Search Results - "ANDERSSON, Kristin"

Prominent heart organ-level performance deficits in a genetic model of targeted severe and progressive SERCA2 deficiency by Heinis, Frazer I, Andersson, Kristin B, Christensen, Geir, Metzger, Joseph M

“…The cardiac SERCA2 Ca(2+) pump is critical for maintaining normal Ca(2+) handling in the heart. Reduced SERCA2a content and blunted Ca(2+) reuptake are…”
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Reference gene alternatives to Gapdh in rodent and human heart failure gene expression studies by Brattelid, Trond, Winer, Lisbeth H, Levy, Finn Olav, Liestøl, Knut, Sejersted, Ole M, Andersson, Kristin B

“…Quantitative real-time RT-PCR (RT-qPCR) is a highly sensitive method for mRNA quantification, but requires invariant expression of the chosen reference…”
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Long-term levosimendan treatment improves systolic function and myocardial relaxation in mice with cardiomyocyte-specific disruption of the Serca2 gene by Hillestad, Vigdis, Kramer, Frank, Golz, Stefan, Knorr, Andreas, Andersson, Kristin B, Christensen, Geir

“…In human heart failure (HF), reduced cardiac function has, at least partly, been ascribed to altered calcium homeostasis in cardiomyocytes. The effects of the…”
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Sodium accumulation promotes diastolic dysfunction in end-stage heart failure following Serca2 knockout by Louch, William E., Hougen, Karina, Mørk, Halvor K., Swift, Fredrik, Aronsen, Jan M., Sjaastad, Ivar, Reims, Henrik M., Roald, Borghild, Andersson, Kristin B., Christensen, Geir, Sejersted, Ole M.

“…Alterations in trans-sarcolemmal and sarcoplasmic reticulum (SR) Ca 2+ fluxes may contribute to impaired cardiomyocyte contraction and relaxation in heart…”
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Circulating cytokine levels in mice with heart failure are etiology dependent by VISTNES, Maria, WAEHRE, Anne, NYGARD, Ståle, SJAASTAD, Ivar, ANDERSSON, Kristin B, HUSBERG, Cathrine, CHRISTENSEN, Geir

“…The aim of this study was to examine whether alterations in circulating cytokine levels are dependent on the etiology of myocardial hypertrophy and heart…”
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Prospective Seroepidemiologic Study of Human Papillomavirus and Other Risk Factors in Cervical Cancer by ARNHEIM DAHLSTRÖM, Lisen, ANDERSSON, Kristin, JELLUM, Egil, KOSKELA, Pentti, WADELL, Göran, LEHTINEN, Matti, DILLNER, Joakim, LUOSTARINEN, Tapio, THORESEN, Steinar, ÖGMUNDSDOTTIR, Helga, TRYGGVADOTTIR, Laufey, WIKLUND, Fredrik, SKARE, Gry B, EKLUND, Carina, SJÖLIN, Kia

“…Several sexually transmitted infections (STI) have been reported to interact with human papillomavirus (HPV) in the etiology of cervical cancer. A large cohort…”
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Loss of lysosomal membrane protein NCU-G1 in mice results in spontaneous liver fibrosis with accumulation of lipofuscin and iron in Kupffer cells by Kong, Xiang Y, Nesset, Cecilie Kasi, Damme, Markus, Løberg, Else-Marit, Lübke, Torben, Mæhlen, Jan, Andersson, Kristin B, Lorenzo, Petra I, Roos, Norbert, Thoresen, G Hege, Rustan, Arild C, Kase, Eili T, Eskild, Winnie

“…Human kidney predominant protein, NCU-G1, is a highly conserved protein with an unknown biological function. Initially described as a nuclear protein, it was…”
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Cre-loxP DNA recombination is possible with only minimal unspecific transcriptional changes and without cardiomyopathy in Tg(alphaMHC-MerCreMer) mice by Hougen, Karina, Aronsen, Jan Magnus, Stokke, Mathis K, Enger, Ulla, Nygard, Stale, Andersson, Kristin B, Christensen, Geir, Sejersted, Ole M, Sjaastad, Ivar

“…Cre-loxP technology for conditional gene inactivation is a powerful tool in cardiovascular research. Induction of gene inactivation can be carried out by per…”
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Tamoxifen administration routes and dosage for inducible Cre-mediated gene disruption in mouse hearts by Andersson, Kristin B, Winer, Lisbeth H, Mørk, Halvor K, Molkentin, Jeffery D, Jaisser, Frédéric

“…Tissue-specific and time-dependent control of in vivo gene disruption may be achieved using conditional knockout strategies in transgenic mice. Fusion of…”
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Reduced SERCA2 abundance decreases the propensity for Ca2+ wave development in ventricular myocytes by Stokke, Mathis K., Hougen, Karina, Sjaastad, Ivar, Louch, William E., Briston, Sarah J., Enger, Ulla H., Andersson, Kristin B., Christensen, Geir, Eisner, David A., Sejersted, Ole M., Trafford, Andrew W.

“…Aims To describe the overall role of reduced sarcoplasmic reticulum Ca2+ ATPase (SERCA2) for Ca2+ wave development. Methods and results SERCA2 knockout…”
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Seroreactivity to Cutaneous Human Papillomaviruses among Patients with Nonmelanoma Skin Cancer or Benign Skin Lesions by ANDERSSON, Kristin, WATERBOER, Tim, KIRNBAUER, Reinhard, SLUPETZKY, Katharina, IFTNER, Thomas, DE VILLIERS, Ethel-Michele, FORSLUND, Ola, PAWLITA, Michael, DILLNER, Joakim

“…Cutaneous human papillomaviruses (HPV) are common in nonmelanoma skin cancers, benign skin lesions, and healthy skin. Increased seroprevalences for cutaneous…”
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Slowed relaxation and preserved maximal force in soleus muscles of mice with targeted disruption of the Serca2 gene in skeletal muscle by Sjåland, Cecilie, Lunde, Per Kristian, Swift, Fredrik, Munkvik, Morten, Ericsson, Madelene, Lunde, Marianne, Boye, Sigurd, Christensen, Geir, Ellingsen, Øyvind, Sejersted, Ole M., Andersson, Kristin B.

“…Non‐technical summary  Muscle function depends on tightly regulated Ca2+ movement between the intracellular sarcoplasmic reticulum (SR) Ca2+ store and…”
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Postoperative wound infections after a proctectomy-Patient experiences by Hassel, Karin, Andersson, Kristin, Koinberg, Inga-Lill, Wennström, Berith

“…Poor perineal wound healing and infections after proctectomy surgery cause a significant proportion of physical and psychological morbidities, such as pain,…”
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Extreme sarcoplasmic reticulum volume loss and compensatory T-tubule remodeling after Serca2 knockout by Swift, Fredrik, Franzini-Armstrong, Clara, Øyehaug, Leiv, Enger, Ulla Helene, Andersson, Kristin Brevik, Christensen, Geir, Sejersted, Ole M., Louch, William E.

“…Cardiomyocyte contraction and relaxation are controlled by Ca²⁺ handling, which can be regulated to meet demand. Indeed, major reduction in sarcoplasmic…”
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Separate mechanisms cause anemia in ischemic vs. nonischemic murine heart failure by Iversen, Per O, Andersson, Kristin B, Finsen, Alexandra V, Sjaastad, Ivar, von Lueder, Thomas G, Sejersted, Ole M, Attramadal, Havard, Christensen, Geir

“…In ischemic congestive heart failure (CHF), anemia is associated with poor prognosis. Whether anemia develops in nonischemic CHF is uncertain. The…”
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High-intensity exercise training in mice with cardiomyocyte-specific disruption of Serca2 by ERICSSON, Madelene, ANDERSSON, Kristin B, AMUNDSEN, Brage H, TORP, Sverre H, SJAASTAD, Ivar, CHRISTENSEN, Geir, SEJERSTED, Ole M, ELLINGSEN, Øyvind

“…Several lines of evidence indicate that the sarco(endo)plasmic reticulum ATPase type 2 (SERCA2) is essential for maintaining myocardial calcium handling and…”
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Exercise training before cardiac-specific Serca2 disruption attenuates the decline in cardiac function in mice by ERICSSON, Madelene, SJALAND, Cecilie, ANDERSSON, Kristin B, SJAASTAD, Ivar, CHRISTENSEN, Geir, SEJERSTED, Ole M, ELLINGSEN, Øyvind

“…In the heart, function of the sarco(endo)plasmic Ca(2+)-ATPase (SERCA2) is closely linked to contractility, cardiac function, and aerobic fitness. SERCA2…”
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Mice carrying a conditional Serca2(flox) allele for the generation of Ca(2+) handling-deficient mouse models by Andersson, Kristin B, Finsen, Alexandra V, Sjåland, Cecilie, Winer, Lisbeth H, Sjaastad, Ivar, Odegaard, Annlaug, Louch, William E, Wang, Yibin, Chen, Ju, Chien, Kenneth R, Sejersted, Ole M, Christensen, Geir

“…Sarco(endo)plasmic reticulum calcium ATPases (SERCA) are cellular pumps that transport Ca(2+) into the sarcoplasmic reticulum (SR). Serca2 is the most widely…”
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Repeat prescriptions: refill adherence in relation to patient and prescriber characteristics, reimbursement level and type of medication by Andersson, Kristin, Melander, Arne, Svensson, Carin, Lind, Owe, Nilsson, J. Lars G.

“…Background: Repeat prescribing used in long-term pharmacotherapy is often associated with inadequate patient medication, including non-adherence. In this paper…”
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Progressive slowing of calcium transient decline and development of diastolic heart failure in SERCA2 knockout mice by Louch, William E, Aronsen, Magnus, Sjaastad, Ivar, Mørk, Halvor K, Andersson, Kristin B, Hougen, Karina, Christensen, Geir, Sejersted, Ole M

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