Search Results - "ALLEN, Michael D"

Subcellular dynamics of protein kinase A activity visualized by FRET-based reporters by Allen, Michael D., Zhang, Jin

“…cAMP-dependent protein kinase (PKA) mediates key cellular processes via compartmentalized activity, and the ability to track its activity in living cells…”
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Visualization of PKA activity in plasma membrane microdomains by Depry, Charlene, Allen, Michael D, Zhang, Jin

“…Membrane rafts are sphingolipid- and cholesterol-rich microdomains that contain dynamic arrangements of signaling proteins. Notably, various components of the…”
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Hit-and-run epigenetic editing prevents senescence entry in primary breast cells from healthy donors by Saunderson, Emily A., Stepper, Peter, Gomm, Jennifer J., Hoa, Lily, Morgan, Adrienne, Allen, Michael D., Jones, J. Louise, Gribben, John G., Jurkowski, Tomasz P., Ficz, Gabriella

“…Aberrant promoter DNA hypermethylation is a hallmark of cancer; however, whether this is sufficient to drive cellular transformation is not clear. To…”
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Prognostic and Therapeutic Impact of Argininosuccinate Synthetase 1 Control in Bladder Cancer as Monitored Longitudinally by PET Imaging by ALLEN, Michael D, PHUONG LUONG, LATTANZIO, Laura, CHMIELEWSKA-KASSASSIR, Malgorzata, TOMLINSON, Ian, ROYLANCE, Rebecca, WHITAKER, Hayley C, WARREN, Anne Y, NEAL, David, FREZZA, Christian, BELTRAN, Luis, JONES, Louise J, HUDSON, Chantelle, CHELALA, Claude, WU, Bor-Wen, BOMALASKI, John S, JACKSON, Robert C, LU, Yong-Jie, CROOK, Tim, LEMOINE, Nicholas R, MATHER, Stephen, FOSTER, Julie, SOSABOWSKI, Jane, LEYTON, Julius, AVRIL, Norbert, LI, Chien-Feng, SZLOSAREK, Peter W, DELAGE, Barbara, GHAZALY, Essam, CUTTS, Rosalind, MING YUAN, SYED, Nelofer, LO NIGRO, Cristiana

“…Targeted therapies have yet to have significant impact on the survival of patients with bladder cancer. In this study, we focused on the urea cycle enzyme…”
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Signaling diversity of PKA achieved via a Ca2+-cAMP-PKA oscillatory circuit by Ni, Qiang, Ganesan, Ambhighainath, Aye-Han, Nwe-Nwe, Gao, Xinxin, Allen, Michael D, Levchenko, Andre, Zhang, Jin

“…PKA initiates and modulates the frequency of oscillations of Ca 2+ and cAMP in insulin-secreting cells and itself oscillates to provide spatiotemporal control…”
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Occupancy of both sites on the thyrotropin (TSH) receptor dimer is necessary for phosphoinositide signaling by Allen, Michael D., Neumann, Susanne, Gershengorn, Marvin C.

“…ABSTRACT The thyroid‐stimulating hormone (TSH) receptor signals via Gs to produce cAMP and via Gq/11 to produce inositol‐1,4,5‐trisphosphate, which is degraded…”
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Rigidity sensing and adaptation through regulation of integrin types by Elosegui-Artola, Alberto, Bazellières, Elsa, Allen, Michael D., Andreu, Ion, Oria, Roger, Sunyer, Raimon, Gomm, Jennifer J., Marshall, John F., Jones, J. Louise, Trepat, Xavier, Roca-Cusachs, Pere

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Between a rock and a hard place: Trace element nutrition in Chlamydomonas by Merchant, Sabeeha S., Allen, Michael D., Kropat, Janette, Moseley, Jeffrey L., Long, Joanne C., Tottey, Stephen, Terauchi, Aimee M.

“…Photosynthetic organisms are among the earliest life forms on earth and their biochemistry is strictly dependent on a wide range of inorganic nutrients owing…”
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A Tunable FRET Circuit for Engineering Fluorescent Biosensors by Allen, Michael D., Zhang, Jin

“…Donor, acceptor, and tuner: FRET‐based ratiometric live‐cell imaging captures emissions of two fluorophores within the constraints of a FRET pair. A method for…”
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Manganese Deficiency in Chlamydomonas Results in Loss of Photosystem II and MnSOD Function, Sensitivity to Peroxides, and Secondary Phosphorus and Iron Deficiency by Allen, Michael D, Kropat, Janette, Tottey, Stephen, Del Campo, José A, Merchant, Sabeeha S

“…For photoheterotrophic growth, a Chlamydomonas reinhardtii cell requires at least 1.7 x 10⁷ manganese ions in the medium. At lower manganese ion concentrations…”
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Mechanostimulation of breast myoepithelial cells induces functional changes associated with DCIS progression to invasion by Hayward, Mary-Kate, Allen, Michael D., Gomm, Jennifer J., Goulding, Iain, Thompson, Clare L., Knight, Martin M., Marshall, John F., Jones, J. Louise

“…Women with ductal carcinoma in situ (DCIS) have an increased risk of progression to invasive breast cancer. Although not all women with DCIS will progress to…”
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Spatiotemporally Regulated Protein Kinase A Activity Is a Critical Regulator of Growth Factor-Stimulated Extracellular Signal-Regulated Kinase Signaling in PC12 Cells by Herbst, Katie J., Allen, Michael D., Zhang, Jin

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Integrin-mediated protein kinase A activation at the leading edge of migrating cells by Lim, Chinten J, Kain, Kristin H, Tkachenko, Eugene, Goldfinger, Lawrence E, Gutierrez, Edgar, Allen, Michael D, Groisman, Alex, Zhang, Jin, Ginsberg, Mark H

“…cAMP-dependent protein kinase A (PKA) is important in processes requiring localized cell protrusion, such as cell migration and axonal path finding. Here, we…”
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TGFβ-mediated MMP13 secretion drives myoepithelial cell dependent breast cancer progression by Gibson, Shayin V., Tomas Bort, Elena, Rodríguez-Fernández, Lucía, Allen, Michael D., Gomm, Jennifer J., Goulding, Iain, auf dem Keller, Ulrich, Agnoletto, Andrea, Brisken, Cathrin, Peck, Barrie, Cameron, Angus J., Marshall, John F., Jones, J. Louise, Carter, Edward P., Grose, Richard P.

“…Ductal carcinoma in situ (DCIS) is a non-obligate precursor of invasive breast cancer. Virtually all women with DCIS are treated, despite evidence suggesting…”
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FEA1, FEA2, and FRE1, Encoding Two Homologous Secreted Proteins and a Candidate Ferrireductase, Are Expressed Coordinately with FOX1 and FTR1 in Iron-Deficient Chlamydomonas reinhardtii by Allen, Michael D, del Campo, José A, Kropat, Janette, Merchant, Sabeeha S

“…Classifications Services EC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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FER1 and FER2 Encoding Two Ferritin Complexes in Chlamydomonas reinhardtii Chloroplasts Are Regulated by Iron by Long, Joanne C, Sommer, Frederik, Allen, Michael D, Lu, Shu-Fen, Merchant, Sabeeha S

“…Two unlinked genes FER1 and FER2 encoding ferritin subunits were identified in the Chlamydomonas genome. An improved FER2 gene model, built on the basis of…”
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Thyrotropin receptor stimulates internalization-independent persistent phosphoinositide signaling by Boutin, Alisa, Allen, Michael D, Geras-Raaka, Elizabeth, Huang, Wenwei, Neumann, Susanne, Gershengorn, Marvin C

“…The thyrotropin [thyroid-stimulating hormone (TSH)] receptor (TSHR) is known to acutely and persistently stimulate cAMP signaling and at higher TSH…”
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The cAMP-dependent protein kinase inhibitor H-89 attenuates the bioluminescence signal produced by Renilla Luciferase by Herbst, Katie J, Allen, Michael D, Zhang, Jin

“…Investigations into the regulation and functional roles of kinases such as cAMP-dependent protein kinase (PKA) increasingly rely on cellular assays. Currently,…”
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The Epstein-Barr Virus-Encoded LMP2A and LMP2B Proteins Promote Epithelial Cell Spreading and Motility by ALLEN, Michael. D, YOUNG, Lawrence S, DAWSON, Christopher W

“…Erratum ( vol. 79 , p. 3889 ) Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious…”
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Rigidity sensing and adaptation through regulation of integrin types by Elosegui-Artola, Alberto, Bazellières, Elsa, Allen, Michael D., Andreu, Ion, Oria, Roger, Sunyer, Raimon, Gomm, Jennifer J., Marshall, John F., Jones, J. Louise, Trepat, Xavier, Roca-Cusachs, Pere

“…Tissue rigidity regulates processes in development, cancer and wound healing. However, how cells detect rigidity, and thereby modulate their behaviour, remains…”
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