Search Results - "ANDERSON, Michelle A"
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Daisy-chain gene drives: The role of low cut-rate, resistance mutations, and maternal deposition
Published in PLoS genetics (19-09-2022)“…The introgression of genetic traits through gene drive may serve as a powerful and widely applicable method of biological control. However, for many…”
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Closing the gap to effective gene drive in Aedes aegypti by exploiting germline regulatory elements
Published in Nature communications (20-01-2023)“…CRISPR/Cas9-based homing gene drives have emerged as a potential new approach to mosquito control. While attempts have been made to develop such systems in…”
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Considerations for homology-based DNA repair in mosquitoes: Impact of sequence heterology and donor template source
Published in PLoS genetics (18-02-2022)“…The increasing prevalence of insecticide resistance and the ongoing global burden of vector-borne diseases have encouraged new efforts in mosquito control. For…”
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A multiplexed, confinable CRISPR/Cas9 gene drive can propagate in caged Aedes aegypti populations
Published in Nature communications (25-01-2024)“…Aedes aegypti is the main vector of several major pathogens including dengue, Zika and chikungunya viruses. Classical mosquito control strategies utilizing…”
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5
A CRISPR endonuclease gene drive reveals distinct mechanisms of inheritance bias
Published in Nature communications (21-11-2022)“…CRISPR/Cas gene drives can bias transgene inheritance through different mechanisms. Homing drives are designed to replace a wild-type allele with a copy of a…”
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Quality of Life in Chronic Pancreatitis is Determined by Constant Pain, Disability/Unemployment, Current Smoking, and Associated Co-Morbidities
Published in The American journal of gastroenterology (01-04-2017)“…Chronic pancreatitis (CP) has a profound independent effect on quality of life (QOL). Our aim was to identify factors that impact the QOL in CP patients. We…”
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TALEN-based gene disruption in the dengue vector Aedes aegypti
Published in PloS one (21-03-2013)“…In addition to its role as the primary vector for dengue viruses, Aedes aegypti has a long history as a genetic model organism for other bloodfeeding…”
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AePUb promoter length modulates gene expression in Aedes aegypti
Published in Scientific reports (21-11-2023)“…Molecular tools for modulating transgene expression in Aedes aegypti are few. Here we demonstrate that adjustments to the AePUb promoter length can alter…”
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CRISPR/Cas-9 mediated knock-in by homology dependent repair in the West Nile Virus vector Culex quinquefasciatus Say
Published in Scientific reports (22-07-2021)“…Culex quinquefasciatus Say is a mosquito distributed in both tropical and subtropical regions of the world. It is a night-active, opportunistic blood-feeder…”
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Management of ingested foreign bodies and food impactions
Published in Gastrointestinal endoscopy (01-06-2011)Get full text
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A male-determining factor in the mosquito Aedes aegypti
Published in Science (American Association for the Advancement of Science) (12-06-2015)“…Sex determination in the mosquito Aedes aegypti is governed by a dominant male-determining factor (M factor) located within a Y chromosome–like region called…”
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Glycoprotein Biomarker Panel for Pancreatic Cancer Discovered by Quantitative Proteomics Analysis
Published in Journal of proteome research (04-04-2014)“…Pancreatic cancer is a lethal disease where specific early detection biomarkers would be very valuable to improve outcomes in patients. Many previous studies…”
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The role of endoscopy in the evaluation of suspected choledocholithiasis
Published in Gastrointestinal endoscopy (2010)Get full text
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Mechanisms of CFTR functional variants that impair regulated bicarbonate permeation and increase risk for pancreatitis but not for cystic fibrosis
Published in PLoS genetics (01-07-2014)“…CFTR is a dynamically regulated anion channel. Intracellular WNK1-SPAK activation causes CFTR to change permeability and conductance characteristics from a…”
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Complications of ERCP
Published in Gastrointestinal endoscopy (01-03-2012)Get full text
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Deep sequencing of pyrethroid-resistant bed bugs reveals multiple mechanisms of resistance within a single population
Published in PloS one (19-10-2011)“…A frightening resurgence of bed bug infestations has occurred over the last 10 years in the U.S. and current chemical methods have been inadequate for…”
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Chronic Pancreatitis Pain Pattern and Severity Are Independent of Abdominal Imaging Findings
Published in Clinical gastroenterology and hepatology (01-03-2015)“…Background & Aims Chronic pancreatitis is characterized by inflammation, atrophy, fibrosis with progressive ductal changes, and functional changes that include…”
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Detection, evaluation and treatment of diabetes mellitus in chronic pancreatitis: Recommendations from PancreasFest 2012
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01-07-2013)“…Abstract Description Diabetes and glucose intolerance are common complications of chronic pancreatitis, yet clinical guidance on their detection,…”
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Management of antithrombotic agents for endoscopic procedures
Published in Gastrointestinal endoscopy (01-12-2009)Get full text
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Large-Scale Identification of Core-Fucosylated Glycopeptide Sites in Pancreatic Cancer Serum Using Mass Spectrometry
Published in Journal of proteome research (03-04-2015)“…Glycosylation has significant effects on protein function and cell metastasis, which are important in cancer progression. It is of great interest to identify…”
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