Search Results - "ANGELES, Jose Ma. M."
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Behind Enemy Lines: Immunomodulatory Armamentarium of the Schistosome Parasite
Published in Frontiers in immunology (09-06-2020)“…The deeply rooted, intricate relationship between the parasite and the human host has enabled the parasite to successfully survive within the host and…”
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Schistosoma japonicum cathepsin B as potential diagnostic antigen for Asian zoonotic schistosomiasis
Published in Parasitology research (1987) (01-09-2019)“…In this study, the diagnostic value of Schistosoma japonicum cathepsin B (SjCatB) was evaluated as an antigen for the early detection of S. japonicum…”
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Current advances in serological and molecular diagnosis of Schistosoma mekongi infection
Published in Tropical medicine and health (22-04-2024)“…Schistosomiasis, a neglected tropical disease, caused by blood flukes belonging to the genus Schistosoma; it persists as a public health problem in selected…”
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Analyses of the expression, immunohistochemical properties and serodiagnostic potential of Schistosoma japonicum peroxiredoxin-4
Published in Parasites & vectors (01-09-2020)“…Schistosoma japonicum, which inhabits the mesenteric vein of the mammalian hosts for about 20 to 30 years, is subjected to the oxidative stresses from the host…”
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Utilization of ELISA using thioredoxin peroxidase-1 and tandem repeat proteins for diagnosis of Schistosoma japonicum infection among water buffaloes
Published in PLoS neglected tropical diseases (01-08-2012)“…The presence of animal reservoirs in Schistosoma japonicum infection has been a major obstacle in the control of schistosomiasis. Previous studies have proven…”
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Evaluation of Crude and Recombinant Antigens of Schistosoma japonicum for the Detection of Schistosoma mekongi Human Infection
Published in Diagnostics (Basel) (04-01-2023)“…Asian schistosomiasis caused by the blood fluke is endemic in northern Cambodia and Southern Lao People's Democratic Republic. The disease is mainly diagnosed…”
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Geographic strain differentiation of Schistosoma japonicum in the Philippines using microsatellite markers
Published in PLoS neglected tropical diseases (10-07-2017)“…Microsatellites have been found to be useful in determining genetic diversities of various medically-important parasites which can be used as basis for an…”
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Cloning, Expression and Evaluation of Thioredoxin Peroxidase-1 Antigen for the Serological Diagnosis of Schistosoma mekongi Human Infection
Published in Diagnostics (Basel) (07-12-2022)“…, a blood fluke that causes Asian zoonotic schistosomiasis, is distributed in communities along the Mekong River in Cambodia and Lao People's Democratic…”
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Plasmodium knowlesi thioredoxin peroxidase 1 binds to nucleic acids and has RNA chaperone activity
Published in Parasitology research (1987) (01-11-2014)“…Malaria parasites are under oxidative attack throughout their life cycle in human body and mosquito vector. Therefore, Plasmodium antioxidant defenses are…”
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Development and optimization of cocktail-ELISA for a unified surveillance of zoonotic schistosomiasis in multiple host species
Published in Parasitology research (1987) (01-03-2015)“…The zoonotic characteristic of the human parasite Schistosoma japonicum infecting a significant number of wild and domestic animals highlights the need to…”
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Detection of canine Schistosoma japonicum infection using recombinant thioredoxin peroxidase-1 and tandem repeat proteins
Published in Journal of Veterinary Medical Science (2019)“…Humans and dogs live very close together and share various pathogens causing zoonotic parasitoses like schistosomiasis. A previous population genetics study…”
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Effect of thioredoxin peroxidase-1 gene disruption on the liver stages of the rodent malaria parasite Plasmodium berghei
Published in Parasitology international (01-06-2015)“…Abstract Phenotypic observation of thioredoxin peroxidase-1 (TPx-1) gene-disrupted Plasmodium berghei (TPx-1 KO) in the liver-stage was performed with an in…”
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Field Evaluation of Recombinant Antigen ELISA in Detecting Zoonotic Schistosome Infection Among Water Buffaloes in Endemic Municipalities in the Philippines
Published in Frontiers in veterinary science (15-10-2020)“…In this study, we investigated the use of recombinant antigens thioredoxin peroxidase-1 (rSjTPx-1) and tandem repeat rSj1TR in evaluating the antibody…”
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Evaluation of Schistosoma japonicum thioredoxin peroxidase-1 as a potential circulating antigen target for the diagnosis of Asian schistosomiasis
Published in Journal of Veterinary Medical Science (01-01-2018)“…Asian schistosomiasis caused by Schistosoma japonicum is a serious zoonotic disease endemic in China, the Philippines and parts of Indonesia. Mass drug…”
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Cloning and characterization of Plasmodium vivax thioredoxin peroxidase-1
Published in Parasitology research (1987) (01-08-2012)“…Reactive oxygen species produced from hemoglobin digestion and the host immune system could have adverse effects on malaria parasites. To protect themselves,…”
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Plasmodium vivax and Plasmodium knowlesi: Cloning, expression and functional analysis of 1-Cys peroxiredoxin
Published in Experimental parasitology (01-01-2013)“…[Display omitted] ► 1-Cys-Prx from Plasmodium vivax and P. knowlesi was cloned and characterized. ► Functional studies showed that recombinant 1-Cys-Prx had…”
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Expression profiles of peroxiredoxins in liver stage of the rodent malaria parasite Plasmodium berghei
Published in Parasitology international (01-06-2013)“…Abstract mRNA and protein expression profiles for three peroxiredoxins (TPx-1, TPx-2 and 1-Cys Prx) of liver stage Plasmodium berghei were examined through…”
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Water buffalo as sentinel animals for schistosomiasis surveillance
Published in Bulletin of the World Health Organization (01-07-2015)“…About 75% of human pathogens are zoonotic, meaning that they are communicated from animals to humans. Cattle, water buffalo, goats, dogs, pigs and rats are…”
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Utilization of real time PCR for the assessment of egg burden in the organs of Schistosoma japonicum experimentally infected mice
Published in Experimental parasitology (01-06-2018)“…Schistosoma japonicum, causing zoonotic intestinal schistosomiasis, is found in China, the Philippines and parts of Indonesia. Severe disease manifestations…”
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Development of Monoclonal Antibodies That Target 1-Cys Peroxiredoxin and Differentiate Plasmodium falciparum from P. vivax and P. knowlesi
Published in Tropical Medicine and Health (2013)“…Prompt and accurate diagnosis of malarial patients is a crucial factor in controlling the morbidity and mortality of the disease. Effective treatment decisions…”
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