Search Results - "ALONSO, Pedro L"
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Public health challenges and prospects for malaria control and elimination
Published in Nature medicine (01-02-2013)“…Malaria's death toll has been reduced as a result of global efforts over the last decade. Yet the rise of drug resistance and the plateauing of funding are…”
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malERA: An updated research agenda for malaria elimination and eradication
Published in PLoS medicine (30-11-2017)“…Achieving a malaria-free world presents exciting scientific challenges as well as overwhelming health, equity, and economic benefits. WHO and countries are…”
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A research agenda to underpin malaria eradication
Published in PLoS medicine (01-01-2011)“…The interruption of malaria transmission worldwide is one of the greatest challenges for international health and development communities. The current expert…”
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A multiphase program for malaria elimination in southern Mozambique (the Magude project): A before-after study
Published in PLoS medicine (01-08-2020)“…[...]the south of Mozambique has historically experienced unsuccessful malaria control and elimination attempts using mainly IRS in the 1960s during the Global…”
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Key gaps in the knowledge of Plasmodium vivax , a neglected human malaria parasite
Published in The Lancet infectious diseases (01-09-2009)“…Summary Plasmodium vivax is geographically the most widely distributed cause of malaria in people, with up to 2·5 billion people at risk and an estimated 80…”
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Some lessons for the future from the Global Malaria Eradication Programme (1955-1969)
Published in PLoS medicine (01-01-2011)“…Encouraged by the early success of using dichloro-diphenyl-trichloroethane (DDT) against malaria, the World Health Organization (WHO) embarked on the Global…”
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Intracontinental spread of human invasive Salmonella Typhimurium pathovariants in sub-Saharan Africa
Published in Nature genetics (01-11-2012)“…Gordon Dougan and colleagues report whole-genome sequencing of a global collection of 179 Salmonella Typhimurium isolates, including 129 diverse sub-Saharan…”
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The Global Enteric Multicenter Study (GEMS) of Diarrheal Disease in Infants and Young Children in Developing Countries: Epidemiologic and Clinical Methods of the Case/Control Study
Published in Clinical infectious diseases (15-12-2012)“…Background. Diarrhea is a leading cause of illness and death among children aged <5 years in developing countries. This paper describes the clinical and…”
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Molecular evidence for the localization of Plasmodium falciparum immature gametocytes in bone marrow
Published in Blood (13-02-2014)“…Plasmodium falciparum immature gametocytes are not observed in peripheral blood. However, gametocyte stages in organs such as bone marrow have never been…”
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Sanitation and Hygiene-Specific Risk Factors for Moderate-to-Severe Diarrhea in Young Children in the Global Enteric Multicenter Study, 2007-2011: Case-Control Study
Published in PLoS medicine (03-05-2016)“…Diarrheal disease is the second leading cause of disease in children less than 5 y of age. Poor water, sanitation, and hygiene conditions are the primary…”
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Molecular diversity of Giardia duodenalis in children under 5 years from the Manhiça district, Southern Mozambique enrolled in a matched case-control study on the aetiology of diarrhoea
Published in PLoS neglected tropical diseases (01-01-2021)“…Giardia duodenalis is an enteric parasite commonly detected in children. Exposure to this organism may lead to asymptomatic or symptomatic infection…”
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Resuscitating the Dying Autopsy
Published in PLoS medicine (2016)“…Summary points Despite the relevant information that postmortem examinations can provide, autopsy rates have been declining worldwide in the last few decades…”
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Breast milk and gut microbiota in African mothers and infants from an area of high HIV prevalence
Published in PloS one (26-11-2013)“…Human milk and infant gut microbiota are essential for the immune system maturation and protection against infections. There is scarce information on the…”
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Border malaria: defining the problem to address the challenge of malaria elimination
Published in Malaria journal (21-08-2023)“…Border malaria is frequently cited as an obstacle to malaria elimination and sometimes used as a justification for the failure of elimination. Numerous border…”
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Genomic characterization of the rotavirus G3P[8] strain in vaccinated children, reveals possible reassortment events between human and animal strains in Manhiça District, Mozambique
Published in Frontiers in microbiology (05-06-2023)“…Mozambique introduced the rotavirus vaccine (Rotarix®; GlaxoSmithKline Biologicals, Rixensart, Belgium) in 2015, and since then, the Centro de Investigação em…”
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Effect of mass dihydroartemisinin-piperaquine administration in southern Mozambique on the carriage of molecular markers of antimalarial resistance
Published in PloS one (19-10-2020)“…Mass drug administration (MDA) can rapidly reduce the burden of Plasmodium falciparum (Pf). However, concerns remain about its contribution to select for…”
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Expression Patterns of Plasmodium falciparum Clonally Variant Genes at the Onset of a Blood Infection in Malaria-Naive Humans
Published in mBio (31-08-2021)“…Clonally variant genes (CVGs) play fundamental roles in the adaptation of Plasmodium falciparum to fluctuating conditions of the human host. However, their…”
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Avoiding another lost decade in reducing malaria burden in African infants and young children
Published in The Lancet global health (01-10-2022)Get full text
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Escherichia coli ST131 clones harbouring AggR and AAF/V fimbriae causing bacteremia in Mozambican children: Emergence of new variant of fimH27 subclone
Published in PLoS neglected tropical diseases (01-05-2020)“…Multidrug-resistant Escherichia coli ST131 fimH30 responsible for extra-intestinal pathogenic (ExPEC) infections is globally distributed. However, the…”
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Determinants of linear growth faltering among children with moderate-to-severe diarrhea in the Global Enteric Multicenter Study
Published in BMC medicine (25-11-2019)“…Moderate-to-severe diarrhea (MSD) in the first 2 years of life can impair linear growth. We sought to determine risk factors for linear growth faltering and to…”
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