Search Results - "AMOROSO, Maria Rosaria"

TRAP1 controls cell cycle G2–M transition through the regulation of CDK1 and MAD2 expression/ubiquitination by Sisinni, Lorenza, Maddalena, Francesca, Condelli, Valentina, Pannone, Giuseppe, Simeon, Vittorio, Li Bergolis, Valeria, Lopes, Elvira, Piscazzi, Annamaria, Matassa, Danilo Swann, Mazzoccoli, Carmela, Nozza, Filomena, Lettini, Giacomo, Amoroso, Maria Rosaria, Bufo, Pantaleo, Esposito, Franca, Landriscina, Matteo

“…Regulation of tumour cell proliferation by molecular chaperones is still a complex issue. Here, the role of the HSP90 molecular chaperone TRAP1 in cell cycle…”
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Mitochondrial Chaperone Trap1 and the Calcium Binding Protein Sorcin Interact and Protect Cells against Apoptosis Induced by Antiblastic Agents by LANDRISCINA, Matteo, LAUDIERO, Gabriella, ESPOSITO, Franca, MADDALENA, Francesca, AMOROSO, Maria Rosaria, PISCAZZI, Annamaria, COZZOLINO, Flora, MONTI, Maria, GARBI, Corrado, FERSINI, Alberto, PUCCI, Piero

“…TRAP1, a mitochondrial chaperone (Hsp75) with antioxidant and antiapoptotic functions, is involved in multidrug resistance in human colorectal carcinoma cells…”
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TRAP1 is involved in BRAF regulation and downstream attenuation of ERK phosphorylation and cell-cycle progression: a novel target for BRAF-mutated colorectal tumors by Condelli, Valentina, Piscazzi, Annamaria, Sisinni, Lorenza, Matassa, Danilo Swann, Maddalena, Francesca, Lettini, Giacomo, Simeon, Vittorio, Palladino, Giuseppe, Amoroso, Maria Rosaria, Trino, Stefania, Esposito, Franca, Landriscina, Matteo

“…Human BRAF-driven tumors are aggressive malignancies with poor clinical outcome and lack of sensitivity to therapies. TRAP1 is a HSP90 molecular chaperone…”
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Resistance to paclitxel in breast carcinoma cells requires a quality control of mitochondrial antiapoptotic proteins by TRAP1 by Maddalena, Francesca, Sisinni, Lorenza, Lettini, Giacomo, Condelli, Valentina, Matassa, Danilo Swann, Piscazzi, Annamaria, Amoroso, Maria Rosaria, La Torre, Giuseppe, Esposito, Franca, Landriscina, Matteo

“…TRAP1 is a mitochondrial antiapoptotic protein up-regulated in several human malignancies. However, recent evidences suggest that TRAP1 is also localized in…”
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The ribonuclease/angiogenin inhibitor is also present in mitochondria and nuclei by Furia, Adriana, Moscato, Marco, Calì, Gaetano, Pizzo, Elio, Confalone, Elena, Amoroso, Maria Rosaria, Esposito, Franca, Nitsch, Lucio, D’Alessio, Giuseppe

“…The data presented here show for the first time that the protein known as “ribonuclease (RNase) inhibitor” (RI or RNH1) is present not only in the cell…”
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Heat shock proteins, cell survival and drug resistance: The mitochondrial chaperone TRAP1, a potential novel target for ovarian cancer therapy by Landriscina, Matteo, Amoroso, Maria Rosaria, Piscazzi, Annamaria, Esposito, Franca

“…Abstract Background Protein homeostasis is a highly complex network of molecular interactions governing the health and life span of the organism. Molecular…”
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TRAP1 revisited: Novel localizations and functions of a 'next-generation' biomarker (Review) by AMOROSO, MARIA ROSARIA, MATASSA, DANILO SWANN, SISINNI, LORENZA, LETTINI, GIACOMO, LANDRISCINA, MATTEO, ESPOSITO, FRANCA

“…In the last decade, the identification and characterization of novel molecular mechanisms and pathways involving the heat shock protein TRAP1/HSP75 in cancers…”
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Stress-Adaptive Response in Ovarian Cancer Drug Resistance: Role of TRAP1 in Oxidative Metabolism-Driven Inflammation by Amoroso, Maria Rosaria, Matassa, Danilo Swann, Agliarulo, Ilenia, Avolio, Rosario, Maddalena, Francesca, Condelli, Valentina, Landriscina, Matteo, Esposito, Franca

“…Metabolic reprogramming is one of the most frequent stress-adaptive response of cancer cells to survive environmental changes and meet increasing nutrient…”
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TRAP1 controls cell migration of cancer cells in metabolic stress conditions: Correlations with AKT/p70S6K pathways by Agliarulo, Ilenia, Matassa, Danilo Swann, Amoroso, Maria Rosaria, Maddalena, Francesca, Sisinni, Lorenza, Sepe, Leandra, Ferrari, Maria Carla, Arzeni, Diana, Avolio, Rosario, Paolella, Giovanni, Landriscina, Matteo, Esposito, Franca

“…Cell motility is a highly dynamic phenomenon that is essential to physiological processes such as morphogenesis, wound healing and immune response, but also…”
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Targeting TRAP1 as a downstream effector of BRAF cytoprotective pathway: a novel strategy for human BRAF-driven colorectal carcinoma by Condelli, Valentina, Maddalena, Francesca, Sisinni, Lorenza, Lettini, Giacomo, Matassa, Danilo Swann, Piscazzi, Annamaria, Palladino, Giuseppe, Amoroso, Maria Rosaria, Esposito, Franca, Landriscina, Matteo

“…The HSP90 chaperone TRAP1 is translational regulator of BRAF synthesis/ubiquitination, since BRAF down-regulation, ERK signaling inhibition and delay of cell…”
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TRAP1 and the proteasome regulatory particle TBP7 Rpt3 interact in the endoplasmic reticulum and control cellular ubiquitination of specific mitochondrial proteins by Amoroso, M R, Matassa, D S, Laudiero, G, Egorova, A V, Polishchuk, R S, Maddalena, F, Piscazzi, A, Paladino, S, Sarnataro, D, Garbi, C, Landriscina, M, Esposito, F

“…Tumor necrosis factor receptor-associated protein-1 (TRAP1) is a mitochondrial (MITO) antiapoptotic heat-shock protein. The information available on the TRAP1…”
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New insights into TRAP1 pathway by Matassa, Danilo Swann, Amoroso, Maria Rosaria, Maddalena, Francesca, Landriscina, Matteo, Esposito, Franca

“…Tumor Necrosis Factor Receptor-Associated Protein 1 (TRAP1) is a mitochondrial heat shock protein involved in the protection from DNA damages and apoptosis…”
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TRAP1-dependent regulation of p70S6K is involved in the attenuation of protein synthesis and cell migration: Relevance in human colorectal tumors by Matassa, Danilo Swann, Agliarulo, Ilenia, Amoroso, Maria Rosaria, Maddalena, Francesca, Sepe, Leandra, Ferrari, Maria Carla, Sagar, Vinay, D'Amico, Silvia, Loreni, Fabrizio, Paolella, Giovanni, Landriscina, Matteo, Esposito, Franca

“…TNF receptor-associated protein 1 (TRAP1) is an HSP90 chaperone involved in stress protection and apoptosis in mitochondrial and extramitochondrial…”
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Mass Spectrometric/Bioinformatic Identification of a Protein Subset That Characterizes the Cellular Activity of Anticancer Peptides by Genovese, Filippo, Gualandi, Alessandra, Taddia, Laura, Marverti, Gaetano, Pirondi, Silvia, Marraccini, Chiara, Perco, Paul, Pelà, Michela, Guerrini, Remo, Amoroso, Maria Rosaria, Esposito, Franca, Martello, Andrea, Ponterini, Glauco, D’Arca, Domenico, Costi, Maria Paola

“…The preclinical study of the mechanism of action of anticancer small molecules is challenging due to the complexity of cancer biology and the fragmentary…”
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Correction to “Mass Spectrometric/Bioinformatic Identification of a Protein Subset That Characterizes the Cellular Activity of Anticancer Peptides” by Genovese, Filippo, Gualandi, Alessandra, Taddia, Laura, Marverti, Gaetano, Pirondi, Silvia, Marraccini, Chiara, Perco, Paul, Pelà, Michela, Guerrini, Remo, Amoroso, Maria Rosaria, Esposito, Franca, Martello, Andrea, Ponterini, Glauco, D’Arca, Domenico, Costi, Maria Paola

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