Search Results - "ANANIEV, E"

The antimicrobial potential of Streptomyces from insect microbiomes by Chevrette, Marc G., Carlson, Caitlin M., Ortega, Humberto E., Thomas, Chris, Ananiev, Gene E., Barns, Kenneth J., Book, Adam J., Cagnazzo, Julian, Carlos, Camila, Flanigan, Will, Grubbs, Kirk J., Horn, Heidi A., Hoffmann, F. Michael, Klassen, Jonathan L., Knack, Jennifer J., Lewin, Gina R., McDonald, Bradon R., Muller, Laura, Melo, Weilan G. P., Pinto-Tomás, Adrián A., Schmitz, Amber, Wendt-Pienkowski, Evelyn, Wildman, Scott, Zhao, Miao, Zhang, Fan, Bugni, Tim S., Andes, David R., Pupo, Monica T., Currie, Cameron R.

“…Antimicrobial resistance is a global health crisis and few novel antimicrobials have been discovered in recent decades. Natural products, particularly from…”
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Discovery and Mechanism of Small Molecule Inhibitors Selective for the Chromatin-Binding Domains of Oncogenic UHRF1 by Liu, Wallace H, Miner, 3rd, Robert E, Albaugh, Brittany N, Ananiev, Gene E, Wildman, Scott A, Denu, John M

“…Chromatin abnormalities are common hallmarks of cancer cells, which exhibit alterations in DNA methylation profiles that can silence tumor suppressor genes…”
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Establishment of Reporter Lines for Detecting Fragile X Mental Retardation (FMR1) Gene Reactivation in Human Neural Cells by Li, Meng, Zhao, Huashan, Ananiev, Gene E., Musser, Michael T., Ness, Kathryn H., Maglaque, Dianne L., Saha, Krishanu, Bhattacharyya, Anita, Zhao, Xinyu

“…Human patient‐derived induced pluripotent stem cells (hiPSCs) provide unique opportunities for disease modeling and drug development. However, adapting hiPSCs…”
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Versatile synthetic alternatives to Matrigel for vascular toxicity screening and stem cell expansion by Nguyen, Eric H., Daly, William T., Le, Ngoc Nhi T., Farnoodian, Mitra, Belair, David G., Schwartz, Michael P., Lebakken, Connie S., Ananiev, Gene E., Saghiri, Mohammad Ali, Knudsen, Thomas B., Sheibani, Nader, Murphy, William L.

“…The physiological relevance of Matrigel as a cell-culture substrate and in angiogenesis assays is often called into question. Here, we describe an array-based…”
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Bacillimidazoles A-F, Imidazolium-Containing Compounds Isolated from a Marine Bacillus by Yan, Jia-Xuan, Wu, Qihao, Helfrich, Eric J N, Chevrette, Marc G, Braun, Doug R, Heyman, Heino, Ananiev, Gene E, Rajski, Scott R, Currie, Cameron R, Clardy, Jon, Bugni, Tim S

“…Chemical investigations of a marine sponge-associated revealed six new imidazolium-containing compounds, bacillimidazoles A-F ( - ). Previous reports of…”
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Predicting kinase inhibitors using bioactivity matrix derived informer sets by Zhang, Huikun, Ericksen, Spencer S, Lee, Ching-Pei, Ananiev, Gene E, Wlodarchak, Nathan, Yu, Peng, Mitchell, Julie C, Gitter, Anthony, Wright, Stephen J, Hoffmann, F Michael, Wildman, Scott A, Newton, Michael A

“…Prediction of compounds that are active against a desired biological target is a common step in drug discovery efforts. Virtual screening methods seek some…”
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Chromosome-Specific Molecular Organization of Maize (Zea mays L.) Centromeric Regions by Ananiev, E. V., Phillips, R. L., Rines, H. W.

“…A set of oat-maize chromosome addition lines with individual maize (Zea mays L.) chromosomes present in plants with a complete oat (Avena sativa L.) chromosome…”
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High Throughput Small Molecule Screen for Reactivation of FMR1 in Fragile X Syndrome Human Neural Cells by Hunt, Jack F V, Li, Meng, Risgaard, Ryan, Ananiev, Gene E, Wildman, Scott, Zhang, Fan, Bugni, Tim S, Zhao, Xinyu, Bhattacharyya, Anita

“…Fragile X syndrome (FXS) is the most common inherited cause of autism and intellectual disability. The majority of FXS cases are caused by transcriptional…”
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High-throughput screening identifies idarubicin as a preferential inhibitor of smooth muscle versus endothelial cell proliferation by Goel, Shakti A, Guo, Lian-Wang, Wang, Bowen, Guo, Song, Roenneburg, Drew, Ananiev, Gene E, Hoffmann, F Michael, Kent, K Craig

“…Intimal hyperplasia is the cause of the recurrent occlusive vascular disease (restenosis). Drugs currently used to treat restenosis effectively inhibit smooth…”
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Production and Characterization of Maize Chromosome 9 Radiation Hybrids Derived From an Oat-Maize Addition Line by Riera-Lizarazu, O, Vales, M. I, Ananiev, E. V, Rines, H. W, Phillips, R. L

“…In maize (Zea mays L., 2n = 2x = 20), map-based cloning and genome organization studies are often complicated because of the complexity of the genome. Maize…”
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Organ-specific effects of dark treatment on photosynthesis and the expression of photosynthesis-related genes by Mishev, K, Ananiev, E. D, Humbeck, K

“…The effects of two-day dark treatment, applied to whole plants or to individual organs, on the photosynthetic apparatus in cotyledons and first rosette leaves…”
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Complex Structure of Knob DNA on Maize Chromosome 9: Retrotransposon Invasion into Heterochromatin by Ananiev, E. V, Phillips, R. L, Rines, H. W

“…The recovery of maize (Zea mays L.) chromosome addition lines of oat (Avena sativa L.) from oat x maize crosses enables us to analyze the structure and…”
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A marine microbiome antifungal targets urgent-threat drug-resistant fungi by Zhang, Fan, Zhao, Miao, Braun, Doug R, Ericksen, Spencer S, Piotrowski, Jeff S, Nelson, Justin, Peng, Jian, Ananiev, Gene E, Chanana, Shaurya, Barns, Kenneth, Fossen, Jen, Sanchez, Hiram, Chevrette, Marc G, Guzei, Ilia A, Zhao, Changgui, Guo, Le, Tang, Weiping, Currie, Cameron R, Rajski, Scott R, Audhya, Anjon, Andes, David R, Bugni, Tim S

“…New antifungal drugs are urgently needed to address the emergence and transcontinental spread of fungal infectious diseases, such as pandrug-resistant…”
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A knob-associated tandem repeat in maize capable of forming fold-back DNA segments: are chromosome knobs megatransposons by Ananiev, E.V. (University of Minnesota, St. Paul, MN.), Phillips, R.L, Rines, H.W

“…A class of tandemly repeated DNA sequences (TR-1) of 350-bp unit length was isolated from the knob DNA of chromosome 9 of Zea mays L. Comparative fluorescence…”
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Mutant astrocytes differentiated from Rett syndrome patients-specific iPSCs have adverse effects on wild-type neurons by Williams, Emily Cunningham, Zhong, Xiaofen, Mohamed, Ahmed, Li, Ronghui, Liu, Yan, Dong, Qiping, Ananiev, Gene E., Mok, Jonathan Chern Choong, Lin, Benjamin Ray, Lu, Jianfeng, Chiao, Cassandra, Cherney, Rachel, Li, Hongda, Zhang, Su-Chun, Chang, Qiang

“…The disease mechanism of Rett syndrome (RTT) is not well understood. Studies in RTT mouse models have suggested a non-cell-autonomous role for astrocytes in…”
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Practical Model Selection for Prospective Virtual Screening by Liu, Shengchao, Alnammi, Moayad, Ericksen, Spencer S, Voter, Andrew F, Ananiev, Gene E, Keck, James L, Hoffmann, F. Michael, Wildman, Scott A, Gitter, Anthony

“…Virtual (computational) high-throughput screening provides a strategy for prioritizing compounds for experimental screens, but the choice of virtual screening…”
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A molecular, isozyme and morphological map of the barley (Hordeum vulgare) genome by KLEINHOFS, A, KILIAN, A, ANANIEV, E, DAHLEEN, L, KUDRNA, D, BOLLINGER, J, KNAPP, S. J, LIU, B, SORRELLS, M, HEUN, M, FRANCKOWIAK, J. D, HOFFMAN, D, MAROOF, M. A. S, SKADSEN, R, STEFFENSON, B. J, BIYASHEV, R. M, HAYES, P, CHEN, F. Q, LAPITAN, N, FENWICK, A, BLAKE, T. K, KANAZIN, V

“…A map of the barley genome consisting of 295 loci was constructed. These loci include 152 cDNA restriction fragment length polymorphism (RFLP), 114 genomic DNA…”
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Optical mapping discerns genome wide DNA methylation profiles by Ananiev, Gene E, Goldstein, Steve, Runnheim, Rod, Forrest, Dan K, Zhou, Shiguo, Potamousis, Konstantinos, Churas, Chris P, Bergendahl, Veit, Thomson, James A, Schwartz, David C

“…Methylation of CpG dinucleotides is a fundamental mechanism of epigenetic regulation in eukaryotic genomes. Development of methods for rapid genome wide…”
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A Complete Set of Maize Individual Chromosome Additions to the Oat Genome by Kynast, Ralf G., Riera-Lizarazu, Oscar, M. Isabel Vales, Okagaki, Ron J., Silvia B. Maquieira, Chen, Gang, Ananiev, Evgueni V., Wade E. Odland, Russell, Charles D., Stec, Adrian O., Suzanne M. Livingston, Herika A. Zaia, Rines, Howard W., Phillips, Ronald L.

“…All 10 chromosomes of maize (Zea mays, 2n = 2x = 20) were recovered as single additions to the haploid complement of oat (Avena sativa, 2n = 6x = 42) among F1…”
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Evaluating Scalable Supervised Learning for Synthesize-on-Demand Chemical Libraries by Alnammi, Moayad, Liu, Shengchao, Ericksen, Spencer S., Ananiev, Gene E., Voter, Andrew F., Guo, Song, Keck, James L., Hoffmann, F. Michael, Wildman, Scott A., Gitter, Anthony

“…Traditional small-molecule drug discovery is a time-consuming and costly endeavor. High-throughput chemical screening can only assess a tiny fraction of…”
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