A Longitudinal Study of the Effect of Placental Extract in the Treatment of Moderate and Moderately Advanced Oral Submucous Fibrosis

Oral Submucous Fibrosis is a premalignant condition of the oral cavity having a malignant transformation rate of 2.3 to 7.6. It is strongly associated with areca nut chewing habit. Clinical features include progressive trismus of soft tissues of oral cavity due to fibrosis of the sub mucosa. Patient...

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Bibliographic Details
Published in:	RGUHS Journal of Dental Sciences Vol. 5; no. 1
Main Authors:	AC, Raj, A, Jayaprasad, AM, Manasa, DD, Darshan, A, Ambili
Format:	Journal Article
Language:	English
Published:	2013
Online Access:	Get full text
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Summary:	Oral Submucous Fibrosis is a premalignant condition of the oral cavity having a malignant transformation rate of 2.3 to 7.6. It is strongly associated with areca nut chewing habit. Clinical features include progressive trismus of soft tissues of oral cavity due to fibrosis of the sub mucosa. Patient suffers from difficulty in opening mouth difficulty in chewing speaking swallowing and inability to have spicy food. There are wide array of treatment modalities but no treatment is effective in reverting the fibrosis. Aqueous extract of the human placenta is shown to have antiinflammatory effect and inhibits mucosal damage. This clinical study is conducted to evaluate the efficacy of placental extract injection in moderate and moderately advanced form of Oral submucous fibrosis.
ISSN:	0976-9439
DOI:	10.26463/rjds.5_1_11