Search Results - "AMSON, R"
-
1
Exosome secretion, including the DNA damage-induced p53-dependent secretory pathway, is severely compromised in TSAP6 Steap3-null mice
Published in Cell death and differentiation (01-11-2008)“…TSAP6 (tumor suppressor-activated pathway 6), also known as Steap3 , is a direct p53 transcriptional target gene. It regulates protein secretion, for example…”
Get full text
Journal Article -
2
TCTP protects from apoptotic cell death by antagonizing bax function
Published in Cell death and differentiation (01-08-2008)“…Translationally controlled tumor protein (TCTP) is a potential target for cancer therapy. It functions as a growth regulating protein implicated in the…”
Get full text
Journal Article -
3
TCTP as a therapeutic target in melanoma treatment
Published in British journal of cancer (22-08-2017)“…Background: Translationally controlled tumour protein (TCTP) is an antiapoptotic protein highly conserved through phylogeny. Translationally controlled tumour…”
Get full text
Journal Article -
4
SIAH-1 promotes apoptosis and tumor suppression through a network involving the regulation of protein folding, unfolding, and trafficking: identification of common effectors with p53 and p21(Waf1)
Published in Proceedings of the National Academy of Sciences - PNAS (06-07-1999)“…We have previously described biological model systems for studying tumor suppression in which, by using H-1 parvovirus as a selective agent, cells with a…”
Get full text
Journal Article -
5
Siah-1 Binds and Regulates the Function of Numb
Published in Proceedings of the National Academy of Sciences - PNAS (18-12-2001)“…The Drosophila Seven in absentia (Sina) gene product originally was described as a protein that controls cell fate decisions during eye development. Its…”
Get full text
Journal Article -
6
Isolation of 10 Differentially Expressed cDNAs in p53-Induced Apoptosis: Activation of the Vertebrate Homologue of the Drosophila Seven in Absentia Gene
Published in Proceedings of the National Academy of Sciences - PNAS (30-04-1996)“…We report the isolation of 10 differentially expressed cDNAs in the process of apoptosis induced by the p53 tumor suppressor. As a global analytical method, we…”
Get full text
Journal Article -
7
Activation of the Human Homologue of the Drosophila sina Gene in Apoptosis and Tumor Suppression
Published in Proceedings of the National Academy of Sciences - PNAS (20-08-1996)“…Developmentally regulated genes in Drosophila, which are conserved through evolution, are potential candidates for key functions in biological processes such…”
Get full text
Journal Article -
8
The Human Protooncogene Product P33pim is Expressed during Fetal Hematopoiesis and in Diverse Leukemias
Published in Proceedings of the National Academy of Sciences - PNAS (01-11-1989)“…We measured the human pim-1 protooncogene (PIM) expression during fetal development and in hematopoietic malignancies. Our data indicate that during human…”
Get full text
Journal Article -
9
Behavioral Alterations Associated with Apoptosis and Down-Regulation of Presenilin 1 in the Brains of p53-Deficient Mice
Published in Proceedings of the National Academy of Sciences - PNAS (09-05-2000)“…Presenilin 1 (PS1) expression is repressed by the p53 tumor suppressor. As shown herein, wild-type PS1 is an effective antiapoptotic molecule capable of…”
Get full text
Journal Article -
10
SIAH-1 inhibits cell growth by altering the mitotic process
Published in Oncogene (25-11-1999)“…SIAH-1, the human homologue of the drosophila seven in absentia gene, is a p53-p21Waf-1 inducible gene. We report that stable transfection with SIAH-1 of the…”
Get full text
Journal Article -
11
A Model for Tumor Suppression Using H-1 Parvovirus
Published in Proceedings of the National Academy of Sciences - PNAS (15-09-1993)“…A model system is proposed to investigate, at the molecular level, the pathways of tumor suppression. As a tool for the selection of cells with a suppressed…”
Get full text
Journal Article -
12
Identification of the cellular protein encoded by the human Wilms' tumor (WT1) gene
Published in Oncogene (01-12-1992)“…A putative tumor-suppressor gene (wt1) located at chromosome 11p13 and involved in Wilms' tumor development has recently been identified as a zinc finger…”
Get more information
Journal Article -
13
bcr genes and transcripts
Published in Oncogene (01-02-1988)“…Human chronic myelogenous leukemia (CML) is a clonal hematologic disorder. CML is characterized by the t(9:22) chromosome translocation which results in…”
Get more information
Journal Article -
14
TSAP6 Facilitates the Secretion of Translationally Controlled Tumor Protein/Histamine-releasing Factor via a Nonclassical Pathway
Published in The Journal of biological chemistry (29-10-2004)“…Translationally controlled tumor protein (TCTP) is cytoplasmic and structurally related to guanine-nucleotide free chaperones. TCTP (also called…”
Get full text
Journal Article -
15
Translationally Controlled Tumor Protein Is a Target of Tumor Reversion
Published in Proceedings of the National Academy of Sciences - PNAS (26-10-2004)“…By analyzing the gene expression profile between tumor cells and revertant counterparts that have a suppressed malignant phenotype, we previously reported a…”
Get full text
Journal Article -
16
Identification of the human pim-1 gene product as a 33-kilodalton cytoplasmic protein with tyrosine kinase activity
Published in Molecular and Cellular Biology (01-04-1988)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text
Journal Article -
17
Biological Models and Genes of Tumor Reversion: Cellular Reprogramming through tpt1/TCTP and SIAH-1
Published in Proceedings of the National Academy of Sciences - PNAS (12-11-2002)“…Tumor reversion is the process by which some cancer cells lose their malignant phenotype. This study was aimed at defining some of the molecular and phenotypic…”
Get full text
Journal Article -
18
Identification of a 130 Kda bcr related gene product
Published in Oncogene (01-02-1989)“…Human chronic myelogenous leukemia is characterized by a reciprocal translocation between chromosomes 9 and 22. This results in the transfer of the c-abl…”
Get more information
Journal Article -
19
Translationally Controlled Tumor Protein Acts as a Guanine Nucleotide Dissociation Inhibitor on the Translation Elongation Factor eEF1A
Published in Proceedings of the National Academy of Sciences - PNAS (25-11-2003)“…Recently, we demonstrated that the expression levels of the translationally controlled tumor protein (TCTP) were strongly down-regulated at the mRNA and…”
Get full text
Journal Article -
20
Internalization of human T lymphocyte receptors
Published in European journal of immunology (1987)“…Monoclonal antibodies specific to human T lymphocyte receptors are currently being used to define the biochemical structure of these proteins as well as of…”
Get more information
Journal Article