, Matthew, Kim, Paul, Ries, Jenna, Spowart, Jaeline, Anglesio, Michael S, Levi, Samuel M, Huntsman, David G, Amaravadi, Ravi K, Winkler, Jeffrey D, Tinker, Anna V, Lum, Julian J

“…Clear cell ovarian carcinoma (CCOC) is an aggressive form of epithelial ovarian cancer that exhibits low response rates to systemic therapy and poor patient…”
Get full text

Targeted deep sequencing of mucinous ovarian tumors reveals multiple overlapping RAS-pathway activating mutations in borderline and cancerous neoplasms by Mackenzie, Robertson, Kommoss, Stefan, Winterhoff, Boris J, Kipp, Benjamin R, Garcia, Joaquin J, Voss, Jesse, Halling, Kevin, Karnezis, Anthony, Senz, Janine, Yang, Winnie, Prigge, Elena-Sophie, Reuschenbach, Miriam, Doeberitz, Magnus Von Knebel, Gilks, Blake C, Huntsman, David G, Bakkum-Gamez, Jamie, McAlpine, Jessica N, Anglesio, Michael S

“…Mucinous ovarian tumors represent a distinct histotype of epithelial ovarian cancer. The rarest (2-4 % of ovarian carcinomas) of the five major histotypes,…”
Get full text

IL6-STAT3-HIF Signaling and Therapeutic Response to the Angiogenesis Inhibitor Sunitinib in Ovarian Clear Cell Cancer by ANGLESIO, Michael S, GEORGE, Joshy, CHAKRAVARTY, Probir, GORRINGE, Kylie L, CAMPBELL, Ian G, OKAMOTO, Aikou, BIRRER, Michael J, HUNTSMAN, David G, DE FAZIO, Anna, KALLOGER, Steve E, BALKWILL, Frances, BLAKE GILKS, C, KULBE, Hagen, BOWTELL, David D, FRIEDLANDER, Michael, RISCHIN, Danny, LEMECH, Charlotte, POWER, Jeremy, COWARD, Jermaine, COWIN, Prue A, HOUSE, Colin M

“…Ovarian clear cell adenocarcinoma (OCCA) is an uncommon histotype that is generally refractory to platinum-based chemotherapy. We analyze here the most…”
Get full text

HACE1 is a potential tumor suppressor in osteosarcoma by El-Naggar, Amal M, Clarkson, Paul W., Negri, Gian Luca, Turgu, Busra, Zhang, Fan, Anglesio, Michael S., Sorensen, Poul H.

“…Osteosarcoma is a malignant bone sarcoma characterized by extensive genomic disruption and a propensity for metastatic spread. Osteoid production suggests a…”
Get full text

The Oncogenic Roles of DICER1 RNase IIIb Domain Mutations in Ovarian Sertoli-Leydig Cell Tumors by Wang, Yemin, Chen, Jiamin, Yang, Winnie, Mo, Fan, Senz, Janine, Yap, Damian, Anglesio, Michael S, Gilks, Blake, Morin, Gregg B, Huntsman, David G

“…Abstract DICER1, an endoribonuclease required for microRNA (miRNA) biogenesis, is essential for embryogenesis and the development of many organs including…”
Get full text

Morphologic and Molecular Characteristics of Mixed Epithelial Ovarian Cancers by Mackenzie, Robertson, Talhouk, Aline, Eshragh, Sima, Lau, Sherman, Cheung, Daphne, Chow, Christine, Le, Nhu, Cook, Linda S, Wilkinson, Nafisa, McDermott, Jacqueline, Singh, Naveena, Kommoss, Friedrich, Pfisterer, Jacobus, Huntsman, David G, Köbel, Martin, Kommoss, Stefan, Gilks, C Blake, Anglesio, Michael S

“…Epithelial ovarian cancer (EOC) consists of 5 major histotypeshigh-grade serous carcinoma (HGSC), endometrioid carcinoma (EC), clear cell carcinoma (CCC),…”
Get full text

FOXL2 molecular testing in ovarian neoplasms: diagnostic approach and procedural guidelines by Kommoss, Stefan, Anglesio, Michael S, Mackenzie, Robertson, Yang, Winnie, Senz, Janine, Ho, Julie, Bell, Lynda, Lee, Sylvia, Lorette, Julie, Huntsman, David G, Blake Gilks, C

“…A single, recurrent somatic point mutation (402C→G) in FOXL2 has been described in almost all adult-type granulosa cell tumors but not other ovarian neoplasms…”
Get full text

Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers by Helland, Åslaug, Anglesio, Michael S, George, Joshy, Cowin, Prue A, Johnstone, Cameron N, House, Colin M, Sheppard, Karen E, Etemadmoghadam, Dariush, Melnyk, Nataliya, Rustgi, Anil K, Phillips, Wayne A, Johnsen, Hilde, Holm, Ruth, Kristensen, Gunnar B, Birrer, Michael J, Pearson, Richard B, Børresen-Dale, Anne-Lise, Huntsman, David G, deFazio, Anna, Creighton, Chad J, Smyth, Gordon K, Bowtell, David D L

“…Molecular subtypes of serous ovarian cancer have been recently described. Using data from independent datasets including over 900 primary tumour samples, we…”
Get full text

Clinical and genetic analysis of recurrent adult-type granulosa cell tumor of the ovary: Persistent preservation of heterozygous c.402C>G FOXL2 mutation by Yanagida, Satoshi, Anglesio, Michael S, Nazeran, Tayyebeh M, Lum, Amy, Inoue, Momoko, Iida, Yasushi, Takano, Hirokuni, Nikaido, Takashi, Okamoto, Aikou, Huntsman, David G

“…Adult-type granulosa cell tumors of the ovary (aGCTs) are rare tumors that represent 2-5% of ovarian malignancies. The prognosis of this tumor is favorable,…”
Get full text

Histotype-specific analysis of acid ceramidase expression in ovarian cancer by El-Balat, Ahmed, Karn, Thomas, Holtrich, Uwe, Becker, Sven, Kommoss, Stefan, Győrffy, Balázs, Anglesio, Michael S., Huntsman, David G., Drosos, Zacharias, Rody, Achim, Gevensleben, Heidrun, Hanker, Lars C.

“…Acid ceramidase (ASAH1) is a key player in sphingolipid metabolism and signaling. It has prognostic value for several cancers, but histotype-specific analyses…”
Get full text

Subtype-specific mutation of PPP2R1A in endometrial and ovarian carcinomas by McConechy, Melissa K, Anglesio, Michael S, Kalloger, Steve E, Yang, Winnie, Senz, Janine, Chow, Christine, Heravi-Moussavi, Alireza, Morin, Gregg B, Mes-Masson, Anne-Marie, Carey, Mark S, McAlpine, Jessica N, Kwon, Janice S, Prentice, Leah M, Boyd, Niki, Shah, Sohrab P, Gilks, C. Blake, Huntsman, David G

“…PPP2R1A mutations have recently been described in 3/42 (7%) of clear cell carcinomas of the ovary. PPP2R1A encodes the α-isoform of the scaffolding subunit of…”
Get full text

BAF250a Expression in Atypical Endometriosis and Endometriosis-Associated Ovarian Cancer by Stamp, John P, Gilks, C Blake, Wesseling, Martine, Eshragh, Sima, Ceballos, Kathy, Anglesio, Michael S, Kwon, Janice S, Tone, Alicia, Huntsman, David G, Carey, Mark S

“…Atypical endometriosis (AE) is thought to be a precursor lesion to the ovarian cancer subtypes associated with endometriosis, namely, endometrioid and clear…”
Get more information

Akt-Mediated YB-1 Phosphorylation Activates Translation of Silent mRNA Species by Evdokimova, Valentina, Ruzanov, Peter, Anglesio, Michael S., Sorokin, Alexey V., Ovchinnikov, Lev P., Buckley, Jonathan, Triche, Timothy J., Sonenberg, Nahum, Sorensen, Poul H. B.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Single-Patient Molecular Testing with NanoString nCounter Data Using a Reference-Based Strategy for Batch Effect Correction by Talhouk, Aline, Kommoss, Stefan, Mackenzie, Robertson, Cheung, Martin, Leung, Samuel, Chiu, Derek S, Kalloger, Steve E, Huntsman, David G, Chen, Stephanie, Intermaggio, Maria, Gronwald, Jacek, Chan, Fong C, Ramus, Susan J, Steidl, Christian, Scott, David W, Anglesio, Michael S

“…A major weakness in many high-throughput genomic studies is the lack of consideration of a clinical environment where one patient at a time must be evaluated…”
Get full text

Selection of endometrial carcinomas for p53 immunohistochemistry based on nuclear features by Kang, Eun Young, Wiebe, Nicholas JP, Aubrey, Christa, Lee, Cheng‐Han, Anglesio, Michael S, Tilley, Derek, Ghatage, Prafull, Nelson, Gregg S, Lee, Sandra, Köbel, Martin

“…The World Health Organization endorses molecular subclassification of endometrial endometrioid carcinomas (EECs). Our objectives were to test the sensitivity…”
Get full text