Search Results - "ANDERA, L"

The role of apoptosis in cancer development and treatment: focusing on the development and treatment of hematologic malignancies by Zivny, J, Klener, Jr, P, Pytlik, R, Andera, L

“…Apoptosis is a normal aspect of human physiology ensuring tissue homeostasis. Evasion of endogenous cell death processes, including apoptosis, represents one…”
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Newly established tumourigenic primary human colon cancer cell lines are sensitive to TRAIL-induced apoptosis in vitro and in vivo by OIKONOMOU, E, KOTHONIDIS, K, ZOGRAFOS, G, NASIOULAS, G, ANDERA, L, PINTZAS, A

“…Most data on the therapeutic potential of tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) as well as resistance to FAS ligand (FASL) in…”
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902 BRAFV600E Inhibitor Resistance Mechanisms – Co-treatment With TRAIL and PI3K Inhibitors can Sensitise to Apoptosis Resistant Colon Cancer Cells by Pintzas, A, Oikonomou, E, Joyce, T, Kosmidou, V, Koc, M, Sourkova, V, Andera, L

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Upregulation of c-FLIP-short in response to TRAIL promotes survival of NSCLC cells, which could be suppressed by inhibition of Ca2+/calmodulin signaling by Kaminskyy, V O, Surova, O V, Piskunova, T, Zborovskaya, I B, Tchevkina, E M, Andera, L, Zhivotovsky, B

“…TNF-related apoptosis-inducing ligand (TRAIL) is a promising cytokine for killing tumor cells. However, a number of studies have demonstrated that different…”
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TRAIL (Apo2l) suppresses growth of primary human leukemia and myelodysplasia progenitors by PLASILOVA, M, ZIVNY, J, JELINEK, J, NEUWIRTOVA, R, CERMAK, J, NECAS, E, ANDERA, L, STOPKA, T

“…Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL, APO2L) has been shown to induce apoptosis in a number of tumor cell lines as well as in some…”
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α-Tocopheryl succinate and TRAIL selectively synergise in induction of apoptosis in human malignant mesothelioma cells by TOMASETTI, M, RIPPO, M. R, ALLEVA, R, MORETTI, S, ANDERA, L, NEUZIL, J, PROCOPIO, A

“…Malignant mesothelioma (MM) is a fatal type of neoplasia with poor therapeutic prognosis, largely due to resistance to apoptosis. We investigated the apoptotic…”
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Multi-level disruption of the extrinsic apoptotic pathway mediates resistance of leukemia cells to TNF-related apoptosis-inducing ligand (TRAIL) by Leahomschi, S, Molinsky, J, Klanova, M, Andera, L, Peterka, M, Gasova, Z, Klener, Sr, P, Trneny, M, Necas, E, Simonova, T, Zivny, J, Klener, Jr, P

“…Disruption of apoptotic pathways belongs to commonly reported molecular mechanisms that underlie cancer drug resistance. Tumor necrosis factor (TNF)-related…”
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Coenzyme Q blocks biochemical but not receptor‐mediated apoptosis by increasing mitochondrial antioxidant protection by Alleva, Renata, Tomasetti, Marco, Andera, Ladislav, Gellert, Nina, Borghi, Battista, Weber, Christian, Murphy, Michael P., Neuzil, Jiri

“…Generation of free radicals is often associated with the induction and progression of apoptosis. Therefore, antioxidants can prove anti‐apoptotic, and can help…”
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Vitamin E analogs: a new class of multiple action agents with anti-neoplastic and anti-atherogenic activity by Neuzil, J, Kågedal, K, Andera, L, Weber, C, Brunk, U T

“…The incidence of cancer and atherosclerosis, two most common causes of death in developed countries, has been stagnating or, even, increasing. Drugs effective…”
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Newly established tumourigenic primary human colon cancer cell lines are sensitive to TRAIL induced apoptosis in vitro and in vivo by Oikonomou, E, Kothonidis, K, Taoufik, E, Probert, E, Zografos, G, Nasioulas, G, Andera, L, Pintzas, A

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Functional interactions between p53 and the TFIIH complex are affected by tumour‐associated mutations by Léveillard, T., Andera, L., Bissonnette, N., Schaeffer, L., Bracco, L., Egly, J. M., Wasylyk, B.

“…The p53 tumour suppressor is mutated in the majority of human tumours. p53′s proposed role as the guardian of the genome is reflected in its multiple effects…”
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Transcription abnormalities potentiate apoptosis of normal human fibroblasts by Andera, L, Wasylyk, B

“…Apoptosis is a natural process by which damaged and potentially tumorigenic cells are removed. Induction of apoptosis is important in chemotherapy aimed at…”
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242 RAS and BRAF oncogenes sensitise colorectal tumours to TRAIL induced apoptosis: from cell and animal models to the clinic by Pintzas, A, Oikonomou, E, Andera, L, Zografos, G, Kontogeorgos, G, Kosmidou, V

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Enzymatically modified low-density lipoprotein upregulates CD36 in low-differentiated monocytic cells in a peroxisome proliferator-activated receptor-γ-dependent way by Jostarndt, K, Rubic, T, Kuhn, H, Anthosen, M.W, Andera, L, Gellert, N, Trottman, M, Weber, Christian, Johansen, B, Hrboticky, N, Neuzil, J

“…Peroxisome proliferator-activated receptor-γ (PPARγ) has been suggested to upregulate CD36. Since free oxidized polyunsaturated fatty acids are PPARγ ligands,…”
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6126 Presence of K-RAS and BRAF oncogenic mutations sensitise colorectal tumours to TRAIL induced apoptosis: evidence from cell and animal models translated to the clinic by Pintzas, A, Oikonomou, E, Andera, L, Zografos, G, Kontogeorgos, G, Kosmidou, V

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Determinants of affinity and mode of DNA binding at the carboxy terminus of the bacteriophage SPO1-encoded type II DNA-binding protein, TF1 by ANDERA, L, GEIDUSCHEK, E. P

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Tumour-initiating cells vs. cancer ‘stem’ cells and CD133: What’s in the name? by Neuzil, Jiri, Stantic, Marina, Zobalova, Renata, Chladova, Jaromira, Wang, Xiufang, Prochazka, Lubomir, Dong, Lanfeng, Andera, Ladislav, Ralph, Stephen J.

“…Recent evidence suggests that a subset of cells within a tumour have ‘stem-like’ characteristics. These tumour-initiating cells, distinct from non-malignant…”
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Induction, regulation and roles of neural adhesion molecule L1CAM in cellular senescence by Mrazkova, Blanka, Dzijak, Rastislav, Imrichova, Terezie, Kyjacova, Lenka, Barath, Peter, Dzubak, Petr, Holub, Dusan, Hajduch, Marian, Nahacka, Zuzana, Andera, Ladislav, Holicek, Petr, Vasicova, Pavla, Sapega, Olena, Bartek, Jiri, Hodny, Zdenek

“…Aging involves tissue accumulation of senescent cells (SC) whose elimination through senolytic approaches may evoke organismal rejuvenation. SC also contribute…”
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Cisplatin and a potent platinum(IV) complex-mediated enhancement of TRAIL-induced cancer cells killing is associated with modulation of upstream events in the extrinsic apoptotic pathway by VONDALOVA BLANAROVA, Olga, JELINKOVA, Iva, HOFMANOVA, Jiřina, VEREB, György, KOZUBIK, Alois, SZÖÖR, Arpád, SKENDER, Belma, SOUCEK, Karel, HORVATH, Viktor, VACULOVA, Alena, ANDERA, Ladislav, SOVA, Petr, SZÖLLÖSI, János

“…TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) can selectively trigger apoptosis in various cancer cell types. However, many cancer cells are…”
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Cell death signalling pathways in the pathogenesis and therapy of haematologic malignancies: overview of apoptotic pathways by Klener, Jr, P, Andera, L, Klener, P, Necas, E, Zivný, J

“…Apoptosis, a Greek descriptive term for falling leaves or petals, plays an important role in the progression of many diseases. Apoptosis is essential for the…”
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