Search Results - "ALLHORN, Maria"

Structure, Functions, and Physiological Roles of the Lipocalin α1-Microglobulin (A1M) by Bergwik, Jesper, Kristiansson, Amanda, Allhorn, Maria, Gram, Magnus, Åkerström, Bo

“…α 1 -microglobulin (A1M) is found in all vertebrates including humans. A1M was, together with retinol-binding protein and β-lactoglobulin, one of the three…”
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A Novel Assay for Antibody-Dependent Cell-Mediated Cytotoxicity against HIV-1- or SIV-Infected Cells Reveals Incomplete Overlap with Antibodies Measured by Neutralization and Binding Assays by ALPERT, Michael D, HEYER, Lisa N, WILLIAMS, David E. J, HARVEY, Jackson D, GREENOUGH, Thomas, ALLHORN, Maria, EVANS, David T

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Sugar-free Antibodies-The Bacterial Solution to Autoimmunity? by Allhorn, Maria, Collin, Mattias

“…The enzyme EndoS from Streptococcus pyogenes is an immunomodulatory molecule hydrolyzing the conserved glycans in the effector part of immunoglobulin G (IgG)…”
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Binding of the human antioxidation protein α1-microglobulin (A1M) to heparin and heparan sulfate. Mapping of binding site, molecular and functional characterization, and co-localization in vivo and in vitro by Bergwik, Jesper, Kristiansson, Amanda, Larsson, Jörgen, Ekström, Simon, Åkerström, Bo, Allhorn, Maria

“…Heparin and heparan sulfate (HS) are linear sulfated disaccharide polymers. Heparin is found mainly in mast cells, while heparan sulfate is found in connective…”
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Apolipoprotein D is involved in the mechanisms regulating protection from oxidative stress by Ganfornina, Maria D., Do Carmo, Sonia, Lora, Jose M., Torres‐Schumann, Sonia, Vogel, Marci, Allhorn, Maria, González, Constancio, Bastiani, Michael J., Rassart, Eric, Sanchez, Diego

“…Summary Many nervous system pathologies are associated with increased levels of apolipoprotein D (ApoD), a lipocalin also expressed during normal development…”
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Human IgG/Fc gamma R interactions are modulated by streptococcal IgG glycan hydrolysis by Allhorn, Maria, Olin, Anders I, Nimmerjahn, Falk, Collin, Mattias

“…The human pathogen Streptococcus pyogenes produces an endoglycosidase, EndoS that hydrolyzes the chitobiose core of the asparagine-linked glycan on the heavy…”
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Prevention of paraquat-induced apoptosis in human neuronal SH-SY5Y cells by lipocalin-type prostaglandin D synthase by Fujimori, Ko, Fukuhara, Ayano, Inui, Takashi, Allhorn, Maria

“…J. Neurochem. (2012) 120, 279–291. Paraquat is a widely used herbicide that is structurally similar to the known dopaminergic neurotoxicant…”
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Redox properties of the lipocalin α1-microglobulin: Reduction of cytochrome c, hemoglobin, and free iron by Allhorn, Maria, Klapyta, Anna, Åkerström, Bo

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In Vivo Detection and Absolute Quantification of a Secreted Bacterial Factor from Skin Using Molecularly Imprinted Polymers in a Surface Plasmon Resonance Biosensor for Improved Diagnostic Abilities by Ertürk Bergdahl, Gizem, Andersson, Tilde, Allhorn, Maria, Yngman, Sofie, Timm, Rainer, Lood, Rolf

“…In this study, a surface plasmon resonance (SPR) biosensor was developed for the detection and quantification of a secreted bacterial factor (RoxP) from skin…”
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The IgG-specific endoglycosidase EndoS inhibits both cellular and complement-mediated autoimmune hemolysis by Allhorn, Maria, Briceño, Juana G., Baudino, Lucie, Lood, Christian, Olsson, Martin L., Izui, Shozo, Collin, Mattias

“…EndoS from Streptococcus pyogenes is an immunomodulating enzyme that specifically hydrolyzes glycans from human immunoglobulin G and thereby affects antibody…”
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Up-regulation of A1M/α1-microglobulin in skin by heme and reactive oxygen species gives protection from oxidative damage by Olsson, Magnus G, Allhorn, Maria, Larsson, Jörgen, Cederlund, Martin, Lundqvist, Katarina, Schmidtchen, Artur, Sørensen, Ole E, Mörgelin, Matthias, Akerström, Bo

“…During bleeding the skin is subjected to oxidative insults from free heme and radicals, generated from extracellular hemoglobin. The lipocalin…”
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EndoS from Streptococcus pyogenes is hydrolyzed by the cysteine proteinase SpeB and requires glutamic acid 235 and tryptophans for IgG glycan-hydrolyzing activity by Allhorn, Maria, Olsén, Arne, Collin, Mattias

“…The endoglycosidase EndoS and the cysteine proteinase SpeB from the human pathogen Streptococcus pyogenes are functionally related in that they both hydrolyze…”
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Processing of the lipocalin α1-microglobulin by hemoglobin induces heme-binding and heme-degradation properties by Allhorn, Maria, Berggård, Tord, Nordberg, Jonas, Olsson, Martin L., Åkerström, Bo

“…α1-Microglobulin is a 26-kd protein, widespread in plasma and tissues and well-conserved among vertebrates. α1-Microglobulin belongs to the lipocalins, a…”
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A novel enzyme with antioxidant capacity produced by the ubiquitous skin colonizer Propionibacterium acnes by Allhorn, Maria, Arve, Sabine, Brüggemann, Holger, Lood, Rolf

“…The role of the skin microbiota in human health is poorly understood. Here, we identified and characterized a novel antioxidant enzyme produced by the skin…”
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Structure, Functions, and Physiological Roles of the Lipocalin α 1 -Microglobulin (A1M) by Bergwik, Jesper, Kristiansson, Amanda, Allhorn, Maria, Gram, Magnus, Åkerström, Bo

“…α -microglobulin (A1M) is found in all vertebrates including humans. A1M was, together with retinol-binding protein and β-lactoglobulin, one of the three…”
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Platelet transcriptional profile and protein expression in patients with systemic lupus erythematosus: up-regulation of the type I interferon system is strongly associated with vascular disease by Lood, Christian, Amisten, Stefan, Gullstrand, Birgitta, Jönsen, Andreas, Allhorn, Maria, Truedsson, Lennart, Sturfelt, Gunnar, Erlinge, David, Bengtsson, Anders A.

“…Patients with systemic lupus erythematosus (SLE) have a markedly increased risk to develop cardiovascular disease, and traditional cardiovascular risk factors…”
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EndoS and EndoS2 hydrolyze Fc-glycans on therapeutic antibodies with different glycoform selectivity and can be used for rapid quantification of high-mannose glycans by Sjögren, Jonathan, Cosgrave, Eoin F J, Allhorn, Maria, Nordgren, Maria, Björk, Stephan, Olsson, Fredrik, Fredriksson, Sarah, Collin, Mattias

“…Enzymes that affect glycoproteins of the human immune system, and thereby modulate defense responses, are abundant among bacterial pathogens. Two…”
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EndoS2 is a unique and conserved enzyme of serotype M49 group A Streptococcus that hydrolyses N-linked glycans on IgG and α1-acid glycoprotein by Sjögren, Jonathan, Struwe, Weston B, Cosgrave, Eoin F J, Rudd, Pauline M, Stervander, Martin, Allhorn, Maria, Hollands, Andrew, Nizet, Victor, Collin, Mattias

“…Many bacteria have evolved ways to interact with glycosylation functions of the immune system of their hosts. Streptococcus pyogenes [GAS (group A…”
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Human radical scavenger α1-microglobulin protects against hemolysis in vitro and α1-microglobulin knockout mice exhibit a macrocytic anemia phenotype by Kristiansson, Amanda, Bergwik, Jesper, Alattar, Abdul Ghani, Flygare, Johan, Gram, Magnus, Hansson, Stefan R., Olsson, Martin L., Storry, Jill R., Allhorn, Maria, Åkerström, Bo

“…During red blood cell (RBC) lysis hemoglobin and heme leak out of the cells and cause damage to the endothelium and nearby tissue. Protective mechanisms exist;…”
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OP-33 - A1M-035, an improved human recombinant alpha-1-microglobulin, has therapeutic effects in rhabdomyolysis-induced acute kidney injury by Åkerström, Bo, Rosenlöf, Lena, Hägerwall, Anneli, Rutardottir, Sigurbjörg, Ahlstedt, Jonas, Johansson, Maria E, Erlandsson, Lena, Allhorn, Maria, Gram, Magnus

“…Human A1M (alpha-1-microglobulin) is a reductase and radical- and heme-binding protein with physiological antioxidant protective functions. Recombinant human…”
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