Search Results - "ANDREEN, Lotta"
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Treatment of premenstrual dysphoric disorder with the GABA A receptor modulating steroid antagonist Sepranolone (UC1010)-A randomized controlled trial
Published in Psychoneuroendocrinology (01-06-2017)“…Allopregnanolone is a metabolite from progesterone and a positive modulator of the GABA receptor. This endogenous steroid may induce negative mood in sensitive…”
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Relationship between allopregnanolone and negative mood in postmenopausal women taking sequential hormone replacement therapy with vaginal progesterone
Published in Psychoneuroendocrinology (01-02-2005)“…Objective: To compare severity of negative mood and physical symptoms between women with different progesterone, allopregnanolone, and pregnanolone plasma…”
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The role of hormones and hormonal treatments in premenstrual syndrome
Published in CNS drugs (2003)“…Premenstrual syndrome (PMS) is a menstrual cycle-linked condition with both mental and physical symptoms. Most women of fertile age experience cyclical changes…”
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4
Progesterone effects during sequential hormone replacement therapy
Published in European journal of endocrinology (01-05-2003)“…OBJECTIVE: The aim was to investigate the effect on mood and the physical symptoms of two dosages of natural progesterone and a placebo in postmenopausal women…”
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Sex steroid induced negative mood may be explained by the paradoxical effect mediated by GABAA modulators
Published in Psychoneuroendocrinology (01-09-2009)“…Summary Certain women experience negative mood symptoms as a result of progesterone during the luteal phase of the menstrual cycle, progestagens in hormonal…”
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Tolerance to allopregnanolone with focus on the GABA‐A receptor
Published in British journal of pharmacology (01-01-2011)“…Many studies have suggested a relationship between stress, sex steroids, and negative mental and mood changes in humans. The progesterone metabolite…”
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Allopregnanolone concentration and mood- : a bimodal association in postmenopausal women treated with oral progesterone
Published in Psychopharmacologia (01-08-2006)“…Allopregnanolone effects on mood in postmenopausal women are unclear thus far. Allopregnanolone is a neuroactive steroid with contradictory effects…”
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Effects of Roux-en-Y gastric bypass surgery on eating behaviour and allopregnanolone levels in obese women with polycystic ovary syndrome
Published in Gynecological endocrinology (01-04-2015)“…Abstract Polycystic ovary syndrome (PCOS) is associated with abnormal eating habits. We examined whether surgical treatment affected allopregnanolone levels…”
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Paradoxical effects of GABA-A modulators may explain sex steroid induced negative mood symptoms in some persons
Published in Neuroscience (15-09-2011)“…Abstract Some women have negative mood symptoms, caused by progestagens in hormonal contraceptives or sequential hormone therapy or by progesterone in the…”
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Sex steroid induced negative mood may be explained by the paradoxical effect mediated by GABA sub(A) modulators
Published in Psychoneuroendocrinology (01-09-2009)“…Certain women experience negative mood symptoms as a result of progesterone during the luteal phase of the menstrual cycle, progestagens in hormonal…”
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Treatment of premenstrual dysphoric disorder with the GABAA receptor modulating steroid antagonist Sepranolone (UC1010)—A randomized controlled trial
Published in Psychoneuroendocrinology (01-06-2017)“…Highlights • Sepranolone (UC1010) is a GABAA modulating steroid antagonist to the progesterone metabolite allopregnanolone, which is probably causing the…”
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12
ALCOHOL AND NEUROACTIVE STEROID INTERACTIONS IN THE MENSTRUAL CYCLE
Published in Alcoholism, clinical and experimental research (01-08-2004)Get full text
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13
Risk factors for lymphedema and method of assessment in endometrial cancer: a prospective longitudinal multicenter study
Published in International journal of gynecological cancer (01-11-2021)“…The aim of the study was to determine risk factors for lymphedema of the lower limbs, assessed by four methods, 1 year after surgery for endometrial cancer. A…”
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Pathogenesis in Menstrual Cycle-Linked CNS Disorders
Published in Annals of the New York Academy of Sciences (01-12-2003)“…: That 3alpha‐hydroxy‐5alpha/beta‐pregnane steroids (GABA steroids) have modulatory effects on the GABA‐A receptor is well known. In behavioral studies in…”
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Pharmacokinetics of progesterone and its metabolites allopregnanolone and pregnanolone after oral administration of low-dose progesterone
Published in Maturitas (20-06-2006)“…To investigate the pharmacokinetics of progesterone, allopregnanolone and pregnanolone after treatment with a low oral dose of progesterone. Eight…”
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