Search Results - "ALSTON, K. L"
-
1
High-level production of alpha-particle-emitting (211)At and preparation of (211)At-labeled antibodies for clinical use
Published in The Journal of nuclear medicine (1978) (01-10-2001)“…In vitro and in vivo studies in human glioma models suggest that the antitenascin monoclonal antibody 81C6 labeled with the 7.2-h-half-life alpha-particle…”
Get full text
Journal Article -
2
Radioiodination of internalizing monoclonal antibodies using N-succinimidyl 5-iodo-3-pyridinecarboxylate
Published in Cancer research (Chicago, Ill.) (01-11-1996)“…Monoclonal antibodies (mAbs) that internalize following binding to cell-surface receptors require radiolabeling approaches that minimize loss of radioactivity…”
Get full text
Journal Article -
3
Astatine-211-Labeled Biotin Conjugates Resistant to Biotinidase for Use in Pretargeted Radioimmunotherapy
Published in Nuclear medicine and biology (01-02-1998)“…We report herein the preparation and biological evaluation of two radioastatinated biotin conjugates, (3-[ 211At]astatobenzoyl)norbiotinamide and ((5-[…”
Get full text
Journal Article -
4
Synthesis and Preliminary Biological Evaluation of (3-Iodobenzoyl)norbiotinamide and ((5-Iodo-3-pyridinyl)carbonyl)norbiotinamide: Two Radioiodinated Biotin Conjugates with Improved Stability
Published in Bioconjugate chemistry (01-03-1997)“…A new class of radioiodinated biotin conjugates is described in which the amido bond between biotin and the labeled prosthetic group is reversed. One…”
Get full text
Journal Article -
5
Enhanced Binding and Inertness to Dehalogenation of α-Melanotropic Peptides Labeled Using N-Succinimidyl 3-Iodobenzoate
Published in Bioconjugate chemistry (01-03-1996)“…Two peptides of potential utility for targeting melanoma cells, α-melanocyte-stimulating hormone (α-MSH) and its more potent analogue [Nle4,d-Phe7]-α-MSH, were…”
Get full text
Journal Article -
6
N^e-(3-[I]Iodobenzoyl)-Lys@u5-N^a-maleimido-Gly@u1- GEEEK([I]IB-Mal-D-GEEEK): A Radioiodinated Prosthetic Group Containing Negatively Charged D-Glutamates for Labeling Internalizing Monoclonal Antibodies
Published in Bioconjugate chemistry (19-07-2006)“…Novel methods are needed for the radiohalogenation of cell-internalizing proteins and peptides because rapid loss of label occurs after lysosomal processing…”
Get full text
Journal Article -
7
Catabolism of radioiodinated murine monoclonal antibody F(ab')2 fragment labeled using N-succinimidyl 3-iodobenzoate and Iodogen methods
Published in Bioconjugate chemistry (01-07-1995)“…The F(ab')2 fragment of monoclonal antibody (MAb) Me1-14 was labeled with 125I using the Iodogen method and by reaction with N-succinimidyl…”
Get full text
Journal Article -
8
Catabolism of 4-fluoro-3-iodobenzylguanidine and meta-iodobenzylguanidine by SK-N-SH neuroblastoma cells
Published in Nuclear medicine communications (01-09-2004)“…BACKGROUNDA fluorine substituted derivative of meta-iodobenzylguanidine (MIBG), 4-fluoro-3-iodobenzylguanidine (FIBG), is retained in SK-N-SH human…”
Get full text
Journal Article