Search Results - "ALWARD, W. L. M"

Acute Hepatitis B Virus Infection: Relation of Age to the Clinical Expression of Disease and Subsequent Development of the Carrier State by McMahon, Brian J., Alward, Wallace L. M., Hall, David B., Heyward, William L., Bender, Thomas R., Francis, Donald P., Maynard, James E.

“…Yupik Eskimos of southwestern Alaska have the highest known prevalence of hepatitis B virus infection of any general population in the United States…”
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The Long-Term Serological Course of Asymptomatic Hepatitis B Virus Carriers and the Development of Primary Hepatocellular Carcinoma by Alward, Wallace L. M., McMahon, Brian J., Hall, David B., Heyward, William L., Francis, Donald P., Bender, Thomas R.

“…One hundred fifty asymptomatic patients who were carriers of hepatitis B surface antigen (HBsAg) were studied serologically for up to 11.3 years (mean, 6.1…”
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Fluorouracil Filtering Surgery Study One-Year Follow-up

“…Two hundred thirteen patients participated in the Fluorouracil Filtering Surgery Study, a randomized clinical trial, to determine the efficacy and safety of…”
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Non-secretion of mutant proteins of the glaucoma gene myocilin in cultured trabecular meshwork cells and in aqueous humor by JACOBSON, Nasreen, ANDREWS, Michael, ALWARD, W. L. M, STONE, Edwin M, CLARK, Abbot F, SHEFFIELD, Val C, SHEPARD, Allan R, NISHIMURA, Darryl, SEARBY, Charles, FINGERT, John H, HAGEMAN, Greg, MULLINS, Robert, DAVIDSON, Beverly L, KWON, Young H

“…Until recently, very little was known about the molecular mechanisms responsible for the development of glaucoma, a leading cause of blindness worldwide…”
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Medical Management of Glaucoma by Alward, Wallace L.M

“…Glaucoma is the leading cause of irreversible blindness in the world. It is estimated that by the year 2000, 66.8 million people will be affected, of whom 6.7…”
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Identification of a Gene That Causes Primary Open Angle Glaucoma by Stone, Edwin M., Fingert, John H., Wallace L. M. Alward, Nguyen, Thai D., Polansky, Jon R., Sara L. F. Sunden, Nishimura, Darryl, Clark, Abbot F., Nystuen, Arne, Nichols, Brian E., Mackey, David A., Ritch, Robert, Kalenak, Jeffrey W., Craven, E. Randy, Sheffield, Val C.

“…Glaucoma is a major cause of blindness and is characterized by progressive degeneration of the optic nerve and is usually associated with elevated intraocular…”
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Haploinsufficiency of the transcription factors FOXC1 and FOXC2 results in aberrant ocular development by SMITH, R. S, ZABALETA, A, KUME, T, SAVINOVA, O. V, KIDSON, S. H, MARTIN, J. E, NISHIMURA, D. Y, ALWARD, W. L. M, HOGAN, B. L. M, JOHN, S. W. M

“…Anterior segment developmental disorders, including Axenfeld-Rieger anomaly (ARA), variably associate with harmfully elevated intraocular pressure (IOP), which…”
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A novel homeobox gene PITX3 is mutated in families with autosomal-dominant cataracts and ASMD by Murray, Jeffrey C, Semina, Elena V, Ferrell, Robert E, Mintz-Hittner, Helen A, Bitoun, Pierre, Alward, Wallace Lee M, Reiter, Rebecca S, Funkhauser, Carrie, Daack-Hirsch, Sandra

“…We report here the identification of a new human homeobox gene, PITX3, and its involvement in anterior segment mesenchymal dysgenesis (ASMD) and congenital…”
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Cloning and characterization of a novel bicoid -related homeobox transcription factor gene, RIEG , involved in Rieger syndrome by Alward, W. Lee M, Semina, Elena V, Small, Kent W, Datson, Nicole A, Siegel-Bartelt, Jacqueline, Murray, Jeffrey C, Bierke-Nelson, Diane, Reiter, Rebecca, Zabel, Bernhard U, Carey, John C, Bitoun, Pierre, Leysens, Nancy J

“…Rieger syndrome (RIEG) is an autosomal-dominant human disorder that includes anomalies of the anterior chamber of the eye, dental hypoplasia and a protuberant…”
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Clinical Features Associated with Mutations in the Chromosome 1 Open-Angle Glaucoma Gene (GLC1A) by Alward, Wallace L.M, Fingert, John H, Coote, Michael A, Johnson, A. Tim, Lerner, S. Fabian, Junqua, Denise, Durcan, Fiona J, McCartney, Paul J, Mackey, David A, Sheffield, Val C, Stone, Edwin M

“…Glaucoma is a disorder of the optic nerves that is characterized by cupping of the optic-nerve head and loss of peripheral vision. Occasionally, there is also…”
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The forkhead transcription factor gene FKHL7 is responsible for glaucoma phenotypes which map to 6p25 by Sheffield, Val C, Nishimura, Darryl Y, Swiderski, Ruth E, Alward, Wallace L. M, Searby, Charles C, Patil, Shivanand R, Bennet, Steven R, Kanis, Adam B, Gastier, Julie M, Stone, Edwin M

“…A number of different eye disorders with the presence of early-onset glaucoma as a component of the phenotype have been mapped to human chromosome 6p25. These…”
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Nocturnal arterial hypotension and its role in optic nerve head and ocular ischemic disorders by Hayreh, S S, Zimmerman, M B, Podhajsky, P, Alward, W L

“…We measured 24-hour ambulatory blood pressure monitoring and diurnal curve of the intraocular pressure in 166 white patients with anterior ischemic optic…”
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The OPA1 gene and optic neuropathy by Alward, W L M

“…[...]a study of POAG patients found no increase in prevalence of OPA1 gene sequence variations when compared to normal control subjects. 5 Patients with ADOA…”
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The genetics of open-angle glaucoma: The story of GLC1A and myocilin by ALWARD, W. L. M

“…A linkage analysis study was performed on a single large family with juvenile-onset primary open-angle glaucoma (POAG). This led to the recognition that there…”
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Autosomal dominant iris hypoplasia is caused by a mutation in the rieger syndrome (rieg/pitx2) gene by Alward, Wallace L.M., Semina, Elena V., Kalenak, Jeffrey W., Héon, Elise, Sheth, Bhavna P., Stone, Edwin M., Murray, Jeffrey C.

“…To determine whether autosomal dominant iris hypoplasia is caused by mutations in the newly described gene for Rieger syndrome (RIEG/ PITX2). Mutation…”
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Linkage of posterior polymorphous corneal dystrophy to 20q11 by Héon, E, Mathers, W D, Alward, W L, Weisenthal, R W, Sunden, S L, Fishbaugh, J A, Taylor, C M, Krachmer, J H, Sheffield, V C, Stone, E M

“…Posterior polymorphous dystrophy (PPMD) is an autosomal dominant disorder of the cornea that is clinically recognized by the presence of vesicles on the…”
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A randomized study of mitomycin augmentation in combined phacoemulsification and trabeculectomy by Carlson, D W, Alward, W L, Barad, J P, Zimmerman, M B, Carney, B L

“…The purpose of the study is to determine whether the intraoperative application of subconjunctival mitomycin C (MMC), during combined phacoemulsification and…”
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Clinical features and linkage analysis of a family with autosomal dominant juvenile glaucoma by Johnson, A T, Drack, A V, Kwitek, A E, Cannon, R L, Stone, E M, Alward, W L

“…Juvenile glaucoma is an uncommon form of open-angle glaucoma that is usually recognized during childhood or early adulthood and which often has a strong family…”
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Control of Intraocular Pressure After Trabeculectomy by Haynes, William L, Alward, Wallace L.M

“…Control of intraocular pressure (IOP) is the goal of trabeculectomy, and pursuit of this goal does not end with the completion of the surgical procedure…”
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Combined Phacoemulsification, Posterior Chamber Intraocular Lens Implantation, and Trabeculectomy With Mitomycin C by MUNDEN, PAUL M., ALWARD, WALLACE L.M.

“…We evaluated the effectiveness of combined phacoemulsification, posterior chamber intraocular lens implantation, and trabeculectomy with mitomycin C in…”
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