Search Results - "ALEXANDER, B. D"

Single-cell atlas of human liver development reveals pathways directing hepatic cell fates by Wesley, Brandon T., Ross, Alexander D. B., Muraro, Daniele, Miao, Zhichao, Saxton, Sarah, Tomaz, Rute A., Morell, Carola M., Ridley, Katherine, Zacharis, Ekaterini D., Petrus-Reurer, Sandra, Kraiczy, Judith, Mahbubani, Krishnaa T., Brown, Stephanie, Garcia-Bernardo, Jose, Alsinet, Clara, Gaffney, Daniel, Horsfall, Dave, Tysoe, Olivia C., Botting, Rachel A., Stephenson, Emily, Popescu, Dorin-Mirel, MacParland, Sonya, Bader, Gary, McGilvray, Ian D., Ortmann, Daniel, Sampaziotis, Fotios, Saeb-Parsy, Kourosh, Haniffa, Muzlifah, Stevens, Kelly R., Zilbauer, Matthias, Teichmann, Sarah A., Vallier, Ludovic

“…The liver has been studied extensively due to the broad number of diseases affecting its vital functions. However, therapeutic advances have been hampered by…”
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Indigenous cattle of Sri Lanka: Genetic and phylogeographic relationship with Zebu of Indus Valley and South Indian origin by L. G. S., Lokugalappatti, Wickramasinghe, Saumya, P. A. B. D., Alexander, Abbas, Kamran, Hussain, Tanveer, Ramasamy, Saravanan, Manomohan, Vandana, Tapsoba, Arnaud Stephane R., Pichler, Rudolf, Babar, Masroor E., Periasamy, Kathiravan

“…The present study reports the population structure, genetic admixture and phylogeography of cattle breeds of Sri Lanka viz. Batu Harak, Thawalam and White…”
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Fungal CYP51 Inhibitors VT-1161 and VT-1129 Exhibit Strong In Vitro Activity against Candida glabrata and C. krusei Isolates Clinically Resistant to Azole and Echinocandin Antifungal Compounds by Schell, W A, Jones, A M, Garvey, E P, Hoekstra, W J, Schotzinger, R J, Alexander, B D

“…The activities of fungal CYP51 inhibitors VT-1161 and VT-1129 were determined for ( = 34) and ( = 50). isolates were screened for FKS gene mutations. All…”
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Correlation of MIC with Outcome for Candida Species Tested against Caspofungin, Anidulafungin, and Micafungin: Analysis and Proposal for Interpretive MIC Breakpoints by Pfaller, M.A, Diekema, D.J, Ostrosky-Zeichner, L, Rex, J.H, Alexander, B.D, Andes, D, Brown, S.D, Chaturvedi, V, Ghannoum, M.A, Knapp, C.C, Sheehan, D.J, Walsh, T.J

“…The CLSI Antifungal Subcommittee followed the M23-A2 "blueprint" to develop interpretive MIC breakpoints for anidulafungin, caspofungin, and micafungin against…”
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Epidemiology of Invasive Mold Infections in Lung Transplant Recipients by Doligalski, C. T., Benedict, K., Cleveland, A. A., Park, B., Derado, G., Pappas, P. G., Baddley, J. W., Zaas, D. W., Harris, M. T., Alexander, B. D.

“…Invasive mold infections (IMIs) are a major source of morbidity and mortality among lung transplant recipients (LTRs), yet information regarding the…”
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Multicenter retrospective development and validation of a clinical prediction rule for nosocomial invasive candidiasis in the intensive care setting by OSTROSKY-ZEICHNER, L, SABLE, C, NUCCI, M, PAPPAS, P. G, BRADLEY, M. E, MAJOR, S, ZIMMER, L, WALLACE, D, DISMUKES, W. E, REX, J. H, SOBEL, J, ALEXANDER, B. D, DONOWITZ, G, KAN, V, KAUFFMAN, C. A, KETT, D, LARSEN, R. A, MORRISON, V

“…The study presented here was performed in order to create a rule that identifies subjects at high risk for invasive candidiasis in the intensive care setting…”
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Infections Due to Scedosporium apiospermum and Scedosporium prolificans in Transplant Recipients: Clinical Characteristics and Impact of Antifungal Agent Therapy on Outcome by Husain, Shahid, Muñoz, Patricia, Forrest, Graeme, Alexander, Barbara D., Somani, Jyoti, Brennan, Kathleen, Wagener, Marilyn M., Singh, Nina

“…Background. Unique characteristics, impact of therapy with antifungal agents, and outcome of infections with Scedosporium species were assessed in transplant…”
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Wild-Type MIC Distribution and Epidemiological Cutoff Values for Aspergillus fumigatus and Three Triazoles as Determined by the Clinical and Laboratory Standards Institute Broth Microdilution Methods by PFALLER, M. A, DIEKEMA, D. J, JOHNSON, E. M, KNAPP, C. C, MOTYL, M. R, OSTROSKY-ZEICHNER, L, SHEEHAN, D. J, WASH, T, GHANNOUM, M. A, REX, J. H, ALEXANDER, B. D, ANDES, D, BROWN, S. D, CHATURVEDI, V, ESPINEL-LNGROFF, A, FOWLER, C. L

“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Multicenter Registry of Patients Receiving Systemic Mold-Active Triazoles for the Management of Invasive Fungal Infections by Ostrosky-Zeichner, L., Nguyen, M. H., Bubalo, J., Alexander, B. D., Miceli, M. H., Pappas, P. G., Jiang, J., Song, Y., Thompson, G. R.

“…Introduction ‘Real-world’ data for mold-active triazoles (MATs) in the treatment of invasive fungal infections (IFIs) are lacking. This study evaluated usage…”
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Survival After Lung Transplantation of Cystic Fibrosis Patients Infected with Burkholderia cepacia Complex by Alexander, B. D., Petzold, E. W., Reller, L. B., Palmer, S. M., Davis, R. D., Woods, C. W., LiPuma, J. J.

“…Within the Burkholderia cepacia complex (Bcc), B. cenocepacia portends increased mortality compared with other species. We investigated the impact of Bcc…”
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Opportunistic Mycelial Fungal Infections in Organ Transplant Recipients: Emerging Importance of Non-Aspergillus Mycelial Fungi by Husain, Shahid, Alexander, Barbara D., Munoz, Patricia, Avery, Robin K., Houston, Sally, Pruett, Timothy, Jacobs, Richard, Dominguez, Edward A., Tollemar, Jan G., Baumgarten, Katherine, Yu, Chen M., Wagener, Marilyn M., Linden, Peter, Kusne, Shimon, Singh, Nina

“…To determine the spectrum and impact of mycelial fungal infections, particularly those due to non-Aspergillus molds, 53 liver and heart transplant recipients…”
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Evaluation of a digital microfluidic real-time PCR platform to detect DNA of Candida albicans in blood by Schell, W. A., Benton, J. L., Smith, P. B., Poore, M., Rouse, J. L., Boles, D. J., Johnson, M. D., Alexander, B. D., Pamula, V. K., Eckhardt, A. E., Pollack, M. G., Benjamin, D. K., Perfect, J. R., Mitchell, T. G.

“…Species of Candida frequently cause life-threatening infections in neonates, transplant and intensive care unit (ICU) patients, and others with compromised…”
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Endemic fungal infections in solid organ and hematopoietic cell transplant recipients enrolled in the Transplant-Associated Infection Surveillance Network (TRANSNET) by Kauffman, C.A., Freifeld, A.G., Andes, D.R., Baddley, J.W., Herwaldt, L., Walker, R.C., Alexander, B.D., Anaissie, E.J., Benedict, K., Ito, J.I., Knapp, K.M., Lyon, G.M., Marr, K.A., Morrison, V.A., Park, B.J., Patterson, T.F., Schuster, M.G., Chiller, T.M., Pappas, P.G.

“…Background Invasive fungal infections are a major cause of morbidity and mortality among solid organ transplant (SOT) and hematopoietic cell transplant (HCT)…”
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The membrane-anchored metalloproteinase regulator RECK stabilizes focal adhesions and anterior-posterior polarity in fibroblasts by Morioka, Y, Monypenny, J, Matsuzaki, T, Shi, S, Alexander, D B, Kitayama, H, Noda, M

“…Accumulating evidence indicates that Reversion-inducing cysteine-rich protein with Kazal motifs (RECK), a membrane-anchored matrix metalloproteinase regulator,…”
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Multicenter Evaluation of a Candida albicans Peptide Nucleic Acid Fluorescent In Situ Hybridization Probe for Characterization of Yeast Isolates from Blood Cultures by Wilson, D. A, Joyce, M. J, Hall, L. S, Reller, L. B, Roberts, G. D, Hall, G. S, Alexander, B. D, Procop, G. W

“…We evaluated aliquots from 244 clinical blood culture bottles that demonstrated yeasts on Gram stain using a Candida albicans peptide nucleic acid (PNA)…”
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Single-Cell Sequencing of Developing Human Gut Reveals Transcriptional Links to Childhood Crohn’s Disease by Elmentaite, Rasa, Ross, Alexander D.B., Roberts, Kenny, James, Kylie R., Ortmann, Daniel, Gomes, Tomás, Nayak, Komal, Tuck, Liz, Pritchard, Sophie, Bayraktar, Omer Ali, Heuschkel, Robert, Vallier, Ludovic, Teichmann, Sarah A., Zilbauer, Matthias

“…Human gut development requires the orchestrated interaction of differentiating cell types. Here, we generate an in-depth single-cell map of the developing…”
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Human Pluripotent Stem Cell-Derived Endoderm for Modeling Development and Clinical Applications by Yiangou, Loukia, Ross, Alexander D.B., Goh, Kim Jee, Vallier, Ludovic

“…The liver, lung, pancreas, and digestive tract all originate from the endoderm germ layer, and these vital organs are subject to many life-threatening diseases…”
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The Membrane-Anchored MMP Inhibitor RECK Is a Key Regulator of Extracellular Matrix Integrity and Angiogenesis by Oh, Junseo, Takahashi, Rei, Kondo, Shunya, Mizoguchi, Akira, Adachi, Eijiro, Sasahara, Regina M., Nishimura, Sachiko, Imamura, Yukio, Kitayama, Hitoshi, Alexander, David B., Ide, Chizuka, Horan, Thomas P., Arakawa, Tsutomu, Yoshida, Hisahito, Nishikawa, Shin-ichi, Itoh, Yoshifumi, Seiki, Motoharu, Itohara, Shigeyoshi, Takahashi, Chiaki, Noda, Makoto

“…Matrix metalloproteinases (MMPs) are essential for proper extracellular matrix remodeling. We previously found that a membrane-anchored glycoprotein, RECK,…”
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Evaluating the efficacy of topical vancomycin powder in the treatment of open lower extremity fractures by Vaida, Justin, Conti, Alexander DB, Ray, Justin J, Bravin, Daniel A, Bramer, Michelle A

“…Introduction Optimal management of lower extremity fractures includes early antibiotics administration, thorough irrigation and debridement, consideration of…”
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Fatal Apophysomyces elegans Infection Transmitted by Deceased Donor Renal Allografts by Alexander, B. D., Schell, W. A., Siston, A. M., Rao, C. Y., Bower, W. A., Balajee, S. A., Howell, D. N., Moore, Z. S., Noble‐Wang, J., Rhyne, J. A., Fleischauer, A. T., Maillard, J. M., Kuehnert, M., Vikraman, D., Collins, B. H., Marroquin, C. E., Park, B. J.

“…Two patients developed renal mucormycosis following transplantation of kidneys from the same donor, a near‐drowning victim in a motor vehicle crash…”
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