Search Results - "AMARAL, Flavio A"

Transient TLR activation restores inflammatory response and ability to control pulmonary bacterial infection in germfree mice by Fagundes, Caio T, Amaral, Flávio A, Vieira, Angélica T, Soares, Adriana C, Pinho, Vanessa, Nicoli, Jacques R, Vieira, Leda Q, Teixeira, Mauro M, Souza, Danielle G

“…Mammals are colonized by an astronomical number of commensal microorganisms on their environmental exposed surfaces. These symbiotic species build up a complex…”
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Resolving inflammation by TAM receptor activation by Vago, Juliana P., Amaral, Flávio A., van de Loo, Fons A.J.

“…The control of inflammation is strictly regulated to ensure the adequate intensity and duration of an inflammatory response, enabling the removal of the…”
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The CXCL8/IL-8 chemokine family and its receptors in inflammatory diseases by Russo, Remo C, Garcia, Cristiana C, Teixeira, Mauro M, Amaral, Flavio A

“…Chemokines are small proteins that control several tissue functions, including cell recruitment and activation under homeostatic and inflammatory conditions…”
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Neutrophils and arthritis: Role in disease and pharmacological perspectives by Fattori, Victor, Amaral, Flavio A., Verri, Waldiceu A.

“…[Display omitted] The inflammatory response in the joint can induce an intense accumulation of leukocytes in the tissue that frequently results in severe local…”
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Annexin A1 promotes timely resolution of inflammation in murine gout by Galvão, Izabela, Vago, Juliana P., Barroso, Livia C., Tavares, Luciana P., Queiroz‐Junior, Celso M., Costa, Vivian V., Carneiro, Fernanda S., Ferreira, Tatiana P., Silva, Patricia M. R., Amaral, Flávio A., Sousa, Lirlândia P., Teixeira, Mauro M.

“…Gout is a self‐limited inflammatory disease caused by deposition of monosodium urate (MSU) crystals in the joints. Resolution of inflammation is an active…”
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Transmembrane TNF‐α is sufficient for articular inflammation and hypernociception in a mouse model of gout by Amaral, Flávio A., Bastos, Leandro F. S., Oliveira, Thiago H. C., Dias, Ana C. F., Oliveira, Vívian L. S., Tavares, Lívia D., Costa, Vivian V., Galvão, Izabela, Soriani, Frederico M., Szymkowski, David E., Ryffel, Bernhard, Souza, Danielle G., Teixeira, Mauro M.

“…Gout manifests as recurrent episodes of acute joint inflammation and pain due to the deposition of monosodium urate (MSU) crystals within the affected tissue…”
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Serum Amyloid A1 (SAA1) Revisited: Restricted Leukocyte-Activating Properties of Homogeneous SAA1 by Abouelasrar Salama, Sara, De Bondt, Mirre, De Buck, Mieke, Berghmans, Nele, Proost, Paul, Oliveira, Vivian Louise Soares, Amaral, Flavio A, Gouwy, Mieke, Van Damme, Jo, Struyf, Sofie

“…Infection, sterile injury, and chronic inflammation trigger the acute phase response in order to re-establish homeostasis. This response includes production of…”
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Neutrophils: Beneficial and Harmful Cells in Septic Arthritis by Boff, Daiane, Crijns, Helena, Teixeira, Mauro M, Amaral, Flavio A, Proost, Paul

“…Septic arthritis is an inflammatory joint disease that is induced by pathogens such as . Infection of the joint triggers an acute inflammatory response…”
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Role of the Chemokine Receptor CXCR2 in Bleomycin-Induced Pulmonary Inflammation and Fibrosis by Russo, Remo C, Guabiraba, Rodrigo, Garcia, Cristiana C, Barcelos, Luciola S, Roffe, Ester, Souza, Adriano L. S, Amaral, Flavio A, Cisalpino, Daniel, Cassali, Geovanni D, Doni, Andrea, Bertini, Riccardo, Teixeira, Mauro M

“…Pulmonary fibrosis is characterized by chronic inflammation and excessive collagen deposition. Neutrophils are thought to be involved in the pathogenesis of…”
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The chemokine fragment CXCL9(74–103) diminishes neutrophil recruitment and joint inflammation in antigen‐induced arthritis by Boff, Daiane, Crijns, Helena, Janssens, Rik, Vanheule, Vincent, Menezes, Gustavo B., Macari, Soraia, Silva, Tarcilia A., Amaral, Flavio A., Proost, Paul

“…This study investigates if treatment with a peptide corresponding to the 30 C‐terminal amino acids of CXCL9, CXCL9(74–103), ameliorates joint inflammation in a…”
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IFN-γ production depends on IL-12 and IL-18 combined action and mediates host resistance to dengue virus infection in a nitric oxide-dependent manner by Fagundes, Caio T, Costa, Vivian V, Cisalpino, Daniel, Amaral, Flávio A, Souza, Patrícia R S, Souza, Rafael S, Ryffel, Bernhard, Vieira, Leda Q, Silva, Tarcília A, Atrasheuskaya, Alena, Ignatyev, George, Sousa, Lirlândia P, Souza, Danielle G, Teixeira, Mauro M

“…Dengue is a mosquito-borne disease caused by one of four serotypes of Dengue virus (DENV-1-4). Severe dengue infection in humans is characterized by…”
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Adapting to environmental stresses: the role of the microbiota in controlling innate immunity and behavioral responses by Fagundes, Caio T., Amaral, Flávio A., Teixeira, Antônio L., Souza, Danielle G., Teixeira, Mauro M.

“…Mammals are subject to colonization by an astronomical number of mutualistic and commensal microorganisms on their environmental exposed surfaces. These…”
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Microbiota-Induced Antibodies Are Essential for Host Inflammatory Responsiveness to Sterile and Infectious Stimuli by Cisalpino, Daniel, Fagundes, Caio T, Brito, Camila B, Ascenção, Fernando R, Queiroz-Junior, Celso M, Vieira, Angélica T, Sousa, Lirlândia P, Amaral, Flávio A, Vieira, Leda Q, Nicoli, Jacques R, Teixeira, Mauro M, Souza, Danielle G

“…The indigenous intestinal microbiota is frequently considered an additional major organ of the human body and exerts profound immunomodulating activities…”
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Essential Role of Platelet-Activating Factor Receptor in the Pathogenesis of Dengue Virus Infection by Souza, Danielle G., Fagundes, Caio T., Sousa, Lirfandia P., Amaral, Flavio A., Souza, Rafael S., Souza, Adriano L., Kroon, Erna G., Sachs, Daniela, Cunha, Fernando Q., Bukin, Eugenij, Atrasheuskaya, Alena, Ignatyev, George, Teixeira, Mauro M., Ferreira, Sérgio Henrique

“…Severe dengue infection in humans causes a disease characterized by thrombocytopenia, increased levels of cytokines, increased vascular permeability,…”
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Selective Increment of Synovial Soluble TYRO3 Correlates with Disease Severity and Joint Inflammation in Patients with Rheumatoid Arthritis by van de Loo, Fons A., Amaral, Flávio A., van Lent, Peter L. E. M., Koenders, Marije I., Thurlings, Rogier M., Waterborg, Claire E. J., Vago, Juliana Priscila, Vullings, Julia, van der Kraan, Peter M.

“…Objective. To investigate the role of TAM receptors in rheumatoid arthritis (RA) by determining synovial tissue TAM receptor expression, synovial fluid levels…”
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Contribution of macrophage migration inhibitory factor to the pathogenesis of dengue virus infection by Assunção-Miranda, Iranaia, Amaral, Flavio A, Bozza, Fernando A, Fagundes, Caio T, Sousa, Lirlandia P, Souza, Danielle G, Pacheco, Patrícia, Barbosa-Lima, Giselle, Gomes, Rachel N, Bozza, Patrícia T, Da Poian, Andrea T, Teixeira, Mauro M, Bozza, Marcelo T

“…Dengue fever is an emerging viral disease transmitted by arthropods to humans in tropical countries. Dengue hemorrhagic fever (DHF) is escalating in frequency…”
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Biological Characterization of Commercial Recombinantly Expressed Immunomodulating Proteins Contaminated with Bacterial Products in the Year 2020: The SAA3 Case by Struyf, Sofie, De Buck, Mieke, Van Damme, Jo, Amaral, Flavio A., Oliveira, Sergio C., Oliveira, Vívian Louise S. de, Gouwy, Mieke, Berghmans, Nele, De Bondt, Mirre, Abouelasrar Salama, Sara, Proost, Paul

“…The serum amyloid A (SAA) gene family is highly conserved and encodes acute phase proteins that are upregulated in response to inflammatory triggers. Over the…”
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The Required Role of Endogenously Produced Lipoxin A4 and Annexin-1 for the Production of IL-10 and Inflammatory Hyporesponsiveness in Mice by Souza, Danielle G, Fagundes, Caio T, Amaral, Flavio A, Cisalpino, Daniel, Sousa, Lirlandia P, Vieira, Angelica T, Pinho, Vanessa, Nicoli, Jacques R, Vieira, Leda Q, Fierro, Iolanda M, Teixeira, Mauro M

“…The appropriate development of an inflammatory response is central for the ability of a host to deal with any infectious insult. However, excessive, misplaced,…”
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Tissue- and Stimulus-Dependent Role of Phosphatidylinositol 3-Kinase Isoforms for Neutrophil Recruitment Induced by Chemoattractants In Vivo by Pinho, Vanessa, de Castro Russo, Remo, Amaral, Flavio A, de Sousa, Lirlandia P, Barsante, Michele M, de Souza, Danielle G, Alves-Filho, Jose C, Cara, Denise C, Hayflick, Joel S, Rommel, Christian, Ruckle, Thomas, Rossi, Adriano G, Teixeira, Mauro M

“…PI3K plays a fundamental role in regulating neutrophil recruitment into sites of inflammation but the role of the different isoforms of PI3K remains unclear…”
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The Long Pentraxin PTX3 Is Crucial for Tissue Inflammation after Intestinal Ischemia and Reperfusion in Mice by Souza, Danielle G, Amaral, Flavio A, Fagundes, Caio T, Coelho, Fernanda M, Arantes, Rosa M.E, Sousa, Lirlandia P, Matzuk, Martin M, Garlanda, Cecília, Mantovani, Alberto, Dias, Adriana A, Teixeira, Mauro M

“…The pentraxin superfamily is a group of evolutionarily conserved proteins that play important roles in the immune system. The long pentraxin PTX3 protein was…”
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