Search Results - "ANDERSON, Michelle A"

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    Daisy-chain gene drives: The role of low cut-rate, resistance mutations, and maternal deposition by Verkuijl, Sebald A N, Anderson, Michelle A E, Alphey, Luke, Bonsall, Michael B

    Published in PLoS genetics (19-09-2022)
    “…The introgression of genetic traits through gene drive may serve as a powerful and widely applicable method of biological control. However, for many…”
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    Closing the gap to effective gene drive in Aedes aegypti by exploiting germline regulatory elements by Anderson, Michelle A. E., Gonzalez, Estela, Ang, Joshua X. D., Shackleford, Lewis, Nevard, Katherine, Verkuijl, Sebald A. N., Edgington, Matthew P., Harvey-Samuel, Tim, Alphey, Luke

    Published in Nature communications (20-01-2023)
    “…CRISPR/Cas9-based homing gene drives have emerged as a potential new approach to mosquito control. While attempts have been made to develop such systems in…”
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    Considerations for homology-based DNA repair in mosquitoes: Impact of sequence heterology and donor template source by Ang, Joshua Xin De, Nevard, Katherine, Ireland, Rebekah, Purusothaman, Deepak-Kumar, Verkuijl, Sebald A N, Shackleford, Lewis, Gonzalez, Estela, Anderson, Michelle A E, Alphey, Luke

    Published in PLoS genetics (18-02-2022)
    “…The increasing prevalence of insecticide resistance and the ongoing global burden of vector-borne diseases have encouraged new efforts in mosquito control. For…”
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    A CRISPR endonuclease gene drive reveals distinct mechanisms of inheritance bias by Verkuijl, Sebald A. N., Gonzalez, Estela, Li, Ming, Ang, Joshua X. D., Kandul, Nikolay P., Anderson, Michelle A. E., Akbari, Omar S., Bonsall, Michael B., Alphey, Luke

    Published in Nature communications (21-11-2022)
    “…CRISPR/Cas gene drives can bias transgene inheritance through different mechanisms. Homing drives are designed to replace a wild-type allele with a copy of a…”
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    TALEN-based gene disruption in the dengue vector Aedes aegypti by Aryan, Azadeh, Anderson, Michelle A E, Myles, Kevin M, Adelman, Zach N

    Published in PloS one (21-03-2013)
    “…In addition to its role as the primary vector for dengue viruses, Aedes aegypti has a long history as a genetic model organism for other bloodfeeding…”
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    AePUb promoter length modulates gene expression in Aedes aegypti by Anderson, Michelle A. E., Leftwich, Philip T., Wilson, Ray, Paladino, Leonela Z. Carabajal, Basu, Sanjay, Rooney, Sara, Adelman, Zach N., Alphey, Luke

    Published in Scientific reports (21-11-2023)
    “…Molecular tools for modulating transgene expression in Aedes aegypti are few. Here we demonstrate that adjustments to the AePUb promoter length can alter…”
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    CRISPR/Cas-9 mediated knock-in by homology dependent repair in the West Nile Virus vector Culex quinquefasciatus Say by Purusothaman, Deepak-Kumar, Shackleford, Lewis, Anderson, Michelle A. E., Harvey-Samuel, Tim, Alphey, Luke

    Published in Scientific reports (22-07-2021)
    “…Culex quinquefasciatus Say is a mosquito distributed in both tropical and subtropical regions of the world. It is a night-active, opportunistic blood-feeder…”
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    A male-determining factor in the mosquito Aedes aegypti by Hall, Andrew Brantley, Basu, Sanjay, Jiang, Xiaofang, Qi, Yumin, Timoshevskiy, Vladimir A., Biedler, James K., Sharakhova, Maria V., Elahi, Rubayet, Anderson, Michelle A. E., Chen, Xiao-Guang, Sharakhov, Igor V., Adelman, Zach N., Tu, Zhijian

    “…Sex determination in the mosquito Aedes aegypti is governed by a dominant male-determining factor (M factor) located within a Y chromosome–like region called…”
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    Glycoprotein Biomarker Panel for Pancreatic Cancer Discovered by Quantitative Proteomics Analysis by Nie, Song, Lo, Andy, Wu, Jing, Zhu, Jianhui, Tan, Zhijing, Simeone, Diane M, Anderson, Michelle A, Shedden, Kerby A, Ruffin, Mack T, Lubman, David M

    Published in Journal of proteome research (04-04-2014)
    “…Pancreatic cancer is a lethal disease where specific early detection biomarkers would be very valuable to improve outcomes in patients. Many previous studies…”
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    Deep sequencing of pyrethroid-resistant bed bugs reveals multiple mechanisms of resistance within a single population by Adelman, Zach N, Kilcullen, Kathleen A, Koganemaru, Reina, Anderson, Michelle A E, Anderson, Troy D, Miller, Dini M

    Published in PloS one (19-10-2011)
    “…A frightening resurgence of bed bug infestations has occurred over the last 10 years in the U.S. and current chemical methods have been inadequate for…”
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    Large-Scale Identification of Core-Fucosylated Glycopeptide Sites in Pancreatic Cancer Serum Using Mass Spectrometry by Tan, Zhijing, Yin, Haidi, Nie, Song, Lin, Zhenxin, Zhu, Jianhui, Ruffin, Mack T, Anderson, Michelle A, Simeone, Diane M, Lubman, David M

    Published in Journal of proteome research (03-04-2015)
    “…Glycosylation has significant effects on protein function and cell metastasis, which are important in cancer progression. It is of great interest to identify…”
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