Search Results - "ALSTON, K. L"

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  1. 1

    High-level production of alpha-particle-emitting (211)At and preparation of (211)At-labeled antibodies for clinical use by Zalutsky, M R, Zhao, X G, Alston, K L, Bigner, D

    Published in The Journal of nuclear medicine (1978) (01-10-2001)
    “…In vitro and in vivo studies in human glioma models suggest that the antitenascin monoclonal antibody 81C6 labeled with the 7.2-h-half-life alpha-particle…”
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    Journal Article
  2. 2

    Radioiodination of internalizing monoclonal antibodies using N-succinimidyl 5-iodo-3-pyridinecarboxylate by REIST, C. J, GARG, P. K, ALSTON, K. L, BIGNER, D. D, ZALUTSKY, M. R

    Published in Cancer research (Chicago, Ill.) (01-11-1996)
    “…Monoclonal antibodies (mAbs) that internalize following binding to cell-surface receptors require radiolabeling approaches that minimize loss of radioactivity…”
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    Journal Article
  3. 3

    Astatine-211-Labeled Biotin Conjugates Resistant to Biotinidase for Use in Pretargeted Radioimmunotherapy by Foulon, Catherine F, Alston, Kevin L, Zalutsky, Michael R

    Published in Nuclear medicine and biology (01-02-1998)
    “…We report herein the preparation and biological evaluation of two radioastatinated biotin conjugates, (3-[ 211At]astatobenzoyl)norbiotinamide and ((5-[…”
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  4. 4

    Synthesis and Preliminary Biological Evaluation of (3-Iodobenzoyl)norbiotinamide and ((5-Iodo-3-pyridinyl)carbonyl)norbiotinamide:  Two Radioiodinated Biotin Conjugates with Improved Stability by Foulon, Catherine F, Alston, Kevin L, Zalutsky, Michael R

    Published in Bioconjugate chemistry (01-03-1997)
    “…A new class of radioiodinated biotin conjugates is described in which the amido bond between biotin and the labeled prosthetic group is reversed. One…”
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  5. 5

    Enhanced Binding and Inertness to Dehalogenation of α-Melanotropic Peptides Labeled Using N-Succinimidyl 3-Iodobenzoate by Garg, Pradeep K, Alston, Kevin L, Welsh, Philip C, Zalutsky, Michael R

    Published in Bioconjugate chemistry (01-03-1996)
    “…Two peptides of potential utility for targeting melanoma cells, α-melanocyte-stimulating hormone (α-MSH) and its more potent analogue [Nle4,d-Phe7]-α-MSH, were…”
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    Journal Article
  6. 6

    N^e-(3-[I]Iodobenzoyl)-Lys@u5-N^a-maleimido-Gly@u1- GEEEK([I]IB-Mal-D-GEEEK): A Radioiodinated Prosthetic Group Containing Negatively Charged D-Glutamates for Labeling Internalizing Monoclonal Antibodies by Vaidyanathan, G, Alston, K L, Bigner, D D, Zalutsky, M R

    Published in Bioconjugate chemistry (19-07-2006)
    “…Novel methods are needed for the radiohalogenation of cell-internalizing proteins and peptides because rapid loss of label occurs after lysosomal processing…”
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  7. 7

    Catabolism of radioiodinated murine monoclonal antibody F(ab')2 fragment labeled using N-succinimidyl 3-iodobenzoate and Iodogen methods by Garg, Pradeep K, Alston, Kevin L, Zalutsky, Michael R

    Published in Bioconjugate chemistry (01-07-1995)
    “…The F(ab')2 fragment of monoclonal antibody (MAb) Me1-14 was labeled with 125I using the Iodogen method and by reaction with N-succinimidyl…”
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  8. 8

    Catabolism of 4-fluoro-3-iodobenzylguanidine and meta-iodobenzylguanidine by SK-N-SH neuroblastoma cells by Vaidyanathan, Ganesan, Affleck, Donna J, Alston, Kevin L, Welsh, Philip, Zalutsky, Michael R

    Published in Nuclear medicine communications (01-09-2004)
    “…BACKGROUNDA fluorine substituted derivative of meta-iodobenzylguanidine (MIBG), 4-fluoro-3-iodobenzylguanidine (FIBG), is retained in SK-N-SH human…”
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    Journal Article