Search Results - "ALVES, Nelson"

The anti-lipidemic drug simvastatin modifies epigenetic biomarkers in the amphipod Gammarus locusta by Alves, Nélson, Neuparth, Teresa, Barros, Susana, Santos, Miguel M.

“…The adverse effects of certain environmental chemicals have been recently associated with the modulation of the epigenome. Although changes in the epigenetic…”
Get full text

Artificial neural networks trained to detect viral and phage structural proteins by Seguritan, Victor, Alves, Jr, Nelson, Arnoult, Michael, Raymond, Amy, Lorimer, Don, Burgin, Jr, Alex B, Salamon, Peter, Segall, Anca M

“…Phages play critical roles in the survival and pathogenicity of their hosts, via lysogenic conversion factors, and in nutrient redistribution, via cell lysis…”
Get full text

Metformin disrupts Danio rerio metabolism at environmentally relevant concentrations: A full life-cycle study by Barros, Susana, Ribeiro, Marta, Coimbra, Ana M., Pinheiro, Marlene, Morais, Hugo, Alves, Nélson, Montes, Rosa, Rodil, Rosario, Quintana, José Benito, Santos, Miguel M., Neuparth, Teresa

“…Metformin (MET), an anti-diabetic pharmaceutical of large-scale consumption, is increasingly detected in surface waters. However, current knowledge on the…”
Get full text

Genomic taxonomy of Vibrios by Thompson, Cristiane C, Vicente, Ana Carolina P, Souza, Rangel C, Vasconcelos, Ana Tereza R, Vesth, Tammi, Alves, Jr, Nelson, Ussery, David W, Iida, Tetsuya, Thompson, Fabiano L

“…Vibrio taxonomy has been based on a polyphasic approach. In this study, we retrieve useful taxonomic information (i.e. data that can be used to distinguish…”
Get full text

In Silico Comparative Study of Human and Porcine Amylin by Alves, Nelson A, Frigori, Rafael B

“…Islet transplantation is a promising treatment for type 2 diabetes, but its success is impaired by progressive graft loss, likely due to cytotoxic aggregation…”
Get full text

Functional, biochemical and molecular impact of sediment plumes from deep-sea mining on Mytilus galloprovincialis under hyperbaric conditions by Pinheiro, Marlene, Oliveira, Adriana, Barros, Susana, Alves, Nélson, Raimundo, Joana, Caetano, Miguel, Coimbra, João, Neuparth, Teresa, Santos, Miguel M.

“…The deep-sea is the biggest ecosystem in the world and despite the extreme conditions that characterize it, is highly biodiverse and complex. Deep-sea mining…”
Get full text

Structural Interconversion in Alzheimer’s Amyloid-β(16–35) Peptide in an Aqueous Solution by Alves, Nelson A, Frigori, Rafael B

“…Structural properties of Aβ(16–35) fragment are investigated as a model for the amyloid-β peptide excluding its coil-inducing terminals. Our replica-exchange…”
Get full text

The high stability of the three-helix bundle UBA domain of p62 protein as revealed by molecular dynamics simulations by Teixeira, André L., Alves, Nelson A.

“…The ubiquitin-associated (UBA) domain is an important motif in the modulation of many molecular functionalities. It has been mainly associated with…”
Get full text

Screening of Contaminants of Emerging Concern in Surface Water and Wastewater Effluents, Assisted by the Persistency-Mobility-Toxicity Criteria by Montes, Rosa, Méndez, Sandra, Carro, Nieves, Cobas, Julio, Alves, Nelson, Neuparth, Teresa, Santos, Miguel Machado, Quintana, José Benito, Rodil, Rosario

“…Contaminants of emerging concern (CECs) are compounds of diverse origins that have not been deeply studied in the past which are now accruing growing…”
Get full text

Featuring ACE2 binding SARS-CoV and SARS-CoV-2 through a conserved evolutionary pattern of amino acid residues by Carvalho, Patrícia P. D., Alves, Nelson A.

“…Spike (S) glycoproteins mediate the coronavirus entry into the host cell. The S1 subunit of S-proteins contains the receptor-binding domain (RBD) that is able…”
Get full text

Low-latency perception in off-road dynamical low visibility environments by Ferreira Neto, Nelson Alves, Ruiz, Marco, Reis, Marco, Cajahyba, Tiago, Oliveira, Davi, Barreto, Ana C., Simas Filho, Eduardo F., de Oliveira, Wagner L.A., Schnitman, Leizer, Monteiro, Roberto L.S.

“…Robust systems are required for autonomous driving on non-uniform terrain commonly found in open-pit mines and developing countries. To help narrow the gap in…”
Get full text

Occurrence of Biased Conformations as Precursors of Assembly States in Fibril Elongation of Amyloid‑β Fibril Variants: An In Silico Study by Frigori, Rafael B, Barroso da Silva, Fernando L, Carvalho, Patrícia P. D, Alves, Nelson A

“…We investigate the prevalence, and so the role in the amyloidogenesis, of biased conformations in large ensembles of monomeric forms for Aβ42 and Aβ40 that can…”
Get full text

Chronic exposure to environmentally relevant levels of simvastatin disrupts zebrafish brain gene signaling involved in energy metabolism by Barros, Susana, Coimbra, Ana M., Alves, Nélson, Pinheiro, Marlene, Quintana, José Benito, Santos, Miguel M., Neuparth, Teresa

“…Simvastatin (SIM), a hypocholesterolaemic drug belonging to the statins group, is a widely prescribed pharmaceutical for prevention of cardiovascular diseases…”
Get full text

Genomic and proteomic analyses of the coral pathogen Vibrio coralliilyticus reveal a diverse virulence repertoire by de O Santos, Eidy, Alves, Nelson, Dias, Graciela M, Mazotto, Ana Maria, Vermelho, Alane, Vora, Gary J, Wilson, Bryan, Beltran, Victor H, Bourne, David G, Le Roux, Frédérique, Thompson, Fabiano L

“…Vibrio coralliilyticus has been implicated as an important pathogen of coral species worldwide. In this study, the nearly complete genome of Vibrio…”
Get full text

Unveiling community structures in weighted networks by Alves, Nelson A

“…Random walks on simple graphs in connection with electrical resistor networks lead to the definition of Markov chains with transition probability matrix in…”
Get full text

Synergistic long-range effects of mutations underlie aggregation propensities of amylin analogues by Alves, Nelson A., Dias, Luis G., Frigori, Rafael B.

“…The USFDA has approved pramlintide, commercially named Symlin (sIAPP), as adjunctive therapy for type 2 diabetes (T2D). This analogue of the human amylin…”
Get full text

Higher Electrical Conductivity of Functionalized Graphene Oxide Doped with Silver and Copper (II) Ions by Pereira, Nelson Gustavo Alves, Gonzaléz, Maria Elena Leyva, Queiroz, Alvaro Antonio Alencar de, Oliveira, Adhimar Flávio, Tavares Wanderley Neto, Estácio

“…This study presents a new methodology for graphene oxide (GO) synthesis through electrochemical exfoliation of graphite, followed by phthalic anhydride…”
Get full text

Microcanonical thermostatistics of coarse-grained proteins with amyloidogenic propensity by Frigori, Rafael B, Rizzi, Leandro G, Alves, Nelson A

“…The formation of fibrillar aggregates seems to be a common characteristic of polypeptide chains, although the observation of these aggregates may depend on…”
Get more information

Comparative genomic analyses identify the Vibrio harveyi genome sequenced strains BAA-1116 and HY01 as Vibrio campbellii by Lin, Baochuan, Wang, Zheng, Malanoski, Anthony P., O'Grady, Elizabeth A., Wimpee, Charles F., Vuddhakul, Varaporn, Alves Jr, Nelson, Thompson, Fabiano L., Gomez-Gil, Bruno, Vora, Gary J.

“…Summary Three notable members of the Harveyi clade, Vibrio harveyi, Vibrio alginolyticus and Vibrio parahaemolyticus, are best known as marine pathogens of…”
Get full text

Smoothing switched control laws for uncertain nonlinear systems subject to actuator saturation by Alves, Uiliam Nelson L. T., Teixeira, Marcelo C. M., de Oliveira, Diogo R., Cardim, Rodrigo, Assunção, Edvaldo, de Souza, Wallysonn A.

“…Summary This paper considers a class of uncertain nonlinear systems exactly described by Takagi–Sugeno (T‐S) fuzzy models, with or without matched…”
Get full text