Search Results - "AMMANN, Patrick"

One-month spaceflight compromises the bone microstructure, tissue-level mechanical properties, osteocyte survival and lacunae volume in mature mice skeletons by Gerbaix, Maude, Gnyubkin, Vasily, Farlay, Delphine, Olivier, Cécile, Ammann, Patrick, Courbon, Guillaume, Laroche, Norbert, Genthial, Rachel, Follet, Hélène, Peyrin, Françoise, Shenkman, Boris, Gauquelin-Koch, Guillemette, Vico, Laurence

“…The weightless environment during spaceflight induces site-specific bone loss. The 30-day Bion-M1 mission offered a unique opportunity to characterize the…”
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Periostin deficiency increases bone damage and impairs injury response to fatigue loading in adult mice by Bonnet, Nicolas, Gineyts, Evelyne, Ammann, Patrick, Conway, Simon J, Garnero, Patrick, Ferrari, Serge

“…Bone damage removal and callus formation in response to fatigue loading are essential to prevent fractures. Periostin (Postn) is a matricellular protein that…”
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Peri-implant bone adaptations to overloading in rat tibiae: experimental investigations and numerical predictions by Piccinini, Marco, Cugnoni, Joel, Botsis, John, Ammann, Patrick, Wiskott, Anselm

“…Objectives (i) To assess the effects of mechanical overloading on implant integration in rat tibiae, and (ii) to numerically predict peri‐implant bone…”
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Influence of implant angulation and cyclic dislodging on the retentive force of two different overdenture attachments - an in vitro study by Srinivasan, Murali, Schimmel, Martin, Badoud, Isabelle, Ammann, Patrick, Herrmann, François R., Müller, Frauke

“…Objective This in vitro study evaluated the influence of implant angulations on the retentive behavior of two overdenture attachments during cyclic dislodging…”
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Deletion of a Single Allele of the Dkk1 Gene Leads to an Increase in Bone Formation and Bone Mass by Morvan, Frederic, Boulukos, Kim, Clément‐Lacroix, Philippe, Roman, Sergio Roman, Suc‐Royer, Isabelle, Vayssière, Béatrice, Ammann, Patrick, Martin, Patrick, Pinho, Sonia, Pognonec, Philippe, Mollat, Patrick, Niehrs, Christof, Baron, Roland, Rawadi, Georges

“…Wnt/β‐catenin signaling has been proven to play a central role in bone biology. Unexpectedly, the Wnt antagonist Dkk2 is required for terminal osteoblast…”
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Sclerostin-Antibody Treatment Decreases Fracture Rates in Axial Skeleton and Improves the Skeletal Phenotype in Growing oim/oim Mice by Cardinal, Mickaël, Dessain, Alicia, Roels, Thomas, Lafont, Sébastien, Ominsky, Michael S., Devogelaer, Jean-Pierre, Chappard, Daniel, Mabilleau, Guillaume, Ammann, Patrick, Nyssen-Behets, Catherine, Manicourt, Daniel H.

“…In osteogenesis imperfecta (OI), vertebrae brittleness causes thorax deformations and leads to cardiopulmonary failure. As sclerostin-neutralizing antibodies…”
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Strontium Ranelate Treatment Improves Trabecular and Cortical Intrinsic Bone Tissue Quality, a Determinant of Bone Strength by Ammann, Patrick, Badoud, Isabelle, Barraud, Sébastien, Dayer, Romain, Rizzoli, René

“…Beside its influence on determinants of bone strength (geometry, microarchitecture), which is likely to be related to a cellular effect, strontium ranelate…”
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Different Responsiveness of Alveolar and Tibial Bone to Bone Loss Stimuli by Mavropoulos, Anestis, Rizzoli, René, Ammann, Patrick

“…Mandibular and systemic bone loss are poorly associated. We compared the effect of isocaloric protein undernutrition and/or ovariectomy on BMD and…”
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Sclerostin antibody reduces long bone fractures in the oim/oim model of osteogenesis imperfecta by Cardinal, Mickaël, Tys, Janne, Roels, Thomas, Lafont, Sébastien, Ominsky, Michael S., Devogelaer, Jean-Pierre, Chappard, Daniel, Mabilleau, Guillaume, Ammann, Patrick, Nyssen-Behets, Catherine, Manicourt, Daniel H.

“…Osteogenesis imperfecta type III (OI) is a serious genetic condition with poor bone quality and a high fracture rate in children. In a previous study, it was…”
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Strontium Ranelate Improves Bone Resistance by Increasing Bone Mass and Improving Architecture in Intact Female Rats by Ammann, Patrick, Shen, Victor, Robin, Bruno, Mauras, Yves, Bonjour, Jean‐Philippe, Rizzoli, Rene

“…Strontium ranelate given to intact rats at doses up to 900 mg/kg/day increases bone resistance, cortical and trabecular bone volume, micro‐architecture, bone…”
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Effects of ovariectomy on the changes in microarchitecture and material level properties in response to hind leg disuse in female rats by Maïmoun, Laurent, Brennan-Speranza, Tara C, Rizzoli, René, Ammann, Patrick

“…Abstract Background Ovariectomy (OVX) and immobilization are known to decrease bone mineral density and alter its microarchitecture. Their effects on the…”
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Material and nanomechanical properties of bone structural units of cortical and trabecular iliac bone tissues from untreated postmenopausal osteoporotic women by Farlay, Delphine, Falgayrac, Guillaume, Ponçon, Camille, Rizzo, Sébastien, Cortet, Bernard, Chapurlat, Roland, Penel, Guillaume, Badoud, Isabelle, Ammann, Patrick, Boivin, Georges

“…The differences in bone nanomechanical properties between cortical (Ct) and trabecular (Tb) bone remain uncertain, whereas knowing the respective contribution…”
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Rehabilitation of masticatory function improves the alveolar bone architecture of the mandible in adult rats by Mavropoulos, Anestis, Ödman, Anna, Ammann, Patrick, Kiliaridis, Stavros

“…Abstract Masticatory functional changes have been shown to influence the quantity and quality of the alveolar bone during growth. This study was designed to…”
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Selective Modification of Bone Quality by PTH, Pamidronate, or Raloxifene by Brennan, Tara C, Rizzoli, René, Ammann, Patrick

“…Bone strength, a determinant of resistance to fracture, depends on BMD, geometry, microarchitecture, bone turnover rates, and properties of the bone at the…”
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Effects of transgenic Pit-1 overexpression on calcium phosphate and bone metabolism by Suzuki, Atsushi, Ammann, Patrick, Nishiwaki-Yasuda, Keiko, Sekiguchi, Sahoko, Asano, Shogo, Nagao, Shizuko, Kaneko, Ryosuke, Hirabayashi, Masumi, Oiso, Yutaka, Itoh, Mitsuyasu, Caverzasio, Joseph

“…The type III inorganic phosphate (Pi) transporter Pit-1 was previously found to be preferentially expressed in developing long bones. Several studies also…”
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Defective Implant Osseointegration Under Protein Undernutrition: Prevention by PTH or Pamidronate by Dayer, Romain, Badoud, Isabelle, Rizzoli, René, Ammann, Patrick

“…Protein deficiency is associated with impaired titanium osseointegration. We studied whether systemic treatment with PTH or pamidronate could influence the…”
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Intrinsic bone tissue properties in adult rat vertebrae: modulation by dietary protein by Hengsberger, Stefan, Ammann, Patrick, Legros, Brian, Rizzoli, René, Zysset, Philippe

“…Bone strength depends on bone mass, geometry, microarchitecture, and intrinsic tissue quality. Whether intrinsic bone tissue properties could be influenced by…”
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Assessing Fracture Risk and Effects of Osteoporosis Drugs: Bone Mineral Density and Beyond by Davison, K. Shawn, PhD, Kendler, David L., MD, Ammann, Patrick, PhD, Bauer, Douglas C., MD, Dempster, David W., PhD, Dian, Larry, MD, Hanley, David A., MD, Harris, Steven T., MD, McClung, Michael R., MD, Olszynski, Wojciech P., MD, PhD, Yuen, Chui K., MD

“…Abstract Although there have been numerous advances in the assessment of bone strength and fracture risk, the majority of these techniques can only be…”
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Bone reactions to controlled loading of endosseous implants: a pilot study by Wiskott, H. W. Anselm, Cugnoni, Joel, Scherrer, Susanne S., Ammann, Patrick, Botsis, John, Belser, Urs C.

“…Objectives: To validate an experimental setup designed to apply load onto bone tissue using osseointegrated implants in a rabbit model. Specifically, (1) to…”
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Mechanically Driven Counter‐Regulation of Cortical Bone Formation in Response to Sclerostin‐Neutralizing Antibodies by Gerbaix, Maude, Ammann, Patrick, Ferrari, Serge

“…ABSTRACT Sclerostin (Scl) antibodies (Scl‐Ab) potently stimulate bone formation, but these effects are transient. Whether the rapid inhibition of Scl‐Ab…”
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