Search Results - "ALLEVA, R"

Redox-active and redox-silent compounds: synergistic therapeutics in cancer by Tomasetti, M, Santarelli, L, Alleva, R, Dong, Lan-Feng, Neuzil, J

“…Tumours exhibit higher basal levels of reactive oxygen species (ROS) and altered redox environment compared to normal cells. Excessive level of ROS can be…”
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Fluctuations in populations of subsurface methane oxidizers in coordination with changes in electron acceptor availability by Magnabosco, C, Timmers, P H A, Lau, M C Y, Borgonie, G, Linage-Alvarez, B, Kuloyo, O, Alleva, R, Kieft, T L, Slater, G F, van Heerden, E, Sherwood Lollar, B, Onstott, T C

“…The concentrations of electron donors and acceptors in the terrestrial subsurface biosphere fluctuate due to migration and mixing of subsurface fluids, but the…”
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In vivo supplementation with coenzyme Q10 enhances the recovery of human lymphocytes from oxidative DNA damage by Tomasetti, Marco, Alleva, Renata, Collins, Andrew R.

“…ABSTRACT We investigated the effect of in vitro and in vivo CoQ10 supplementation on the recovery of lymphocytes from oxidative DNA damage. Furthermore, we…”
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α-Tocopheryl succinate and TRAIL selectively synergise in induction of apoptosis in human malignant mesothelioma cells by TOMASETTI, M, RIPPO, M. R, ALLEVA, R, MORETTI, S, ANDERA, L, NEUZIL, J, PROCOPIO, A

“…Malignant mesothelioma (MM) is a fatal type of neoplasia with poor therapeutic prognosis, largely due to resistance to apoptosis. We investigated the apoptotic…”
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Asbestos exposure affects poly(ADP-ribose) polymerase-1 activity: role in asbestos-induced carcinogenesis by TOMASETTI, Marco, AMATI, Monica, NEUZIL, Jiri, BRACCI, Massimo, SANTARELLI, Lory, NOCCHI, Linda, SACCUCCI, Franca, STRAFELLA, Elisabetta, STAFFOLANI, Sara, TARQUINI, Lucia Miria, CARBONARI, Damiano, ALLEVA, Renata, BORGHI, Battista

“…Asbestos is known to induce malignant mesothelioma (MM) and other asbestos-related diseases. It is directly genotoxic by inducing DNA strand breaks and…”
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Coenzyme Q10 enrichment decreases oxidative DNA damage in human lymphocytes by Tomasetti, M, Littarru, G P, Stocker, R, Alleva, R

“…Ubiquinol-10, the reduced form of coenzyme Q10, is a powerful antioxidant in plasma and lipoproteins. It has been suggested that endogenous ubiquinol-10 also…”
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Coenzyme Q blocks biochemical but not receptor‐mediated apoptosis by increasing mitochondrial antioxidant protection by Alleva, Renata, Tomasetti, Marco, Andera, Ladislav, Gellert, Nina, Borghi, Battista, Weber, Christian, Murphy, Michael P., Neuzil, Jiri

“…Generation of free radicals is often associated with the induction and progression of apoptosis. Therefore, antioxidants can prove anti‐apoptotic, and can help…”
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roles of coenzyme Q10 and vitamin E on the peroxidation of human low density lipoprotein subfractions by Alleva, R, Tomasetti, M, Battino, M, Curatola, G, Littarru, G.P, Folkers, K

“…The aim of our study was to investigate the relationships between the levels of coenzyme Q10 (CoQ10) and vitamin E and the levels of hydroperoxide in three…”
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Lymphocyte DNA damage precedes DNA repair or cell death after orthopaedic surgery under general anaesthesia by Alleva, Renata, Tomasetti, Marco, Solenghi, Maria D., Stagni, Francesca, Gamberini, Flavio, Bassi, Alessandra, Fornasari, Pier Maria, Fanelli, Guido, Borghi, Battista

“…Anaesthetics have gained a lot of attention for their potential mutagenic/carcinogenic effects. In the present study we have investigated the genotoxicity of…”
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Coenzyme Q10 levels in idiopathic and varicocele-associated asthenozoospermia by Balercia, G., Arnaldi, G., Fazioli, F., Serresi, M., Alleva, R., Mancini, A., Mosca, F., Lamonica, G. R., Mantero, F., Littarru, G. P.

“…Summary Levels of coenzyme Q10 (CoQ10) and of its reduced and oxidized forms (ubiquinol, QH2, and ubiquinone, Qox) have been determined in sperm cells and…”
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Periodontitis treatment improves systemic lupus erythematosus response to immunosuppressive therapy by Fabbri, Cristiana, Fuller, Ricardo, Bonfá, Eloisa, Guedes, Lissiane K. N., D’Alleva, Paulo Sergio R., Borba, Eduardo F.

“…Periodontal disease (POD) may affect rheumatic diseases severity, but there are no data regarding the effect of its treatment on disease activity in SLE…”
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Oxidation of LDL and their subfractions: kinetic aspects and CoQ10 content by Alleva, R, Tomasetti, M, Bompadre, S, Littarru, G P

“…Coenzyme Q10 in its reduced form, ubiquinol-10, although present in LDL at concentrations considerably lower than that of alpha-tocopherol, exerts a potent…”
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Fluctuations in populations of subsurface methane oxidizers in coordination with changes in electron acceptor availability by Magnabosco, C, Timmers, A.P.H, Lau, Y.M.C, Borgonie, G, Linage-Alvarez, B, Kuloyo, O, Alleva, R, T.Kieft, L, Slater, F.G, Heerden, E. van, Lollar, B. Sherwood, Onstott, T.C

“…The concentrations of electron donors and acceptors in the terrestrial subsurface biosphere fuctuate due to migration and mixing of subsurface fluids, but the…”
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The hamster clock phase-response curve from summerlike light:dark cycles and its role in daily and seasonal timekeeping by Alleva, John J, Alleva, Frederic R

“…We address the subject of entrainment of the hamster clock by the day:night cycle in summer when the sun sets after 6 PM and rises before 6 AM (nights < 12 h)…”
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Reversal of acute theophylline toxicity by calcium channel blockers in dogs and rats by Whitehurst, Virgil E., Joseph, Xavier, Vick, James A., Alleva, Frederic R., Zhang, Jim, Balazs, Tibor

“…Theophylline, widely used in the treatment of pulmonary diseases, has a narrow therapeutic index; the recommended plasma levels being 10–20 μg/ml in humans…”
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Intensive predeposit-hemodilution autologous blood donation and IOBS increase in erythropoietic levels in patients undergoing hip arthroplasty by Borghi, B, Alleva, R, Ghermandi, C, Pratelli, L, Bonini, A M

“…Erythropoietin (EPO) plasma levels were monitored during the perioperative period in 61 consecutive patients (22 males - 39 females), aged 62.5 +/- 9.5 years,…”
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Synergistic inhibition by benzodiazepine and barbiturate drugs of the clock control of ovulation in hamsters by Alleva, J J, Alleva, F R

“…A surge of pituitary luteinizing hormone (LH) into the bloodstream occurs in hamsters every 4 days between 1:30 p.m. and 3 p.m. in response to a signal from a…”
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Abnormalities of plasma lipoprotein composition and fluidity in psoriasis by Ferretti, G, Alleva, R, Taus, M, Simonetti, O, Cinti, B, Offidani, A M, Bossi, G, Curatola, G

“…We have studied the lipoprotein chemical composition and fluidity, using the fluorescence polarization of the probe 1,6-diphenyl-1,3,5-hexatriene (DPH) in two…”
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Coenzyme Q10 enrichment decreases oxidative DNA damage in human lymphocytes by Tomasetti, M, Littarru, G.P, Stocker, R, Alleva, R

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α-Tocopheryl succinate induces DR4 and DR5 expression by a p53-dependent route: Implication for sensitisation of resistant cancer cells to TRAIL apoptosis by Tomasetti, Marco, Andera, Ladislav, Alleva, Renata, Borghi, Battista, Neuzil, Jiri, Procopio, Antonio

“…We evaluated the ability of α-tocopheryl succinate (α-TOS) to sensitise TRAIL-resistant malignant mesothelioma (MM) cells to TRAIL-induced apoptosis. We show…”
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