Search Results - "ANDERSSON, K"
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PDE5 inhibitors – pharmacology and clinical applications 20 years after sildenafil discovery
Published in British journal of pharmacology (01-07-2018)“…The discovery of the nitric oxide/cGMP pathway was the basis for our understanding of many normal physiological functions and the pathophysiology of several…”
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Mechanisms of penile erection and basis for pharmacological treatment of erectile dysfunction
Published in Pharmacological reviews (01-12-2011)“…Erection is basically a spinal reflex that can be initiated by recruitment of penile afferents, both autonomic and somatic, and supraspinal influences from…”
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Purinergic signalling in the urinary bladder
Published in Autonomic neuroscience (01-09-2015)“…Abstract It is well established that in most species, exocytotic vesicular release of ATP from parasympathetic neurons contributes to contraction of the…”
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Effects of socialising piglets on sow and piglet performance and behaviour of entire male piglets
Published in Animal (Cambridge, England) (01-03-2024)“…•Mixing of alien pigs generally causes aggressive behaviour and decreased welfare.•Piglets from two litters can easily become ‘socialised’ by a small opening…”
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Comparative Study of Two Chitin-Active and Two Cellulose-Active AA10-Type Lytic Polysaccharide Monooxygenases
Published in Biochemistry (Easton) (18-03-2014)“…Lytic polysaccharide monooxygenases (LPMOs), found in family 9 (previously GH61), family 10 (previously CBM33), and the newly discovered family 11 of auxiliary…”
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LUTS treatment: Future treatment options
Published in Neurourology and urodynamics (01-10-2007)“…Lower urinary tract symptoms (LUTS) are commonly divided into storage, voiding, and postmicturition symptoms, and may occur in both men and women. Male LUTS…”
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Compliance possibilities for the future ECA regulations through the use of abatement technologies or change of fuels
Published in Transportation research. Part D, Transport and environment (01-05-2014)“…•Comparison of three options complying with ECA sulphur and NOX tier III regulation.•These options do not reduce the impact on climate change in the fuel life…”
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Diagnostic and therapeutic implications of new molecular biomarkers in salivary gland cancers
Published in Oral oncology (01-08-2014)“…Summary Salivary gland carcinomas (SGCs) are uncommon tumors, constituting approximately 5% of all cancers of the head and neck. They are a heterogeneous group…”
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Small-molecule-mediated OGG1 inhibition attenuates pulmonary inflammation and lung fibrosis in a murine lung fibrosis model
Published in Nature communications (06-02-2023)“…Interstitial lung diseases such as idiopathic pulmonary fibrosis (IPF) are caused by persistent micro-injuries to alveolar epithelial tissues accompanied by…”
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Urethral afferent signalling: role of 5‐HT paraneurons
Published in Acta Physiologica (01-02-2018)Get full text
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The impact of climate change on winter road maintenance and traffic accidents in West Midlands, UK
Published in Accident analysis and prevention (2011)“…▶ The length of the winter season will be reduced over the next 80 years. ▶ The number of accidents caused due to slipperiness will decrease by 43%. ▶…”
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Identification of ETV6-RUNX1-like and DUX4-rearranged subtypes in paediatric B-cell precursor acute lymphoblastic leukaemia
Published in Nature communications (06-06-2016)“…Fusion genes are potent driver mutations in cancer. In this study, we delineate the fusion gene landscape in a consecutive series of 195 paediatric B-cell…”
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The landscape of gene fusions and somatic mutations in salivary gland neoplasms – Implications for diagnosis and therapy
Published in Oral oncology (01-06-2016)“…Highlights • Salivary gland neoplasms show a specific gene fusion network. • The fusions are new diagnostic and prognostic biomarkers. • Subtypes of salivary…”
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Pharmacology of Penile Erection
Published in Pharmacological reviews (01-09-2001)“…Erection is basically a spinal reflex that can be initiated by recruitment of penile afferents, but also by visual, olfactory, and imaginary stimuli. The…”
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Targeting the Oncogenic Transcriptional Regulator MYB in Adenoid Cystic Carcinoma by Inhibition of IGF1R/AKT Signaling
Published in JNCI : Journal of the National Cancer Institute (01-09-2017)“…Adenoid cystic carcinoma (ACC) is an aggressive cancer with no curative treatment for patients with recurrent/metastatic disease. The MYB-NFIB gene fusion is…”
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The landscape of somatic mutations in infant MLL-rearranged acute lymphoblastic leukemias
Published in Nature genetics (01-04-2015)“…Anna Andersson, Tanja Gruber, James Downing and colleagues report a genomic analysis of infant acute lymphoblastic leukemias with MLL rearrangements. They…”
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Autonomic nervous control of the urinary bladder
Published in Acta Physiologica (01-01-2013)“…The autonomic nervous system plays an important role in the regulation of the urinary bladder function. Under physiological circumstances, noradrenaline,…”
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Phase II study on the efficacy and safety of the EP1 receptor antagonist ONO-8539 for nonneurogenic overactive bladder syndrome
Published in The Journal of urology (01-01-2014)“…We evaluated the efficacy, safety and tolerability of the EP1 receptor antagonist ONO-8539 in patients with overactive bladder syndrome. This was a 12-week,…”
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The genomic landscape of core-binding factor acute myeloid leukemias
Published in Nature genetics (01-12-2016)“…Lars Bullinger, Jinghui Zhang, Jeffery Klco, James Downing and colleagues report a detailed genomic analysis of pediatric and adult core-binding factor acute…”
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Antimuscarinics and the Overactive Detrusor—Which Is the Main Mechanism of Action?
Published in European Urology (2003)“…Contraction of the bladder, voluntary or involuntary, involves stimulation of the muscarinic receptors on the detrusor by acetylcholine, released from…”
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