Search Results - "ALTMAN, A"

Recent Advances in Transition Metal‐Catalyzed Functionalization of gem‐Difluoroalkenes by Koley, Suvajit, Altman, Ryan A.

“…gem‐Difluorinated alkenes are readily accessible building blocks that can undergo functionalization to provide a broad spectrum of fluorinated and…”
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Guidelines for pre- and intra-operative care in gynecologic/oncology surgery: Enhanced Recovery After Surgery (ERAS®) Society recommendations — Part I by Nelson, G, Altman, A.D, Nick, A, Meyer, L.A, Ramirez, P.T, Achtari, C, Antrobus, J, Huang, J, Scott, M, Wijk, L, Acheson, N, Ljungqvist, O, Dowdy, S.C

“…Highlights • We provide evidence supporting pre- and intra-operative management of patients undergoing gynecologic/oncology surgery. • This guideline will help…”
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Guidelines for postoperative care in gynecologic/oncology surgery: Enhanced Recovery After Surgery (ERAS®) Society recommendations — Part II by Nelson, G, Altman, A.D, Nick, A, Meyer, L.A, Ramirez, P.T, Achtari, C, Antrobus, J, Huang, J, Scott, M, Wijk, L, Acheson, N, Ljungqvist, O, Dowdy, S.C

“…Highlights • We provide evidence supporting postoperative management of patients undergoing gynecologic/oncology surgery. • This guideline will help integrate…”
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Deoxytrifluoromethylation/aromatization of cyclohexan(en)ones to access highly substituted trifluoromethyl arenes by Bhattarai, Pankaj, Abd El-Gaber, Mohammed K., Koley, Suvajit, Altman, Ryan A.

“…Trifluoromethyl arenes (Ar–CF 3 ) are amongst the commonly encountered fluorinated substructures in pharmaceutical, agrochemical, and material sciences…”
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Enhanced recovery after surgery (ERAS®) society guidelines for gynecologic oncology: Addressing implementation challenges - 2023 update by Nelson, G., Fotopoulou, C., Taylor, J., Glaser, G., Bakkum-Gamez, J., Meyer, L.A., Stone, R., Mena, G., Elias, K.M., Altman, A.D., Bisch, S.P., Ramirez, P.T., Dowdy, S.C.

“…Despite evidence supporting its use, many Enhanced Recovery After Surgery (ERAS) recommendations remain poorly adhered to and barriers to ERAS implementation…”
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4,7-Dimethoxy-1,10-phenanthroline:  An Excellent Ligand for the Cu-Catalyzed N-Arylation of Imidazoles by Altman, Ryan A, Buchwald, Stephen L

“…4,7-Dimethoxy-1,10-phenanthroline (L) was found to be an efficient ligand for the copper-catalyzed N-arylation of imidazole with aryl iodides and bromides…”
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Metal-Free Trifluoromethylation of Aromatic and Heteroaromatic Aldehydes and Ketones by Qiao, Yupu, Si, Tuda, Yang, Ming-Hsiu, Altman, Ryan A

“…The ability to convert simple and common substrates into fluoroalkyl derivatives under mild conditions remains an important goal for medicinal and agricultural…”
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Copper-Catalyzed N-Arylation of Imidazoles and Benzimidazoles by Altman, Ryan A, Koval, Erica D, Buchwald, Stephen L

“…4,7-Dimethoxy-1,10-phenanthroline (L1c) was found to be an efficient ligand for the copper-catalyzed N-arylation of imidazoles and benzimidazoles with both…”
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Cobalt-Catalyzed Selective Unsymmetrical Dioxidation of gem-Difluoroalkenes by Orsi, Douglas L, Douglas, Justin T, Sorrentino, Jacob P, Altman, Ryan A

“…gem-Difluoroalkenes represent valuable synthetic handles for organofluorine chemistry; however, most reactions of this substructure proceed through reactive…”
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Connecting remote C–H bond functionalization and decarboxylative coupling using simple amines by de Azambuja, Francisco, Yang, Ming-Hsiu, Feoktistova, Taisiia, Selvaraju, Manikandan, Brueckner, Alexander C., Grove, Markas A., Koley, Suvajit, Cheong, Paul Ha-Yeon, Altman, Ryan A.

“…Transition metal-catalysed C–H functionalization and decarboxylative coupling are two of the most notable synthetic strategies developed in the past 30 years…”
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Copper-Catalyzed Decarboxylative Trifluoromethylation of Allylic Bromodifluoroacetates by Ambler, Brett R, Altman, Ryan A

“…The development of new synthetic fluorination reactions has important implications in medicinal, agricultural, and materials chemistries. Given the prevalence…”
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Monodentate Phosphines Provide Highly Active Catalysts for Pd-Catalyzed CN Bond-Forming Reactions of Heteroaromatic Halides/Amines and (H)N-Heterocycles by Anderson, Kevin W., Tundel, Rachel E., Ikawa, Takashi, Altman, Ryan A., Buchwald, Stephen L.

“…A good alternative: Highly reactive catalysts based on palladium and dialkylbiarylphosphino ligands provide unprecedented reactivity and selectivity in CN…”
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Cu-Catalyzed N- and O-Arylation of 2-, 3-, and 4-Hydroxypyridines and Hydroxyquinolines by Altman, Ryan A, Buchwald, Stephen L

“…With use of Cu-based catalysts, 2- and 4-hydroxypyridines were N-arylated in modest to excellent yields. In the case of 2-hydroxypyridine, the use of…”
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Preparation of Fluoroalkenes via the Shapiro Reaction: Direct Access to Fluorinated Peptidomimetics by Yang, Ming-Hsiu, Matikonda, Siddharth S, Altman, Ryan A

“…Fluoroalkenes represent a useful class of peptidomimetics with distinct biophysical properties. Current preparations of this functional group commonly provide…”
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Follow-up of women with cervical adenocarcinoma in situ treated by conization: A single centre clinical experience by Adolph, L., Mann, A., Liu, X.Q., Roberts, L., Robinson, C., Popowich, S., Dean, E., Kean, S., Fischer, G., Altman, A.D.

“…Hysterectomy has been the historical gold standard final step in the treatment algorithm of adenocarcinoma in situ (AIS) recommended by most North American…”
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Stepwise O‑Atom Transfer in Heme-Based Tryptophan Dioxygenase: Role of Substrate Ammonium in Epoxide Ring Opening by Shin, Inchul, Ambler, Brett R, Wherritt, Daniel, Griffith, Wendell P, Maldonado, Amanda C, Altman, Ryan A, Liu, Aimin

“…Heme-based tryptophan dioxygenases are established immunosuppressive metalloproteins with significant biomedical interest. Here, we synthesized two mechanistic…”
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Longitudinal Changes and Interobserver Variability of Systolic Myocardial Deformation Values in a Prospective Cohort of Healthy Fetuses across Gestation and after Delivery by Maskatia, Shiraz Arif, MD, Pignatelli, Ricardo H., MD, Ayres, Nancy A., MD, Altman, Carolyn A., MD, Sangi-Haghpeykar, Haleh, PhD, Lee, Wesley, MD

“…Background Normative data for fetal myocardial deformation values have not been comprehensively described in a longitudinal cohort. The effect of gestational…”
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Copper-Catalyzed Synthesis of Trifluoroethylarenes from Benzylic Bromodifluoroacetates by Ambler, Brett R, Zhu, Lingui, Altman, Ryan A

“…Trifluoroethylarenes are found in a variety of biologically active molecules, and strategies for accessing this substructure are important for developing…”
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Quality‐of‐life implications of risk‐reducing cancer surgery by Altman, A. M., Hui, J. Y. C., Tuttle, T. M.

“…Background Modern advances in genetic sequencing techniques have allowed for increased availability of genetic testing for hereditary cancer syndromes…”
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Copper-Mediated Deoxygenative Trifluoromethylation of Benzylic Xanthates: Generation of a CCF3 Bond from an O-Based Electrophile by Zhu, Lingui, Liu, Shasha, Douglas, Justin T., Altman, Ryan A.

“…The conversion of an alcohol‐based functional group, into a trifluoromethyl analogue is a desirable transformation. However, few methods are capable of…”
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