Search Results - "ANGELOSANTO, Jill M"
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Network Analysis Reveals Centrally Connected Genes and Pathways Involved in CD8+ T Cell Exhaustion versus Memory
Published in Immunity (Cambridge, Mass.) (14-12-2012)“…Exhausted CD8+ T cells function poorly and are negatively regulated by inhibitory receptors. Transcriptional profiling has identified gene expression changes…”
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Molecular and Transcriptional Basis of CD4+ T Cell Dysfunction during Chronic Infection
Published in Immunity (Cambridge, Mass.) (20-02-2014)“…T cell exhaustion is common during chronic infections. Although CD4+ T cells are critical for controlling viral load during chronic viral infections, less is…”
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Progressive Loss of Memory T Cell Potential and Commitment to Exhaustion during Chronic Viral Infection
Published in Journal of Virology (01-08-2012)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Cooperativity between CD8+ T cells, non-neutralizing antibodies, and alveolar macrophages is important for heterosubtypic influenza virus immunity
Published in PLoS pathogens (01-03-2013)“…Seasonal epidemics of influenza virus result in ∼36,000 deaths annually in the United States. Current vaccines against influenza virus elicit an antibody…”
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5
Innate lymphoid cells regulate CD4+ T-cell responses to intestinal commensal bacteria
Published in Nature (London) (06-06-2013)“…Group 3 innate lymphoid cells are shown to process and present antigen and to control CD4 + T-cell responses to intestinal commensal bacteria through an…”
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Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus
Published in Nature immunology (01-11-2011)“…Cytokine-producing innate lymphoid cells are found at mucosal surfaces. Artis and Wherry and their colleagues show that innate 'nuocyte-like' cells accumulate…”
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A Role for the Transcriptional Repressor Blimp-1 in CD8+ T Cell Exhaustion during Chronic Viral Infection
Published in Immunity (Cambridge, Mass.) (21-08-2009)“…T cell exhaustion is common during chronic infections and can prevent optimal immunity. Although recent studies have demonstrated the importance of inhibitory…”
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Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virus-specific CD8+ T cell responses during chronic infection
Published in Nature immunology (29-05-2011)“…The transcriptional control of T cell exhaustion remains unclear. Wherry and colleagues show that the transcription factor T-bet regulates CD8 + T cell…”
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Transcription factor regulation of CD8+ T-cell memory and exhaustion
Published in Immunological reviews (01-07-2010)“…During an infection, antigen‐specific CD8+ T cells undergo numerous cellular and transcriptional changes as they develop from naive T cells into effector and…”
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10
Serotonin induces pulmonary artery smooth muscle cell migration
Published in Biochemical pharmacology (12-01-2006)“…The chronic phase of pulmonary arterial hypertension (PAH) is associated with vascular remodeling, especially thickening of the smooth muscle layer of large…”
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Transcription factor regulation of CD8+ T-cell memory and exhaustion: Terminating the Immune Response
Published in Immunological reviews (2010)Get full text
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Cooperativity Between CD8+ T Cells, Non-Neutralizing Antibodies, and Alveolar Macrophages Is Important for Heterosubtypic Influenza Virus Immunity: e1003207
Published in PLoS pathogens (01-03-2013)“…Seasonal epidemics of influenza virus result in ~36,000 deaths annually in the United States. Current vaccines against influenza virus elicit an antibody…”
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13
Innate lymphoid cells regulate CD4^sup +^ T-cell responses to intestinal commensal bacteria
Published in Nature (London) (06-06-2013)“…Innate lymphoid cells (ILCs) are a recently characterized family of immune cells that have critical roles in cytokine-mediated regulation of intestinal…”
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Innate lymphoid cells regulate [CD4.sup.+] T-cell responses to intestinal commensal bacteria
Published in Nature (London) (06-06-2013)Get full text
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15
Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virus-specific [CD8.sup.+] T cell responses during chronic infection
Published in Nature immunology (01-07-2011)“…T cell exhaustion has a major role in failure to control chronic infection. High expression of inhibitory receptors, including PD-1, and the inability to…”
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Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virus-specific CD8 super(+) T cell responses during chronic infection
Published in Nature immunology (20-06-2011)“…T cell exhaustion has a major role in failure to control chronic infection. High expression of inhibitory receptors, including PD-1, and the inability to…”
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Journal Article -
17
T-bet represses expression of PD-1 and sustains virus-specific CD8 T cell responses during chronic infection
Published in Nature immunology (29-05-2011)“…T cell exhaustion plays a major role in failure to control chronic infections. High expression of inhibitory receptors, including PD-1, and the inability to…”
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Journal Article -
18
Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus
Published in Nature immunology (01-11-2011)“…Innate lymphoid cells (ILCs), a heterogeneous cell population, are critical in orchestrating immunity and inflammation in the intestine, but whether ILCs…”
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19
Innate lymphoid cells promote lung tissue homeostasis following acute influenza virus infection
Published in Nature immunology (01-11-2011)“…Innate lymphoid cells (ILCs), a recently identified heterogeneous cell population, are critical in orchestrating immunity and inflammation in the intestine but…”
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Journal Article -
20
Progressive loss of memory T cell potential and commitment to exhaustion during chronic viral infection
Published 01-01-2012“…During an acute infection, activated CD8 T cells undergo a process of differentiation from naïve to cytotoxic effector cells and finally to antigen experienced…”
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