Search Results - "ALTMEYER, Ralf"

Evaluation of Small Molecule Combinations against Respiratory Syncytial Virus In Vitro by Gao, Yuzhen, Cao, Jingjing, Xing, Pan, Altmeyer, Ralf, Zhang, Youming

“…Respiratory syncytial virus (RSV) is a major pathogen that causes severe lower respiratory tract infection in infants, the elderly and the immunocompromised…”
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Anti-Severe Acute Respiratory Syndrome Coronavirus Spike Antibodies Trigger Infection of Human Immune Cells via a pH- and Cysteine Protease-Independent FcγR Pathway by JAUME, Martial, YIP, Ming S, NAL, Beatrice, DAËRON, Marc, BRUZZONE, Roberto, MALIK PEIRIS, J. S, CHEUNG, Chung Y, LEUNG, Hiu L, LI, Ping H, KIEN, Francois, DUTRY, Isabelle, CALLENDRET, Benoit, ESCRIOU, Nicolas, ALTMEYER, Ralf

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Efficient assembly and secretion of recombinant subviral particles of the four dengue serotypes using native prM and E proteins by Wang, Pei-Gang, Kudelko, Mateusz, Lo, Joanne, Siu, Lewis Yu Lam, Kwok, Kevin Tsz Hin, Sachse, Martin, Nicholls, John M, Bruzzone, Roberto, Altmeyer, Ralf M, Nal, Béatrice

“…Flavivirus infected cells produce infectious virions and subviral particles, both of which are formed by the assembly of prM and E envelope proteins and are…”
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Characterization of the major bacterial-fungal populations colonizing dandruff scalps in Shanghai, China, shows microbial disequilibrium by Wang, Lili, Clavaud, Cécile, Bar-Hen, Avner, Cui, Meng, Gao, Jun, Liu, Yuanyuan, Liu, Chen, Shibagaki, Nakako, Guéniche, Audrey, Jourdain, Roland, Lan, Ke, Zhang, Chiyu, Altmeyer, Ralf, Breton, Lionel

“…Dandruff is a scalp disorder characterized by the formation of flaky white‐yellowish scales due to an altered proliferation and differentiation status; a…”
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Screening antivirals with a mCherry-expressing recombinant bovine respiratory syncytial virus: a proof of concept using cyclopamine by Fix, Jenna, Descamps, Delphyne, Galloux, Marie, Ferret, Cécile, Bouguyon, Edwige, Zohari, Siamak, Näslund, Katarina, Hägglund, Sara, Altmeyer, Ralf, Valarcher, Jean-François, Riffault, Sabine, Eléouët, Jean-François

“…Bovine respiratory syncytial virus (BRSV) is a pathogenic pneumovirus and a major cause of acute respiratory infections in calves. Although different vaccines…”
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Cleavage of the SARS coronavirus spike glycoprotein by airway proteases enhances virus entry into human bronchial epithelial cells in vitro by Kam, Yiu-Wing, Okumura, Yuushi, Kido, Hiroshi, Ng, Lisa F P, Bruzzone, Roberto, Altmeyer, Ralf

“…Entry of enveloped viruses into host cells requires the activation of viral envelope glycoproteins through cleavage by either intracellular or extracellular…”
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Seroepidemiology of enterovirus A71 infection in prospective cohort studies of children in southern China, 2013-2018 by Yang, Juan, Liao, Qiaohong, Luo, Kaiwei, Liu, Fengfeng, Zhou, Yonghong, Zou, Gang, Huang, Wei, Yu, Shuanbao, Wei, Xianglin, Zhou, Jiaxin, Dai, Bingbing, Qiu, Qi, Altmeyer, Ralf, Hu, Hongan, Paireau, Juliette, Luo, Li, Gao, Lidong, Nikolay, Birgit, Hu, Shixiong, Xing, Weijia, Wu, Peng, van Doorn, H. Rogier, Horby, Peter W., Simmonds, Peter, Leung, Gabriel M., Cowling, Benjamin J., Cauchemez, Simon, Yu, Hongjie

“…Enterovirus A71 (EV-A71)–related hand, foot, and mouth disease (HFMD) imposes a substantial clinical burden in the Asia Pacific region. To inform policy on the…”
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Ezrin interacts with the SARS coronavirus Spike protein and restrains infection at the entry stage by Millet, Jean Kaoru, Kien, François, Cheung, Chung-Yan, Siu, Yu-Lam, Chan, Wing-Lim, Li, Huiying, Leung, Hiu-Lan, Jaume, Martial, Bruzzone, Roberto, Peiris, Joseph S Malik, Altmeyer, Ralf Marius, Nal, Béatrice

“…Entry of Severe Acute Respiratory Syndrome coronavirus (SARS-CoV) and its envelope fusion with host cell membrane are controlled by a series of complex…”
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Virus attachment and entry offer numerous targets for antiviral therapy by Altmeyer, Ralf

“…In 2003 the first virus entry inhibitor, the anti-HIV peptide T20 (Fuzeon, enfuvirtide), was approved for treatment of advanced Human Immunodeficiency Virus…”
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Dendritic-cell-specific ICAM3-grabbing non-integrin is essential for the productive infection of human dendritic cells by mosquito-cell-derived dengue viruses by Navarro-Sanchez, Erika, Altmeyer, Ralf, Amara, Ali, Schwartz, Olivier, Fieschi, Franck, Virelizier, Jean-Louis, Arenzana-Seisdedos, Fernando, Desprès, Philippe

“…Dengue virus (DV) is a mosquito‐borne flavivirus that causes haemorrhagic fever in humans. DV primarily targets immature dendritic cells (DCs) after a bite by…”
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The cytokine and chemokine profiles in patients with hand, foot and mouth disease of different severities in Shanghai, China, 2010 by Zeng, Mei, Zheng, Xiaoyan, Wei, Ruicheng, Zhang, Na, Zhu, Kai, Xu, Bin, Yang, Chun-Hui, Yang, Chun-Fu, Deng, Chaoyang, Pu, Dongbo, Wang, Xiaohong, Altmeyer, Ralf, Leng, Qibin

“…Systemic upregulation of inflammatory cytokines is characteristic of critical severe hand, foot, and mouth disease (HFMD) with pulmonary edema. Thus,…”
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Molecular epidemiology of human enterovirus 71 at the origin of an epidemic of fatal hand, foot and mouth disease cases in Cambodia by Duong, Veasna, Mey, Channa, Eloit, Marc, Zhu, Huachen, Danet, Lucie, Huang, Zhong, Zou, Gang, Tarantola, Arnaud, Cheval, Justine, Perot, Philippe, Laurent, Denis, Richner, Beat, Ky, Santy, Heng, Sothy, Touch, Sok, Sovann, Ly, van Doorn, Rogier, Tan Tran, Thanh, Farrar, Jeremy J, Wentworth, David E, Das, Suman R, Stockwell, Timothy B, Manuguerra, Jean-Claude, Delpeyroux, Francis, Guan, Yi, Altmeyer, Ralf, Buchy, Philippe

“…Human enterovirus 71 (EV-A71) causes hand, foot and mouth disease (HFMD). EV-A71 circulates in many countries and has caused large epidemics, especially in the…”
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DC-SIGN and L-SIGN Are High Affinity Binding Receptors for Hepatitis C Virus Glycoprotein E2 by Lozach, Pierre-Yves, Lortat-Jacob, Hugues, De Lacroix De Lavalette, Agnès, Staropoli, Isabelle, Foung, Steven, Amara, Ali, Houlès, Corinne, Fieschi, Frank, Schwartz, Olivier, Virelizier, Jean-Louis, Arenzana-Seisdedos, Fernando, Altmeyer, Ralf

“…The hepatitis C virus (HCV) genome codes for highly mannosylated envelope proteins, which are naturally retained in the endoplasmic reticulum. We found that…”
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Repurposing of approved drugs from the human pharmacopoeia to target Wolbachia endosymbionts of onchocerciasis and lymphatic filariasis by Johnston, Kelly L., Ford, Louise, Umareddy, Indira, Townson, Simon, Specht, Sabine, Pfarr, Kenneth, Hoerauf, Achim, Altmeyer, Ralf, Taylor, Mark J.

“…[Display omitted] •There is an urgent need to discover a macrofilaricide for filariasis.•The A·WOL approach is to target the Wolbachia bacteria of filarial…”
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C-type Lectins L-SIGN and DC-SIGN Capture and Transmit Infectious Hepatitis C Virus Pseudotype Particles by Lozach, Pierre-Yves, Amara, Ali, Bartosch, Birke, Virelizier, Jean-Louis, Arenzana-Seisdedos, Fernando, Cosset, François-Loïc, Altmeyer, Ralf

“…The molecular mechanisms involved in the hepatic tropism of hepatitis C virus (HCV) have not been identified. We have shown previously that liver-expressed…”
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The approved pediatric drug suramin identified as a clinical candidate for the treatment of EV71 infection-suramin inhibits EV71 infection in vitro and in vivo by Ren, Peijun, Zou, Gang, Bailly, Benjamin, Xu, Shanshan, Zeng, Mei, Chen, Xinsheng, Shen, Liang, Zhang, Ying, Guillon, Patrice, Arenzana-Seisdedos, Fernando, Buchy, Philippe, Li, Jian, von Itzstein, Mark, Li, Qihan, Altmeyer, Ralf

“…Enterovirus 71 (EV71) causes severe central nervous system infections, leading to cardiopulmonary complications and death in young children. There is an urgent…”
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A dominant EV71-specific CD4+ T cell epitope is highly conserved among human enteroviruses by Wei, Ruicheng, Yang, Chunfu, Zeng, Mei, Terry, Frances, Zhu, Kai, Yang, Chunhui, Altmeyer, Ralf, Martin, William, De Groot, Anne S, Leng, Qibin

“…CD4+ T cell-mediated immunity plays a central role in determining the immunopathogenesis of viral infections. However, the role of CD4+ T cells in EV71…”
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H5-Type Influenza Virus Hemagglutinin Is Functionally Recognized by the Natural Killer-Activating Receptor NKp44 by HO, Joanna W, HERSHKOVITZ, Oren, MANDELBOIM, Michal, ALTMEYER, Ralf, MANDELBOIM, Ofer, BRUZZONE, Roberto, PORGADOR, Angel, PEIRIS, Malik, ZILKA, Alon, BAR-ILAN, Ahuva, NAL, Beatrice, CHU, Kid, KUDELKO, Mateusz, YIU WING KAM, ACHDOUT, Hagit

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Chemical combinations elucidate pathway interactions and regulation relevant to Hepatitis C replication by Lee, Margaret S, Lehár, Joseph, Grenier, Jill M, Altmeyer, Ralf, Owens, Christopher M, Borisy, Alexis A, Johansen, Lisa M, Mawhinney, Christina

“…The search for effective Hepatitis C antiviral therapies has recently focused on host sterol metabolism and protein prenylation pathways that indirectly affect…”
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HIV-1 Entry into T-cells Is Not Dependent on CD4 and CCR5 Localization to Sphingolipid-enriched, Detergent-resistant, Raft Membrane Domains by Percherancier, Yann, Lagane, Bernard, Planchenault, Thierry, Staropoli, Isabelle, Altmeyer, Ralf, Virelizier, Jean-Louis, Arenzana-Seisdedos, Fernando, Hoessli, Daniel C, Bachelerie, Françoise

“…The contribution of raft domains to human immunodeficiency virus (HIV) 1 entry was assessed. In particular, we asked whether the CD4 and CCR5 HIV-1 receptors…”
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