Search Results - "ANDRES, J. P"

Influence of Affinity and Antigen Internalization on the Uptake and Penetration of Anti-HER2 Antibodies in Solid Tumors by RUDNICK, Stephen I, JIANLONG LOU, SHALLER, Calvin C, YONG TANG, KLEIN-SZANTO, Andres J. P, WEINER, Louis M, MARKS, James D, ADAMS, Gregory P

“…Antibody drugs are widely used in cancer therapy, but conditions to maximize tumor penetration and efficacy have yet to be fully elucidated. In this study, we…”
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Correction to: Overexpression of the HMGA2 gene in transgenic mice leads to the onset of pituitary adenomas by Fedele, Monica, Battista, Sabrina, Kenyon, Lawrence, Baldassarre, Gustavo, Fidanza, Vincenzo, Klein-Szanto, Andres J. P., Parlow, A. F., Visone, Rosa, Pierantoni, Giovanna M., Outwater, Eric, Santoro, Massimo, Croce, Carlo M., Fusco, Alfredo

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p21-Activated Kinase 1 Is Required for Efficient Tumor Formation and Progression in a Ras-Mediated Skin Cancer Model by HOI YEE CHOW, JUBB, Adrian M, SILVIO GUTKIND, J, HOEFLICH, Klaus P, CHERNOFF, Jonathan, KOCH, Jennifer N, JAFFER, Zahara M, STEPANOVA, Dina, CAMPBELL, David A, DURON, Sergio G, O'FARRELL, Marie, CAI, Kathy Q, KLEIN-SZANTO, Andres J. P

“…The RAS genes are the most commonly mutated oncogenes in human cancer and present a particular therapeutic dilemma, as direct targeting of Ras proteins by…”
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Increased expression of stem cell markers in malignant melanoma by Klein, Walter M, Wu, Bryan P, Zhao, Shuping, Wu, Hong, Klein-Szanto, Andres J P, Tahan, Steven R

“…The potential role of stem cells in neoplasia is a subject of recent interest. Three markers of melanocytic stem cells have been described recently. CD166 is…”
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Phase II Study of Erlotinib in Patients With Malignant Pleural Mesothelioma: A Southwest Oncology Group Study by GARLAND, Linda L, RANKIN, Cathryn, GANDARA, David R, RIVKIN, Saul E, SCOTT, Katherine M, NAGLE, Raymond B, KLEIN-SZANTO, Andres J. P, TESTA, Joseph R, ALTOMARE, Deborah A, BORDEN, Ernest C

“…Malignant pleural mesothelioma (MPM) expresses high levels of epidermal growth factor receptor (EGFR), and preclinical studies have identified antitumor…”
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Hypoxia activates the cyclooxygenase-2–prostaglandin E synthase axis by Lee, James J., Natsuizaka, Mitsuteru, Ohashi, Shinya, Wong, Gabrielle S., Takaoka, Munenori, Michaylira, Carmen Z., Budo, Daniela, Tobias, John W., Kanai, Michiyuki, Shirakawa, Yasuhiro, Naomoto, Yoshio, Klein-Szanto, Andres J.P., Haase, Volker H., Nakagawa, Hiroshi

“…Hypoxia-inducible factors (HIFs), in particular HIF-1α, have been implicated in tumor biology. However, HIF target genes in the esophageal tumor…”
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The Fbx4 Tumor Suppressor Regulates Cyclin D1 Accumulation and Prevents Neoplastic Transformation by Vaites, Laura Pontano, Lee, Eric K., Lian, Zhaorui, Barbash, Olena, Roy, Darshan, Wasik, Mariusz, Klein-Szanto, Andres J. P., Rustgi, Anil K., Diehl, J. Alan

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Transgenic mice overexpressing the wild-type form of the HMGA1 gene develop mixed growth hormone/prolactin cell pituitary adenomas and natural killer cell lymphomas by FEDELE, Monica, PENTIMALLI, Francesca, VIGLIETTO, Giuseppe, CROCE, Carlo M, FUSCO, Alfredo, BALDASSARRE, Gustavo, BATTISTA, Sabrina, KLEIN-SZANTO, Andres J. P, KENYON, Lawrence, VISONE, Rosa, DE MARTINO, Ivana, CIARMIELLO, Andrea, ARRA, Claudio

“…Overexpression of HMGA1 proteins is a constant feature of human carcinomas. Moreover, rearrangements of this gene have been detected in several human benign…”
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Nuclear accumulation of cyclin D1 during S phase inhibits Cul4-dependent Cdt1 proteolysis and triggers p53-dependent DNA rereplication by Aggarwal, Priya, Lessie, Matthew D, Lin, Douglas I, Pontano, Laura, Gladden, Andrew B, Nuskey, Beth, Goradia, Ami, Wasik, Mariusz A, Klein-Szanto, Andres J P, Rustgi, Anil K, Bassing, Craig H, Diehl, J Alan

“…Deregulation of cyclin D1 occurs in numerous human cancers through mutations, alternative splicing, and gene amplification. Although cancer-derived cyclin D1…”
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Analysis of the MRP4 Drug Resistance Profile in Transfected NIH3T3 Cells by Lee, Kun, Klein-Szanto, Andres J. P., Kruh, Gary D.

“…Background: Multidrug resistance-associated protein (MRP) 1 and canalicular multispecific organic anion transporter (cMOAT or MRP2) are adenosine…”
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A single treatment of yttrium-90-labeled CHX-A-c6.5 diabody inhibits the growth of established human tumor xenografts in immunodeficient mice by ADAMS, Gregory P, SHALLER, Calvin C, DADACHOVA, Ekaterina, SIMMONS, Heidi H, HORAK, Eva M, TESFAYE, Abohawariat, KLEIN-SZANTO, Andres J. P, MARKS, James D, BRECHBIEL, Martin W, WEINER, Louis M

“…Antitumor diabody molecules are noncovalent single-chain Fv dimers that recapitulate the divalent binding properties of native IgG antibodies. Diabodies are…”
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Psychosocial functioning and vascular endothelial growth factor in patients with head and neck cancer by Fang, Carolyn Y., Egleston, Brian L., Ridge, John A., Lango, Miriam N., Bovbjerg, Dana H., Studts, Jamie L., Burtness, Barbara A., Einarson, Margret B., Klein-Szanto, Andres J. P.

“…Background Psychosocial functioning is associated with vascular endothelial growth factor (VEGF) in various patient populations. This study examined whether…”
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Overexpression of the HMGA2 gene in transgenic mice leads to the onset of pituitary adenomas by FEDELE, Monica, BATTISTA, Sabrina, SANTORO, Massimo, CROCE, Carlo M, FUSCO, Alfredo, KENYON, Lawrence, BALDASSARRE, Gustavo, FIDANZA, Vincenzo, KLEIN-SZANTO, Andres J. P, PARLOW, A. F, VISONE, Rosa, PIERANTONI, Giovanna M, OUTWATER, Eric

“…Overexpression of the HMGA2 gene is a common feature of neoplastic cells both in experimental and human models. Intragenic and extragenic HMGA2 rearrangements…”
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Keep recycling going: New approaches to reduce LDL-C by Klein-Szanto, Andres J.P., Bassi, Daniel E.

“…[Display omitted] Hypercholesterolemia represents a leading cause in the development of atherosclerotic plaques, increasing the risk for ACVS. It actually…”
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VILIP-1 expression in vivo results in decreased mouse skin keratinocyte proliferation and tumor development by Fu, Jian, Jin, Fang, Zhang, Jirong, Fong, Kathryn, Bassi, Daniel E, Lopez De Cicco, Ricardo, Ramaraju, Divya, Braunewell, Karl-Heinz, Conti, Claudio, Benavides, Fernando, Klein-Szanto, Andres J P

“…VILIP-1, a member of the neuronal Ca(2+) sensor protein family, is able to act as a tumor suppressor in carcinoma cells by inhibiting cell proliferation and…”
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Biomechanical Remodeling of the Microenvironment by Stromal Caveolin-1 Favors Tumor Invasion and Metastasis by Goetz, Jacky G., Minguet, Susana, Navarro-Lérida, Inmaculada, Lazcano, Juan José, Samaniego, Rafael, Calvo, Enrique, Tello, Marta, Osteso-Ibáñez, Teresa, Pellinen, Teijo, Echarri, Asier, Cerezo, Ana, Klein-Szanto, Andres J.P., Garcia, Ricardo, Keely, Patricia J., Sánchez-Mateos, Paloma, Cukierman, Edna, Del Pozo, Miguel A.

“…Mechanotransduction is a key determinant of tissue homeostasis and tumor progression. It is driven by intercellular adhesions, cell contractility, and forces…”
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Haploinsufficiency of the Hmga1 gene causes cardiac hypertrophy and myelo-lymphoproliferative disorders in mice by FEDELE, Monica, FIDANZA, Vincenzo, BALDASSARRE, Gustavo, ARRA, Claudio, VIGLIETTO, Giuseppe, INDOLFI, Ciro, CROCE, Carlo M, FUSCO, Alfredo, BATTISTA, Sabrina, PENTIMALLI, Francesca, KLEIN-SZANTO, Andres J. P, VISONE, Rosa, DE MARTINO, Ivana, CURCIO, Antonio, MORISCO, Carmine, DEL VECCHIO, Luigi

“…The HMGA1 protein is a major factor in chromatin architecture and gene control. It plays a critical role in neoplastic transformation. In fact, blockage of…”
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Prognostic Value of Histological Grading in Noninflammatory Canine Mammary Carcinomas in a Prospective Study With Two-Year Follow-Up: Relationship With Clinical and Histological Characteristics by Peña, L., Andrés, P. J. De, Clemente, M., Cuesta, P., Pérez-Alenza, M. D.

“…In this prospective study, a canine-adapted histological grading method was compared with histopathological and clinical characteristics and was evaluated as a…”
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Tumorigenic conversion of primary human esophageal epithelial cells using oncogene combinations in the absence of exogenous ras by KIM, Seok-Hyun, NAKAGAWA, Hiroshi, NAVARAJ, Arunasalam, NAOMOTO, Yoshio, KLEIN-SZANTO, Andres J. P, RUSTGI, Anil K, EL-DEIRY, Wafik S

“…To investigate pathways of human esophageal squamous cell transformation, we generated esophageal tumor cells using human telomerase- and SV40-immortalized…”
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Canine cell line, IPC‐366, as a good model for the study of inflammatory breast cancer by Caceres, S., Peña, L., Lacerda, L., Illera, M. J., de Andres, P. J., Larson, R. A., Gao, H., Debeb, B. G., Woodward, W. A., Reuben, J. M., Illera, J. C.

“…Inflammatory breast cancer (IBC) is an aggressive type of cancer with poor survival in women. Inflammatory mammary cancer (IMC) in dogs is very similar to…”
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