Search Results - "AMAN, M. J"

Assembly of Ebola virus matrix protein VP40 is regulated by latch-like properties of N and C terminal tails by Silva, Leslie P, Vanzile, Michael, Bavari, Sina, Aman, J M Javad, Schriemer, David C

“…The matrix protein VP40 coordinates numerous functions in the viral life cycle of the Ebola virus. These range from the regulation of viral transcription to…”
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Mutation of Jak3 in a Patient with SCID: Essential Role of Jak3 in Lymphoid Development by Russell, Sarah M., Tayebi, Nahid, Nakajima, Hiroshi, Riedy, Mary C., Roberts, Joseph L., Aman, M. Javad, Migone, Thi-Sau, Noguchi, Masayuki, Markert, M. Louise, Buckley, Rebecca H., O'Shea, John J., Leonard, Warren J.

“…Males with X-linked severe combined immunodeficiency (XSCID) have defects in the common cytokine receptor γ chain ($\gamma_c$) gene that encodes a shared,…”
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Ebola VP40 in Exosomes Can Cause Immune Cell Dysfunction by Pleet, Michelle L, Mathiesen, Allison, DeMarino, Catherine, Akpamagbo, Yao A, Barclay, Robert A, Schwab, Angela, Iordanskiy, Sergey, Sampey, Gavin C, Lepene, Benjamin, Nekhai, Sergei, Aman, M J, Kashanchi, Fatah

“…Ebola virus (EBOV) is an enveloped, ssRNA virus from the family capable of causing severe hemorrhagic fever with up to 80-90% mortality rates. The most recent…”
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SHIP inhibits Akt activation in B cells through regulation of Akt membrane localization by Carver, Deborah Jeannean, Aman, Mohammad Javad, Ravichandran, Kodimangalam S.

“…Activation of the serine/threonine kinase Akt and the regulation of its activation are recognized as critical in controlling proliferative/survival signals via…”
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Interferon-α Stimulates Production of Interleukin-10 in Activated CD4+ T Cells and Monocytes by Aman, M. Javad, Tretter, Theresa, Eisenbeis, Nona, Bug, Gesine, Decker, Thomas, Aulitzky, Walter E., Tilg, Herbert, Huber, Christoph, Peschel, Christian

“…In the present study, we investigated the effect of interf eron-α (IFN-α) on the expression of interleukin-10 (IL-10) mRNA and protein synthesis in human…”
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Ebola and Marburg Viruses Replicate in Monocyte-Derived Dendritic Cells without Inducing the Production of Cytokines and Full Maturation by Bosio, Catharine M., Aman, M. Javad, Grogan, Case, Hogan, Robert, Ruthel, Gordon, Negley, Diane, Mohamadzadeh, Mansour, Bavari, Sina, Schmaljohn, Alan

“…Ebola virus (EBOV) and Marburg virus (MARV) cause rapidly progressive hemorrhagic fever with high mortality and may possess specialized mechanisms to evade…”
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The Inositol Phosphatase SHIP Inhibits Akt/PKB Activation in B Cells by Aman, M J, Lamkin, T D, Okada, H, Kurosaki, T, Ravichandran, K S

“…The serine-threonine kinase Akt/PKB is activated downstream of phosphatidylinositol 3-kinase in response to several growth factor stimuli and has been…”
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cDNA cloning and characterization of the human interleukin 13 receptor alpha chain by Aman, M J, Tayebi, N, Obiri, N I, Puri, R K, Modi, W S, Leonard, W J

“…We have cloned cDNAs corresponding to the human interleukin 13 receptor alpha chain (IL-13Ralpha). The protein has 76% homology to murine IL-13Ralpha, with 95%…”
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Regulation of immunomodulatory functions by granulocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factor in vivo by AMAN, M. J, STOCKDREHER, K, THEWS, A, KIENAST, K, AULITZKY, W. E, FÄRBER, L, HAUS, U, KOCI, B, HUBER, C, PESCHEL, C

“…The present study was designed to investigate in vivo immunomodulatory properties of hematopoietic growth factors. The influence on the activation of cytokine…”
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Inhibition of interleukin-11 by interferon-alpha in human bone marrow stromal cells by Aman, M J, Bug, G, Aulitzky, W E, Huber, C, Peschel, C

“…Interleukin-11 (IL-11), which has been detected as a stromal cell-derived cytokine, regulates multiple steps of early hematopoiesis. Synthesis of IL-11 is…”
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Regulation of the cytokine network by interferon: a potential mechanism of interferon in chronic myelogenous leukemia by Peschel, C, Aman, M J, Rudolf, G, Aulitzky, W E, Huber, C

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FcγRIIB1/SHIP-mediated Inhibitory Signaling in B Cells Involves Lipid Rafts by Aman, M. Javad, Tosello-Trampont, Annie-Carole, Ravichandran, Kodimangalam

“…One type of membrane microdomain, enriched in glycosphingolipids and cholesterol and referred to as lipid rafts, has been implicated in the generation of…”
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CIS Associates with the Interleukin-2 Receptor β Chain and Inhibits Interleukin-2-dependent Signaling by Aman, M. Javad, Migone, Thi-Sau, Sasaki, Atsuo, Ascherman, Dana P., Zhu, Ming-hua, Soldaini, Elisabetta, Imada, Kazunori, Miyajima, Atsushi, Yoshimura, Akihiko, Leonard, Warren J.

“…CIS is a cytokine-inducedSH2-containing protein that was originally cloned as an interleukin (IL)-3-inducible gene. CIS is known to associate with the IL-3…”
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IL-2, IL-3, and IFN-gamma differently affect in vivo frequencies of circulating precursors of cytotoxic T lymphocytes (CTL-P) by HLADIK, F, KOLBE, K, IRSCHICK, E. U, AMAN, M. J, GERKEN, G, FÄRBER, L, LIEH, E, PESCHEL, C, AULITZKY, W. E, HUBER, C

“…Experimental animal and human in vivo studies have previously demonstrated the impact of exogenous administration of various cytokines on frequencies of…”
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Lower Antibody Levels to Staphylococcus aureus Exotoxins Are Associated With Sepsis in Hospitalized Adults With Invasive S. aureus Infections by Adhikari, Rajan P., Ajao, Adebola O., Aman, M. Javad, Karauzum, Hatice, Sarwar, Jawad, Lydecker, Alison D., Johnson, J. Kristie, Nguyen, Chinh, Chen, Wilbur H., Roghmann, Mary-Claire

“…Background. Staphylococcus aureus has numerous virulence factors, including exotoxins that may increase the severity of infection. This study was aimed at…”
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Regulation of cytokine expression by interferon-α in human bone marrow stromal cells : inhibition of hematopoietic growth factors and induction of interleukin-1 receptor antagonist by JAVAD AMAN, M, KELLER, U, DERIGS, G, MOHAMADZADEH, M, HUBER, C, PESCHEL, C

“…We investigated the effects of interferon-alpha (IFN-alpha) on the expression of cytokines by human bone marrow stromal cells. Production of…”
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Functional Cleavage of the Common Cytokine Receptor γ Chain (γc) by Calpain by Noguchi, Masayuki, Sarin, Apurva, Aman, M. Javad, Nakajima, Hiroshi, Shores, Elizabeth W., Henkart, Pierre A., Leonard, Warren J.

“…The small subunit of calpain, a calcium-dependent cysteine protease, was found to interact with the cytoplasmic domain of the common cytokine receptor γ chain…”
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Interferon-alpha as an antagonist to proinflammatory and hematopoietic cytokines by Peschel, C, Aman, M J, Huber, C

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Humanlike immune response of human leukocyte antigen-DR3 transgenic mice to staphylococcal enterotoxins: A novel model for superantigen vaccines by DaSilva, Luis, Welcher, Brent C., Ulrich, Robert G., Aman, M. Javad, David, Chella S., Bavari, Sina

“…This study examined the biologic responses of transgenic mice expressing human leukocyte antigen (HLA)-DR3 and human CD4 molecules, in the absence of murine…”
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Cytokine signaling: cytokine-inducible signaling inhibitors by Aman, M J, Leonard, W J

“…Seven members of a family of cytokine-inducible proteins have been identified, a number of which have been shown to act as negative regulators of cytokine…”
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