Search Results - "ALETRAS, A. J"

Targeting the tumor proteasome as a mechanism to control the synthesis and bioactivity of matrix macromolecules by Skandalis, S S, Aletras, A J, Gialeli, C, Theocharis, A D, Afratis, N, Tzanakakis, G N, Karamanos, N K

“…Extracellular matrices (ECMs) are dynamic structures that provide cells not only with a structural support but, importantly, exhibit significant functional…”
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Diagnostic and classification value of metalloproteinases in squamous human laryngeal carcinoma by Christopoulos, T A, Papageorgakopoulou, N, Theocharis, D A, Aletras, A J, Tsiganos, C P, Papadas, T A, Mastronikolis, N S, Goumas, P, Vynios, D H

“…Metalloproteinases (MMPs) are a class of enzymes largely involved in tumour progression and metastasis. At least twenty different enzymes are recognized that…”
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Gelatinolytic and collagenolytic activity in periprosthetic tissues from loose hip endoprostheses by SYGGELOS, Spyros A, ELEFTHERIOU, Sofia C, GIANNOPOULOU, Eleftheria, PANAGIOTOPOULOS, Elias, ALETRAS, Alexios J

“…OBJECTIVE: To study the contribution of different members of the metalloproteinases (MMP) family in gelatinolytic and collagenolytic potential, namely…”
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A solid-phase assay for quantitative analysis of sulfated glycosaminoglycans at the nanogram level. Application to tissue samples by Vynios, D.H, Faraos, A, Spyracopoulou, G, Aletras, A.J, Tsiganos, C.P

“…A sensitive and accurate solid-phase methodology for the quantitative analysis of glycosaminoglycans is described. Chondroitin-4-sulfate (CSA) was labelled…”
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MIF attenuates the suppressive effect of dexamethasone on IL-6 production by nasal polyp by Stathas, T, Athanassiou, S D, Drakouli, S, Giannopoulou, E, Mastronikolis, N S, Naxakis, S, Aletras, A J

“…Nasal polyposis (NP) is a chronic inflammatory disease of the upper airways, that characterized by inflammatory cells infiltration, extracellular matrix…”
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Dynamics of proteins: light scattering study of dilute and dense colloidal suspensions of eye lens homogenates by Giannopoulou, A, Aletras, A J, Pharmakakis, N, Papatheodorou, G N, Yannopoulos, S N

“…We report a dynamic light scattering study on protein suspensions of bovine lens homogenates at conditions (pH and ionic strength) similar to the physiological…”
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In vitro effects of non-steroidal anti-inflammatory drugs on cytokine, prostanoid and matrix metalloproteinase production by interface membranes from loose hip or knee endoprostheses by Syggelos, S.A., M.D., Ph.D, Giannopoulou, E., Ph.D, Gouvousis, P.A., Ph.D, Andonopoulos, A.P., M.D., Ph.D., F.A.C.P, Aletras, A.J., Ph.D, Panagiotopoulos, E., M.D., Ph.D

“…Summary Objective To study the effects of the non-steroidal anti-inflammatory drugs (NSAIDs) aceclofenac, piroxicam, tenoxicam and indomethacin on cytokine,…”
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Presence of hyaluronidase isoforms in nasal polyps by Hatziri, A, Vynios, D H, Panogeorgou, T, Bouga, H, Triantaphyllidou, I E, Naxakis, S S, Stathas, T, Aletras, A J, Kourousis, C, Mastronikolis, N S

“…Nasal polyps are benign lesions originating from the nasal mucosa or paranasal sinuses. The most important etiological factor seems to be increased hydration…”
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Hypoxia modulates the effects of transforming growth factor-β isoforms on matrix-formation by primary human lung fibroblasts by Papakonstantinou, Eleni, Aletras, Alexios J, Roth, Michael, Tamm, Michael, Karakiulakis, George

“…Chronic hypoxia is implicated in lung fibrosis, which is characterized by enhanced deposition of extracellular matrix (ECM) molecules. Transforming growth…”
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Determination of the HNK-1 epitope (3-sulphated glucuronic acid) in intact chondroitin sulphates by ELISA. Application to squid skin proteoglycans and their oversulphated carbohydrate structures by Karamanos, N K, Aletras, A J, Antonopoulos, C A, Hjerpe, A

“…The reactivity of the HNK-1 monoclonal antibody to chondroitin sulphates and derived disaccharides was studied using an ELISA inhibition test. The antibody…”
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Glutamate-like immunoreactivity in chick cerebellum and optic tectum by VOUKELATOU, G, ALETRAS, A. J, TSOURINAKIS, T, KOUVELAS, E. D

“…Glutamate was coupled via glutaraldehyde to bovine serum albumin. The conjugate was used for raising specific anti-glutamate antibodies. The purified antibody…”
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Extraction and fractionation of proteoglycans from squid skin by Karamanos, N K, Aletras, A J, Antonopoulos, C A, Tsegenidis, T, Tsiganos, C P, Vynios, D H

“…The extractability of squid skin proteoglycans with solutions of varying concentrations of guanidine-HCl, urea and SDS was studied; 4 M guanidine-HCl, being…”
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Identification of L-glutamate binding sites in chick brain by photoaffinity labeling by Voukelatou, G, Aletras, A J, Kouvelas, E D

“…The photoaffinity cross-linker, N-hydroxysuccinimidyl-4-azido benzoate ester, was used to attach L-[3H]glutamate irreversibly to chick brain membranes…”
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Chondroitin proteoglycans from squid skin : isolation, characterization and immunological studies by KARAMANOS, N. K, ALETRAS, A. J, ANTONOPOULOS, C. A, HJERPE, A, TSIGANOS, C. P

“…Two populations of proteochondroitins were isolated from 4 M guanidine hydrochloride extracts of squid skin by a combination of ion exchange, gel…”
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Presence of the HNK-1 epitope (3-sulfoglucuronic acid) on oligosaccharides from squid skin chondroitin proteoglycans and degradation of proteoglycans by proteolytic enzymes by Aletras, A J, Karamanos, N K, Hjerpe, A

“…Using competitive ELISA it was found that chondroitin proteoglycans from the skin of squid, which is a primitive organism, are reactive with the HNK-1…”
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Dynamics of proteins: Light scattering study of dilute and dense colloidal suspensions of eye lens homogenates by Giannopoulou, A, Aletras, A. J, Pharmakakis, N, Papatheodorou, G. N, Yannopoulos, S. N

“…We report a dynamic light scattering study on protein suspensions of bovine lens homogenates at conditions (pH and ionic strength) similar to the physiological…”
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Isolation, characterization and properties of the oversulphated chondroitin sulphate proteoglycan from squid skin with peculiar glycosaminoglycan sulphation pattern by KARAMANOS, Nikos K., ALETRAS, Alexis J., TSEGENIDIS, Theodore, TSIGANOS, Constantine P., ANTONOPOULOS, Christos A.

“…Oversulphated chondroitin sulphate proteoglycan from squid skin was isolated from 4 M guanidine hydrochloride extract by ion‐exchange chromatography, gel…”
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Matrix Metalloproteinases of Epithelial Origin in Facial Sebum of Patients with Acne and their Regulation by Isotretinoin by Papakonstantinou, Eleni, Aletras, Alexios J., Glass, Evelyn, Tsogas, Panagiotis, Dionyssopoulos, Alexander, Adjaye, James, Fimmel, Sabine, Gouvousis, Panagiotis, Herwig, Ralf, Lehrach, Hans, Zouboulis, Christos C., Karakiulakis, George

“…Acne vulgaris is a skin disorder of the sebaceous follicles, involving hyperkeratinization and perifollicular inflammation. Matrix metalloproteinases (MMP)…”
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A novel class of adhesion acidic glycans in sea urchin embryos. Isolation, characterization and immunological studies during early embryonal development by Papakonstantinou, E, Karakiulakis, G, Aletras, A J, Misevic, G N

“…Total glycans were isolated and purified from Lytechinus pictus embryos at early developmental stages by gel-filtration chromatography after pronase and DNase…”
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Isolation and characterization of two glycoproteins from hyaline cartilage by ANAGNOSTIDES, Stavros T., ALETRAS, Alexis J., LYMBERI, Peggy, TSIGANOS, Constantine P.

“…Two acidic glycoproteins of molecular mass 92 kDa and 56 kDa were purified from 4 M guanidine hydrochloride extracts of chick sternal cartilage, by density…”
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