Search Results - "ANDERSEN, Thomas L"

Transcriptional Dynamics of Hepatic Sinusoid‐Associated Cells After Liver Injury by Terkelsen, Mike K., Bendixen, Sofie M., Hansen, Daniel, Scott, Emma A.H., Moeller, Andreas F., Nielsen, Ronni, Mandrup, Susanne, Schlosser, Anders, Andersen, Thomas L., Sorensen, Grith L., Krag, Aleksander, Natarajan, Kedar N., Detlefsen, Sönke, Dimke, Henrik, Ravnskjaer, Kim

“…Background and Aims Hepatic sinusoidal cells are known actors in the fibrogenic response to injury. Activated hepatic stellate cells (HSCs), liver sinusoidal…”
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Efficient 11C‑Carbonylation of Isolated Aryl Palladium Complexes for PET: Application to Challenging Radiopharmaceutical Synthesis by Andersen, Thomas L, Friis, Stig D, Audrain, Hélène, Nordeman, Patrik, Antoni, Gunnar, Skrydstrup, Troels

“…We describe the successful implementation of palladium-aryl oxidative addition complexes as stoichiometric reagents in carbonylation reactions with 11CO to…”
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Myeloma-Modified Adipocytes Exhibit Metabolic Dysfunction and a Senescence-Associated Secretory Phenotype by Fairfield, Heather, Dudakovic, Amel, Khatib, Casper M, Farrell, Mariah, Costa, Samantha, Falank, Carolyne, Hinge, Maja, Murphy, Connor S, DeMambro, Victoria, Pettitt, Jessica A, Lary, Christine W, Driscoll, Heather E, McDonald, Michelle M, Kassem, Moustapha, Rosen, Clifford, Andersen, Thomas L, van Wijnen, Andre J, Jafari, Abbas, Reagan, Michaela R

“…Bone marrow adipocytes (BMAd) have recently been implicated in accelerating bone metastatic cancers, such as acute myelogenous leukemia and breast cancer…”
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Evidence for Single-Electron Pathways in the Reaction between Palladium(II) Dialkyl Complexes and Alkyl Bromides under Thermal and Photoinduced Conditions by Andersen, Thomas L, Kramer, Søren, Overgaard, Jacob, Skrydstrup, Troels

“…Palladium­(II) dialkyl complexes have previously been studied for their formation of alkanes through reductive elimination. More recently, these complexes,…”
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Adipocyte-induced transdifferentiation of osteoblasts and its potential role in age-related bone loss by Clabaut, Aline, Grare, Céline, Rolland-Valognes, Gaëlle, Letarouilly, Jean-Guillaume, Bourrier, Chantal, Andersen, Thomas L, Sikjær, Tanja, Rejnmark, Lars, Ejersted, Charlotte, Pastoureau, Philippe, Hardouin, Pierre, Sabatini, Massimo, Broux, Odile

“…Our preliminary findings have lead us to propose bone marrow adipocyte secretions as new contributors to bone loss. Indeed, using a coculture model based on…”
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A reversal phase arrest uncoupling the bone formation and resorption contributes to the bone loss in glucocorticoid treated ovariectomised aged sheep by Andreasen, Christina M, Ding, Ming, Overgaard, Søren, Bollen, Peter, Andersen, Thomas L

“…Abstract Large animals as sheep are often used as models for human osteoporosis. Our aim was therefore to determine how glucocorticoid treatment of…”
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Legumain Regulates Differentiation Fate of Human Bone Marrow Stromal Cells and Is Altered in Postmenopausal Osteoporosis by Jafari, Abbas, Qanie, Diyako, Andersen, Thomas L., Zhang, Yuxi, Chen, Li, Postert, Benno, Parsons, Stuart, Ditzel, Nicholas, Khosla, Sundeep, Johansen, Harald Thidemann, Kjærsgaard-Andersen, Per, Delaisse, Jean-Marie, Abdallah, Basem M., Hesselson, Daniel, Solberg, Rigmor, Kassem, Moustapha

“…Secreted factors are a key component of stem cell niche and their dysregulation compromises stem cell function. Legumain is a secreted cysteine protease…”
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Disturbed bone marrow adiposity in patients with Cushing's syndrome and glucocorticoid- and postmenopausal- induced osteoporosis by Sørensen, Nina N, Andreasen, Christina M, Jensen, Pia R, Hauge, Ellen M, Bollerslev, Jens, Delaissé, Jean-Marie, Kassem, Moustapha, Jafari, Abbas, Diaz-delCastillo, Marta, Andersen, Thomas L

“…Skeletal stem/progenitor cells (SSPCs) in the bone marrow can differentiate into osteoblasts or adipocytes in response to microenvironmental signalling input,…”
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General Method for the Preparation of Active Esters by Palladium-Catalyzed Alkoxycarbonylation of Aryl Bromides by de Almeida, Angelina M, Andersen, Thomas L, Lindhardt, Anders T, de Almeida, Mauro V, Skrydstrup, Troels

“…A useful method was developed for the synthesis of active esters by palladium-catalyzed alkoxycarbonylation of (hetero)aromatic bromides. The protocol was…”
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Correlation between Absence of Bone Remodeling Compartment Canopies, Reversal Phase Arrest, and Deficient Bone Formation in Post-Menopausal Osteoporosis by Andersen, Thomas L, Hauge, Ellen M, Rolighed, Lars, Bollerslev, Jens, Kjærsgaard-Andersen, Per, Delaisse, Jean-Marie

“…Bone remodeling compartments (BRCs) were recently recognized to be present in patients with primary hyperparathyroidism and critical for bone reconstruction in…”
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Drinking and Water Handling in the Medaka Intestine: A Possible Role of Claudin-15 in Paracellular Absorption? by Tipsmark, Christian K, Nielsen, Andreas M, Bossus, Maryline C, Ellis, Laura V, Baun, Christina, Andersen, Thomas L, Dreier, Jes, Brewer, Jonathan R, Madsen, Steffen S

“…When euryhaline fish move between fresh water (FW) and seawater (SW), the intestine undergoes functional changes to handle imbibed SW. In Japanese medaka, the…”
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Absence of an osteopetrosis phenotype in IKBKG (NEMO) mutation-positive women: A case-control study by Frost, Morten, Tencerova, Michaela, Andreasen, Christina M., Andersen, Thomas L., Ejersted, Charlotte, Svaneby, Dea, Qui, Weimin, Kassem, Moustapha, Zarei, Allahdad, McAlister, William H., Veis, Deborah J., Whyte, Michael P., Frederiksen, Anja L.

“…NF-κB essential modulator (NEMO), encoded by IKBKG, is necessary for activation of the ubiquitous transcription factor nuclear factor…”
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Resveratrol inhibits myeloma cell growth, prevents osteoclast formation, and promotes osteoblast differentiation by BOISSY, Patrice, ANDERSEN, Thomas L, ABDALLAH, Basem M, KASSEM, Moustapha, PLESNER, Torben, DELAISSE, Jean-Marie

“…Multiple myeloma is characterized by the accumulation of clonal malignant plasma cells in the bone marrow, which stimulates bone destruction by osteoclasts and…”
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Spatial Organization of Osteoclastic Coupling Factors and Their Receptors at Human Bone Remodeling Sites by Borggaard, Xenia G., Nielsen, Malene H., Delaisse, Jean-Marie, Andreasen, Christina M., Andersen, Thomas L.

“…The strictly regulated bone remodeling process ensures that osteoblastic bone formation is coupled to osteoclastic bone resorption. This coupling is regulated…”
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Bone Canopies in Pediatric Renal Osteodystrophy by Pereira, Renata C, Andersen, Thomas L, Friedman, Peter A, Tumber, Navdeep, Salusky, Isidro B, Wesseling-Perry, Katherine

“…Pediatric renal osteodystrophy (ROD) is characterized by changes in bone turnover, mineralization, and volume that are brought about by alterations in bone…”
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Mapping RANKL- and OPG-expressing cells in bone tissue: the bone surface cells as activators of osteoclastogenesis and promoters of the denosumab rebound effect by El-Masri, Bilal M, Andreasen, Christina M, Laursen, Kaja S, Kofod, Viktoria B, Dahl, Xenia G, Nielsen, Malene H, Thomsen, Jesper S, Brüel, Annemarie, Sørensen, Mads S, Hansen, Lars J, Kim, Albert S, Taylor, Victoria E, Massarotti, Caitlyn, McDonald, Michelle M, You, Xiaomeng, Charles, Julia F, Delaisse, Jean-Marie, Andersen, Thomas L

“…Denosumab is a monoclonal anti-RANKL antibody that inhibits bone resorption, increases bone mass, and reduces fracture risk. Denosumab discontinuation causes…”
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Rapid and Efficient Conversion of 11CO2 to 11CO through Silacarboxylic Acids: Applications in Pd-Mediated Carbonylations by Nordeman, Patrik, Friis, Stig D., Andersen, Thomas L., Audrain, Hélène, Larhed, Mats, Skrydstrup, Troels, Antoni, Gunnar

“…Herein, we present a new rapid, efficient, and low‐cost radiosynthetic protocol for the conversion of 11CO2 to 11CO and its subsequent application in…”
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Synthesis and Evaluation of Silanediols as Highly Selective Uncompetitive Inhibitors of Human Neutrophil Elastase by Madsen, Julie L. H, Andersen, Thomas L, Santamaria, Salvatore, Nagase, Hideaki, Enghild, Jan J, Skrydstrup, Troels

“…Chronic obstructive pulmonary disease (COPD) is an increasing health problem and is estimated to be the fifth leading cause of death in 2020 according to the…”
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Matrix metalloproteinases (MMP) and cathepsin K contribute differently to osteoclastic activities by Delaissé, Jean-Marie, Andersen, Thomas L., Engsig, Michael T., Henriksen, Kim, Troen, Tine, Blavier, Laurence

“…The best established proteolytic event of osteoclasts is bone matrix solubilization by the cysteine proteinase cathepsin K. Here, however, we draw the…”
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Correction: Bone Canopies in Pediatric Renal Osteodystrophy by Pereira, Renata C, Andersen, Thomas L, Friedman, Peter A, Tumber, Navdeep, Salusky, Isidro B, Wesseling-Perry, Katherine

“…[This corrects the article DOI: 10.1371/journal.pone.0152871.]…”
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