Search Results - "ANDES, David R"
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Candida-streptococcal interactions in biofilm-associated oral diseases
Published in PLoS pathogens (01-12-2018)“…[...]these mannoprotein-deficient mutants developed poor mixed-species biofilms with S. mutans, showed reduced EPS α-glucans content, and reduced microbial…”
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A Recently Evolved Transcriptional Network Controls Biofilm Development in Candida albicans
Published in Cell (20-01-2012)“…A biofilm is an organized, resilient group of microbes in which individual cells acquire properties, such as drug resistance, that are distinct from those…”
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Clinical Practice Guideline for the Management of Candidiasis: 2016 Update by the Infectious Diseases Society of America
Published in Clinical infectious diseases (15-02-2016)“…It is important to realize that guidelines cannot always account for individual variation among patients. They are not intended to supplant physician judgment…”
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Epidemiology and outcomes of invasive candidiasis due to non-albicans species of Candida in 2,496 patients: data from the Prospective Antifungal Therapy (PATH) registry 2004-2008
Published in PloS one (03-07-2014)“…This analysis describes the epidemiology and outcomes of invasive candidiasis caused by non-albicans species of Candida in patients enrolled in the Prospective…”
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Candida albicans biofilm-induced vesicles confer drug resistance through matrix biogenesis
Published in PLoS biology (01-10-2018)“…Cells from all kingdoms of life produce extracellular vesicles (EVs). Their cargo is protected from the environment by the surrounding lipid bilayer. EVs from…”
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Animal models in the pharmacokinetic/pharmacodynamic evaluation of antimicrobial agents
Published in Bioorganic & medicinal chemistry (15-12-2016)“…[Display omitted] Animal infection models in the pharmacokinetic/pharmacodynamic (PK/PD) evaluation of antimicrobial therapy serve an important role in…”
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Fungal Super Glue: The Biofilm Matrix and Its Composition, Assembly, and Functions
Published in PLoS pathogens (01-09-2016)“…[...]there are complex interactions among the matrix components. [...]certain cell wall production enzymes are important for the production of a matrix [12,13]…”
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Core Recommendations for Antifungal Stewardship: A Statement of the Mycoses Study Group Education and Research Consortium
Published in The Journal of infectious diseases (05-08-2020)“…Abstract In recent years, the global public health community has increasingly recognized the importance of antimicrobial stewardship (AMS) in the fight to…”
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The antimicrobial potential of Streptomyces from insect microbiomes
Published in Nature communications (31-01-2019)“…Antimicrobial resistance is a global health crisis and few novel antimicrobials have been discovered in recent decades. Natural products, particularly from…”
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Contributions of the Biofilm Matrix to Candida Pathogenesis
Published in Journal of fungi (Basel) (01-03-2020)“…In healthcare settings, spp. cause invasive disease with high mortality. The overwhelming majority of cases are associated with the use of critically-needed…”
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A Candida biofilm-induced pathway for matrix glucan delivery: implications for drug resistance
Published in PLoS pathogens (01-08-2012)“…Extracellular polysaccharides are key constituents of the biofilm matrix of many microorganisms. One critical carbohydrate component of Candida albicans…”
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Coordination of fungal biofilm development by extracellular vesicle cargo
Published in Nature communications (29-10-2021)“…The fungal pathogen Candida albicans can form biofilms that protect it from drugs and the immune system. The biofilm cells release extracellular vesicles (EVs)…”
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An expanded regulatory network temporally controls Candida albicans biofilm formation
Published in Molecular microbiology (01-06-2015)“…Summary Candida albicans biofilms are composed of highly adherent and densely arranged cells with properties distinct from those of free‐floating (planktonic)…”
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Role of Fks1p and Matrix Glucan in Candida albicans Biofilm Resistance to an Echinocandin, Pyrimidine, and Polyene
Published in Antimicrobial Agents and Chemotherapy (01-08-2010)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Bacterial Infections in the Stem Cell Transplant Recipient and Hematologic Malignancy Patient
Published in Infectious disease clinics of North America (01-06-2019)“…Bacteremia (bloodstream infection) is frequent (20%–30% incidence) in the stem cell transplant and hematologic malignancy population and often occurs in the…”
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Community participation in biofilm matrix assembly and function
Published in Proceedings of the National Academy of Sciences - PNAS (31-03-2015)“…Biofilms of the fungus Candida albicans produce extracellular matrix that confers such properties as adherence and drug resistance. Our prior studies indicate…”
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A small molecule produced by Lactobacillus species blocks Candida albicans filamentation by inhibiting a DYRK1-family kinase
Published in Nature communications (22-10-2021)“…The fungus Candida albicans is an opportunistic pathogen that can exploit imbalances in microbiome composition to invade its human host, causing pathologies…”
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Isavuconazole (BAL4815) Pharmacodynamic Target Determination in an In Vivo Murine Model of Invasive Pulmonary Aspergillosis against Wild-Type and cyp51 Mutant Isolates of Aspergillus fumigatus
Published in Antimicrobial Agents and Chemotherapy (01-12-2013)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Genetic Basis of Candida Biofilm Resistance Due to Drug-Sequestering Matrix Glucan
Published in The Journal of infectious diseases (01-07-2010)“…Medical devices provide an ecological niche for microbes to flourish as a biofilm community, protected from antimicrobials and host defenses. Biofilms formed…”
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Invasive Fungal Infections among Organ Transplant Recipients: Results of the Transplant-Associated Infection Surveillance Network (TRANSNET)
Published in Clinical infectious diseases (15-04-2010)“…Background. Invasive fungal infections (IFIs) are a major cause of morbidity and mortality among organ transplant recipients. Multicenter prospective…”
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