Search Results - "AMBATI, J"

Alu RNA accumulation induces epithelial-to-mesenchymal transition by modulating miR-566 and is associated with cancer progression by Di Ruocco, F, Basso, V, Rivoire, M, Mehlen, P, Ambati, J, De Falco, S, Tarallo, V

“…Alu sequences are the most abundant short interspersed repeated elements in the human genome. Here we show that in a cell culture model of colorectal cancer…”
Get full text

Target-independent suppression of angiogenesis by human IgG1 antibodies and IVIg via FcγRI by De Falco, S, Cicatiello, V, Tudisco, L, Tarallo, V, Apicella, I, Ambati, J

Get full text

Are intravitreal injections essential during the COVID-19 pandemic? Global preferred practice patterns and practical recommendations by Tan, A C S, Schwartz, R, Anaya, D, Chatziralli, I, Yuan, M, Cicinelli, M V, Faes, L, Mustapha, M, Phasukkijwatana, N, Pohlmann, D, Reynolds, R, Rosenblatt, A, Savastano, A, Touhami, S, Vaezi, K, Ventura, C V, Vogt, D, Ambati, J, de Smet, M D, Loewenstein, A

“…Tertiary outpatient ophthalmology clinics are high-risk environments for COVID-19 transmission, especially retina clinics, where regular follow-up is needed…”
Get full text

Engineered silica nanocarriers as a high-payload delivery vehicle for antioxidant enzymes by Ambati, J., Lopez, A.M., Cochran, D., Wattamwar, P., Bean, K., Dziubla, T.D., Rankin, S.E.

“…Antioxidant enzymes for the treatment of oxidative stress-related diseases remain a highly promising therapeutic approach. As poor localization and stability…”
Get full text

Exploration of bulk and epitaxy defects in 4H-SiC using large scale optical characterization by Leonard, R. T., Paisley, M. J., Bubel, S., Sumakeris, J. J., Powell, A. R., Khlebnikov, Y., Seaman, J. C., Ambati, J., Burk, A. A., O'Loughlin, M. J., Balkas, E.

“…In this work, aggregate epitaxial carrot distributions are observed at the crystal, wafer and dislocation defect levels, instead of individual extended carrot…”
Get full text

Immunology of age-related macular degeneration by Ambati, Jayakrishna, Atkinson, John P., Gelfand, Bradley D.

“…Key Points Age-related macular degeneration (AMD) is the leading cause of blindness in elderly individuals in the developed world. It features a progressive…”
Get full text

ME and Retinal Disease by AMBATI, J

“…not provided…”
Get full text

Diced Alu: Canning the blinding inflammasome by AMBATI, J

“…Purpose To determine the mechanisms of retinal pigmented epithelium (RPE) cell death induced by DICER1 deficient and Alu RNA accumulation, which are observed…”
Get full text

Drusen complement components C3a and C5a promote choroidal neovascularization by Nozaki, M., Raisler, B.J., Sakurai, E., Sarma, J.V., Barnum, S.R., Lambris, J.D., Chen, Y., Zhang, K., Ambati, B.K., Baffi, J.Z., Ambati, J.

“…The earliest clinical hallmark of age-related macular degeneration (AMD) is the presence of drusen, extracellular deposits that accumulate beneath the retinal…”
Get full text

Anterior uveitis associated with intravenous cidofovir use in patients with cytomegalovirus retinitis by Ambati, Jayakrishna, Wynne, Kevin B, Angerame, Mary C, Robinson, Michael R

“…AIM Intravenous cidofovir is used to treat cytomegalovirus (CMV) retinitis, and has been reported to cause anterior uveitis. Relations were sought between this…”
Get full text

Dynamics of knowledge and attitudes about AIDS among the educated in southern India by Ambati, B. K., Ambati, J., Rao, A. M.

“…AIDS awareness and attitudes among an educated segment of the Indian population were assessed. The study population was a total of 433 students and faculty in…”
Get full text

Drusen Complement Components C3a and C5a Promote Choroidal Neovascularization by Nozaki, Miho, Raisler, Brian J., Sakurai, Eiji, Sarma, J. Vidya, Barnum, Scott R., Lambris, John D., Chen, Yali, Zhang, Kang, Ambati, Balamurali K., Baffi, Judit Z., Ambati, Jayakrishna

“…Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in industrialized nations, affecting 30-50 million people worldwide. The…”
Get full text

Macrophage Depletion Inhibits Experimental Choroidal Neovascularization by Sakurai, Eiji, Anand, Akshay, Ambati, Balamurali K, van Rooijen, Nico, Ambati, Jayakrishna

“…To investigate the role of macrophages in the development of laser-induced choroidal neovascularization (CNV) by selective depletion with liposomal clodronate…”
Get full text

279 - Target-independent suppression of angiogenesis by human IgG1 antibodies and IVIg via FcγRI by De Falco, S., Cicatiello, V., Tudisco, L., Tarallo, V., Apicella, I., Ambati, J.

Get full text

Age-Related Macular Degeneration: Etiology, Pathogenesis, and Therapeutic Strategies by Ambati, Jayakrishna, Ambati, Balamurali K, Yoo, Sonia H, Ianchulev, Sean, Adamis, Anthony P

“…Age-related macular degeneration is the principal cause of registered legal blindness among those aged over 65 in the United States, western Europe, Australia,…”
Get full text

In Vivo Bioimaging of RPE cell death by AMBATI, J, KLEINMAN, ME

“…We have now demonstrated the ability to non‐invasively image RPE cell death in a targeted fashion with a custom engineered NIRF dye conjugated to an…”
Get full text

Do urinary levels of vascular endothelial growth factor predict proliferative retinopathy? by D'Angio, Carl T., Ambati, Jayakrishna, Phelps, Dale L.

“…PURPOSE. Vascular endothelial growth factor (VEGF) is elevated in the vitreous of patients with proliferative retinopathies (PR). Angiogenic factors like VEGF…”
Get full text

An animal model of age-related macular degeneration in senescent Ccl-2- or Ccr-2-deficient mice by Ambati, Jayakrishna, Anand, Akshay, Fernandez, Stefan, Sakurai, Eiji, Lynn, Bert C, Kuziel, William A, Rollins, Barrett J, Ambati, Balamurali K

“…The study and treatment of age-related macular degeneration (AMD), a leading cause of blindness, has been hampered by a lack of animal models. Here we report…”
Get full text

Protein C and protein S deficiency associated with retinal, optic nerve, and cerebral ischaemia by AMBATI, JAYAKRISHNA, HANUCH, OMAR E, BRESNICK, GEORGE H

“…CASE REPORT A 47 year old woman with non-insulin dependent diabetes mellitus with documented absence of previous retinopathy presented with blurring of vision…”
Get full text

HMGB1 is a potent inducer of choroidal angiogenesis through a MyD88‐dependent manner by KIM, Y, KERUR, N, LI, S, AMBATI, J

“…High‐mobility group box 1 (HMGB1) is an endogenous alarm sensor against extracellular damage signals and initiates TLR (toll‐like receptor) responses closely…”
Get full text