Search Results - "AMBROS, P. F"

FKHRL1-mediated expression of Noxa and Bim induces apoptosis via the mitochondria in neuroblastoma cells by Obexer, P, Geiger, K, Ambros, P F, Meister, B, Ausserlechner, M J

“…Protein kinase-B (PKB) and its target, the forkhead transcription factor like 1 (FKHRL1)/FoxO3a, have been suggested as regulators of neurotrophin-mediated…”
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International consensus for neuroblastoma molecular diagnostics: report from the International Neuroblastoma Risk Group (INRG) Biology Committee by AMBROS, P. F, AMBROS, M, COHN, S. L, PEARSON, Adj, MARIS, J. M, BRODEUR, G. M, HABER, M, KHAN, J, NAKAGAWARA, A, SCHLEIERMACHER, G, SPELEMAN, F, SPITZ, R, LONDON, W. B

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Prognostic impact of chromosomal aberrations in Ewing tumours by HATTINGER, C. M, PÖTSCHGER, U, AMBROS, P. F, GADNER, H, BETTS, D. R, TARKKANEN, M, SQUIRE, J, ZIELENSKA, M, KIURU-KUHLEFELT, S, KAGER, L, THORNER, P, KNUUTILA, S, NIGGLI, F. K

“…Although greater than 50% of Ewing tumours contain non-random cytogenetic aberrations in addition to the pathognomonic 22q12 rearrangements, little is known…”
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International consensus for neuroblastoma molecular diagnostics: report from the International Neuroblastoma Risk Group (INRG) Biology Committee by Ambros, P F, Ambros, I M, Brodeur, G M, Haber, M, Khan, J, Nakagawara, A, Schleiermacher, G, Speleman, F, Spitz, R, London, W B, Cohn, S L, Pearson, A D J, Maris, J M

“…Neuroblastoma serves as a paradigm for utilising tumour genomic data for determining patient prognosis and treatment allocation. However, before the…”
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The Ewing Family of Tumors -- A Subgroup of Small-Round-Cell Tumors Defined by Specific Chimeric Transcripts by Delattre, Olivier, Zucman, Jessica, Melot, Thomas, Garau, Xavier Sastre, Zucker, Jean-Michel, Lenoir, Gilbert M, Ambros, Peter F, Sheer, Denise, Turc-Carel, Claude, Triche, Timothy J, Aurias, Alain, Thomas, Gilles

“…Ewing's sarcoma, 1 the second most common malignant bone tumor of children and young adults, is an aggressive osteolytic tumor with a marked propensity for…”
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Predictive potential of testing for bone marrow involvement in Ewing tumor patients by RT‐PCR: A preliminary evaluation by Zoubek, A., Ladenstein, R., Windhager, R., Amann, G., Fischmeister, G., Kager, L., Jugovic, D., Ambros, P. F., Gadner, H., Kovar, H.

“…EWS/ets‐oncogene fusion transcripts can be detected in at least 98% of Ewing tumors [(ET) Ewing sarcoma and peripheral primitive neuroectodermal tumor] by…”
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Comparative genetic study of intratumoral heterogenous MYCN amplified neuroblastoma versus aggressive genetic profile neuroblastic tumors by Berbegall, A P, Villamón, E, Piqueras, M, Tadeo, I, Djos, A, Ambros, P F, Martinsson, T, Ambros, I M, Cañete, A, Castel, V, Navarro, S, Noguera, R

“…Intratumoral heterogeneous MYCN amplification (hetMNA) is an unusual event in neuroblastoma with unascertained biological and clinical implications. Diagnosis…”
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Role of Ploidy, Chromosome 1p, and Schwann Cells in the Maturation of Neuroblastoma by Ambros, Ingeborg M, Ambros, Peter F, Zellner, Andrea, Roald, Borghild, Amann, Gabriele, Ladenstein, Ruth, Printz, Dieter, Gadner, Helmut

“…Neuroblastomas are the most common extracerebral solid tumors of infancy and childhood. These embryonal tumors of the sympathetic nervous system are unique…”
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Co-amplification of a novel gene, NAG, with the N-myc gene in neuroblastoma by WIMMER, K, ZHU, X. X, LAMB, B. J, KUICK, R, AMBROS, P. F, KOVAR, H, THORAVAL, D, MOTYKA, S, ALBERTS, J. R, HANASH, S. M

“…Substantial evidence implicates amplification of the N-myc gene with aggressive tumor growth and poor outcome in neuroblastoma. However some evidence suggests…”
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Influence of segmental chromosome abnormalities on survival in children over the age of 12 months with unresectable localised peripheral neuroblastic tumours without MYCN amplification by Defferrari, R, Mazzocco, K, Ambros, I M, Ambros, P F, Bedwell, C, Beiske, K, Bénard, J, Berbegall, A P, Bown, N, Combaret, V, Couturier, J, Erminio, G, Gambini, C, Garaventa, A, Gross, N, Haupt, R, Kohler, J, Jeison, M, Lunec, J, Marques, B, Martinsson, T, Noguera, R, Parodi, S, Schleiermacher, G, Tweddle, D A, Valent, A, Van Roy, N, Vicha, A, Villamon, E, Tonini, G P

“…Background: The prognostic impact of segmental chromosome alterations (SCAs) in children older than 1 year, diagnosed with localised unresectable neuroblastoma…”
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Survival from locally invasive or widespread neuroblastoma without cytotoxic therapy by Kushner, B H, Cheung, N K, LaQuaglia, M P, Ambros, P F, Ambros, I M, Bonilla, M A, Gerald, W L, Ladanyi, M, Gilbert, F, Rosenfield, N S, Yeh, S D

“…To test the hypothesis that cytotoxic therapy is not needed at diagnosis to assure the survival of most patients with non-stage 4 neuroblastoma. Patients with…”
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Treatment of localised resectable neuroblastoma. Results of the LNESG1 study by the SIOP Europe Neuroblastoma Group by De Bernardi, B, Mosseri, V, Rubie, H, Castel, V, Foot, A, Ladenstein, R, Laureys, G, Beck-Popovic, M, de Lacerda, A F, Pearson, A D J, De Kraker, J, Ambros, P F, de Rycke, Y, Conte, M, Bruzzi, P, Michon, J

“…Main objective of this study was to confirm that surgery alone is an effective and safe treatment for localised resectable neuroblastoma except stage 2 with…”
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Combined Automatic Immunological and Molecular Cytogenetic Analysis Allows Exact Identification and Quantification of Tumor Cells in the Bone Marrow by MEHES, Gabor, LUEGMAYR, Andrea, AMBROS, Inge M, LADENSTEIN, Ruth, AMBROS, Peter F

“…Purpose: To improve the detection of disseminated tumor cells in bone marrow (BM) and peripheral blood samples of solid tumor patients, a novel…”
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Amplification of CDK4 and MDM2: a detailed study of a high-risk neuroblastoma subgroup by Martinez-Monleon, Angela, Kryh Öberg, Hanna, Gaarder, Jennie, Berbegall, Ana P., Javanmardi, Niloufar, Djos, Anna, Ussowicz, Marek, Taschner-Mandl, Sabine, Ambros, Inge M., Øra, Ingrid, Sandstedt, Bengt, Beiske, Klaus, Ladenstein, Ruth, Noguera, Rosa, Ambros, Peter F., Gordon Murkes, Lena, Ljungman, Gustaf, Kogner, Per, Fransson, Susanne, Martinsson, Tommy

“…In neuroblastoma, MYCN amplification and 11q-deletion are important, although incomplete, markers of high-risk disease. It is therefore relevant to…”
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Prognostic impact of deletions at 1p36 and numerical aberrations in Ewing tumors by Hattinger, C.M., Rumpler, S., Strehl, S., Ambros, I.M., Zoubek, A., Pötschger, U., Gadner, H., Ambros, P.F.

“…Ewing's sarcoma, peripheral primitive neuroectodermal tumors, and Askin tumors are referred to as Ewing tumors (ETs), and are characterized by high MIC2…”
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Disseminated choriocarcinoma in infancy is curable by chemotherapy and delayed tumour resection by Blohm, M.E.G, Calaminus, G, Gnekow, A.K, Heidemann, P.H, Bolkenius, M, Weinel, P, von Schweinitz, D, Ambros, P.F, Schneider, D.T, Harms, D, Göbel, U

“…Infantile choriocarcinoma has a poor prognosis with only 2 surviving children reported in the literature. 2 additional successfully treated children are…”
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A novel putative tyrosine kinase receptor with oncogenic potential by Janssen, J W, Schulz, A S, Steenvoorden, A C, Schmidberger, M, Strehl, S, Ambros, P F, Bartram, C R

“…We have detected transforming activity by a tumorigenicity assay using NIH3T3 cells transfected with DNA from a chronic myeloproliferative disorder patient…”
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Unequivocal identification of disseminated tumor cells in the bone marrow by combining immunological and genetic approaches - functional and prognostic information by AMBROS, P. F, MEHES, G, HATTINGER, C, AMBROS, I. M, LUEGMAYR, A, LADENSTEIN, R, GADNER, H

“…The detection and quantification of disseminated tumor cells (DTC) present in the bone marrow (BM), peripheral blood (PB), and aphereis products (AP) and…”
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DEC1 expression in 1p-aberrant oligodendroglial neoplasms by Preusser, M, Birner, P, Ambros, I M, Ambros, P F, Budka, H, Harris, A L, Hainfellner, J A

“…Expression of hypoxia-related tissue factors in 1p-aberrant oligodendroglial neoplasms diminishes patient outcome. Differentiated embryo-chondrocyte expressed…”
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International neuroblastoma staging system stage 1 neuroblastoma: a prospective study and literature review by Kushner, B H, Cheung, N K, LaQuaglia, M P, Ambros, P F, Ambros, I M, Bonilla, M A, Ladanyi, M, Gerald, W L

“…To gain insight into the management of non-metastatic neuroblastoma by examining clinical and biologic features of International Neuroblastoma Staging System…”
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