Search Results - "ANGLARD, Patrick"

CDKL5 is a brain MeCP2 target gene regulated by DNA methylation by Carouge, Delphine, Host, Lionel, Aunis, Dominique, Zwiller, Jean, Anglard, Patrick

“…Abstract Rett syndrome and its “early-onset seizure” variant are severe neurodevelopmental disorders associated with mutations within the MECP2 and the CDKL5…”
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Fluoxetine and cocaine induce the epigenetic factors MeCP2 and MBD1 in adult rat brain by Cassel, Suzanne, Carouge, Delphine, Gensburger, Claire, Anglard, Patrick, Burgun, Claude, Dietrich, Jean-Bernard, Aunis, Dominique, Zwiller, Jean

“…Once bound to methylated CpG sites, methyl-CpG-binding protein 2 (MeCP2) is thought to silence transcription of downstream genes by recruiting a histone…”
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Matrix Metalloproteinases Are Differentially Expressed in Adipose Tissue during Obesity and Modulate Adipocyte Differentiation by Chavey, Carine, Mari, Bernard, Monthouel, Marie-Noëlle, Bonnafous, Stéphanie, Anglard, Patrick, Van Obberghen, Emmanuel, Tartare-Deckert, Sophie

“…Matrix metalloproteinases (MMPs) are essential for proper extracellular matrix remodeling, a process that takes place during obesity-mediated adipose tissue…”
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Red wine polyphenolic compounds strongly inhibit pro-matrix metalloproteinase-2 expression and its activation in response to thrombin via direct inhibition of membrane type 1-matrix metalloproteinase in vascular smooth muscle cells by Oak, Min-Ho, El Bedoui, Jasser, Anglard, Patrick, Schini-Kerth, Valérie B

“…Regular consumption of moderate amounts of red wine is associated with a reduced risk of coronary disease. Matrix metalloproteinases (MMPs) that participate in…”
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Alternative Splicing and Promoter Usage Generates an Intracellular Stromelysin 3 Isoform Directly Translated as an Active Matrix Metalloproteinase by Luo, Daochun, Mari, Bernard, Stoll, Isabelle, Anglard, Patrick

“…Human stromelysin 3 (ST3) is a matrix metalloproteinase (MMP) that has been implicated in cancer progression and in various tissue remodeling processes. Unlike…”
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Rat liver injury following normothermic ischemia is prevented by a phosphinic matrix metalloproteinase inhibitor by Cursio, Raffaele, Mari, Bernard, Louis, Krystel, Rostagno, Philippe, Saint-Paul, Marie-Christine, Giudicelli, Jean, Bottero, Virginie, Anglard, Patrick, Yiotakis, Athanasios, Dive, Vincent, Gugenheim, Jean, Auberger, Patrick

“…Hepatic ischemia occurs in liver transplantation, hemodynamic or cardiogenic shock, and liver resection associated with trauma or tumor. Ischemia/reperfusion…”
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Tumor Cell-mediated Induction of the Stromal Factor Stromelysin-3 Requires Heterotypic Cell Contact-dependent Activation of Specific Protein Kinase C Isoforms by Louis, Krystel, Guérineau, Nathalie, Fromigué, Olivia, Defamie, Virginie, Collazos, Alejandra, Anglard, Patrick, Shipp, Margaret A., Auberger, Patrick, Joubert, Dominique, Mari, Bernard

“…Stromelysin-3 (ST3, MMP-11) has been shown to be strongly overexpressed in stromal fibroblasts of most invasive human carcinomas. However, the molecular…”
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Epigenetic Regulation of Circadian Clocks and Its Involvement in Drug Addiction by Saad, Lamis, Zwiller, Jean, Kalsbeek, Andries, Anglard, Patrick

“…Based on studies describing an increased prevalence of addictive behaviours in several rare sleep disorders and shift workers, a relationship between circadian…”
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Multiple Regulatory Elements in the Murine Stromelysin-3 Promoter by Ludwig, Marie-Gabrielle, Basset, Paul, Anglard, Patrick

“…Stromelysin-3 (ST3) belongs to the matrix metalloproteinase (MMPs) family, a protease family involved in tissue remodeling. Although this family of enzymes is…”
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Structure and Promoter Characterization of the Human Stromelysin-3 Gene (∗) by Anglard, Patrick, Melot, Thomas, Guérin, Eric, Thomas, Gilles, Basset, Paul

“…In the present study, we have isolated the human stromelysin-3 (ST3) gene which encodes a matrix metalloproteinase (MMP) expressed in fibroblastic cells of…”
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Rhythmic Regulation of DNA Methylation Factors and Core-Clock Genes in Brain Structures Activated by Cocaine or Sucrose: Potential Role of Chromatin Remodeling by Saad, Lamis, Kalsbeek, Andries, Zwiller, Jean, Anglard, Patrick

“…The circadian system interacts with the mesocorticolimbic reward system to modulate reward and memory in a time-of-day dependent manner. The circadian…”
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Regulation of Brain DNA Methylation Factors and of the Orexinergic System by Cocaine and Food Self-Administration by Saad, Lamis, Sartori, Maxime, Pol Bodetto, Sarah, Romieu, Pascal, Kalsbeek, Andries, Zwiller, Jean, Anglard, Patrick

“…Inhibitors of DNA methylation and orexin type-1 receptor antagonists modulate the neurobiological effects driving drugs of abuse and natural reinforcers by…”
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Stromelysin-3: a paradigm for stroma-derived factors implicated in carcinoma progression by Basset, Paul, Bellocq, Jean-Pierre, Lefebvre, Olivier, Noël, Agnès, Chenard, Marie-Pierre, Wolf, Catherine, Anglard, Patrick, Rio, Marie-Christine

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Cocaine represses protein phosphatase-1Cβ through DNA methylation and Methyl-CpG Binding Protein-2 recruitment in adult rat brain by Pol Bodetto, Sarah, Carouge, Delphine, Fonteneau, Mathieu, Dietrich, Jean-Bernard, Zwiller, Jean, Anglard, Patrick

“…Repeated cocaine exposure induces epigenetic factors such as DNA methyl-binding proteins, indicating that resulting changes in gene expression are mediated by…”
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Transcriptional Induction of Stromelysin-3 in Mesodermal Cells Is Mediated by an Upstream CCAAT/Enhancer-binding Protein Element Associated with a DNase I-hypersensitive Site by Luo, D, Guérin, E, Ludwig, M G, Stoll, I, Basset, P, Anglard, P

“…Stromelysin-3 (ST3) is a matrix metalloproteinase whose synthesis is markedly increased in stromal fibroblasts of most invasive human carcinomas. In the…”
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Stromelysin-3 Induction and Interstitial Collagenase Repression by Retinoic Acid by Eric Guérin, Marie-Gabrielle Ludwig, Paul Basset, Patrick Anglard

“…Human stromelysin-3 and interstitial collagenase are matrix metalloproteinases whose expression by stromal cells in several types of carcinomas has been…”
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Differential regulation of MeCP2 and PP1 in passive or voluntary administration of cocaine or food by Pol Bodetto, Sarah, Romieu, Pascal, Sartori, Maxime, Tesone-Coelho, Carolina, Majchrzak, Monique, Barbelivien, Alexandra, Zwiller, Jean, Anglard, Patrick

“…Cocaine exposure induces changes in the expression of numerous genes, in part through epigenetic modifications. We have initially shown that cocaine increases…”
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Cocaine represses protein phosphatase-1CI2 through DNA methylation and Methyl-CpG Binding Protein-2 recruitment in adult rat brain by Bodetto, Sarah, Carouge, Delphine, Fonteneau, Mathieu, Dietrich, Jean-Bernard, Zwiller, Jean, Anglard, Patrick

“…Repeated cocaine exposure induces epigenetic factors such as DNA methyl-binding proteins, indicating that resulting changes in gene expression are mediated by…”
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Histone deacetylase inhibitors upregulate MMP11 gene expression through Sp1/Smad complexes in human colon adenocarcinoma cells by Barrasa, Juan I., Olmo, Nieves, Santiago-Gómez, Angélica, Lecona, Emilio, Anglard, Patrick, Turnay, Javier, Lizarbe, M. Antonia

“…MMP-11 (stromelysin-3) is a matrix metalloproteinase associated with tumor progression and poor prognosis. Its expression was initially described exclusively…”
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Inhibition of histone deacetylases in rats self-administering cocaine regulates lissencephaly gene-1 and reelin gene expression, as revealed by microarray technique by Host, Lionel, Anglard, Patrick, Romieu, Pascal, Thibault, Christelle, Dembele, Doulaye, Aunis, Dominique, Zwiller, Jean

“…J. Neurochem. (2010) 10.1111/j.1471-4159.2010.06591.x Injection of the histone deacetylase inhibitor trichostatin A (TsA) to rats has been shown to decrease…”
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