Search Results - "ALBRECHT, Letusa"
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Editorial: New advances in knowledge of the parasite-host relationship during malarial infection
Published in Frontiers in immunology (11-10-2022)Get full text
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Unraveling the Impact of Extracellular Vesicle-Depleted Serum on Endothelial Cell Characteristics over Time
Published in International journal of molecular sciences (01-05-2024)“…Extracellular vesicles (EVs) are produced by all kinds of cells, including endothelial cells. It has been observed that EVs present in fetal bovine serum…”
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A suitable RNA preparation methodology for whole transcriptome shotgun sequencing harvested from Plasmodium vivax-infected patients
Published in Scientific reports (03-03-2021)“…Plasmodium vivax is a world-threatening human malaria parasite, whose biology remains elusive. The unavailability of in vitro culture, and the difficulties in…”
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Plasmodium vivax vaccine: What is the best way to go?
Published in Frontiers in immunology (16-01-2023)“…Malaria is one of the most devastating human infectious diseases caused by spp. parasites. A search for an effective and safe vaccine is the main challenge for…”
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Characterization of T and B cell epitopes in PvCyRPA by studying the naturally acquired immune response in Brazilian Amazon communities
Published in Scientific reports (09-11-2024)“…Plasmodium vivax , a challenging species to eliminate, causes millions of malaria cases globally annually. Developing an effective vaccine is crucial in the…”
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Plasmodium vivax Biology: Insights Provided by Genomics, Transcriptomics and Proteomics
Published in Frontiers in cellular and infection microbiology (08-02-2018)“…During the last decade, the vast omics field has revolutionized biological research, especially the genomics, transcriptomics and proteomics branches, as…”
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Construction, Expression, and Evaluation of the Naturally Acquired Humoral Immune Response against Plasmodium vivax RMC-1, a Multistage Chimeric Protein
Published in International journal of molecular sciences (18-07-2023)“…The PvCelTOS, PvCyRPA, and Pvs25 proteins play important roles during the three stages of the lifecycle. In this study, we designed and expressed a recombinant…”
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Rosettes integrity protects Plasmodium vivax of being phagocytized
Published in Scientific reports (07-10-2020)“…Plasmodium vivax is the most prevalent cause of malaria outside of Africa. P. vivax biology and pathogenesis are still poorly understood. The role of one…”
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Exploring the naturally acquired response to Pvs47 gametocyte antigen
Published in Frontiers in immunology (10-10-2024)“…Malaria represents a challenging global public health task, with being the predominant parasite in Brazil and the most widely distributed species throughout…”
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Immunogenicity of PvCyRPA, PvCelTOS and Pvs25 chimeric recombinant protein of Plasmodium vivax in murine model
Published in Frontiers in immunology (19-06-2024)“…In the Americas, is the predominant causative species of malaria, a debilitating and economically significant disease. Due to the complexity of the malaria…”
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Insights on Rosetting Phenomenon in Plasmodium vivax Malaria
Published in Current clinical microbiology reports (01-03-2021)“…Purpose of Review Information about rosettes in Plasmodium vivax infection is scarce. However, the understanding of this phenomenon is important for…”
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Re-emergence of Gamma-like-II and emergence of Gamma-S:E661D SARS-CoV-2 lineages in the south of Brazil after the 2021 outbreak
Published in Virology journal (17-11-2021)“…We report a genomic surveillance of SARS-CoV-2 lineages circulating in Paraná, southern Brazil, from March 2020 to April 2021. Our analysis, based on 333…”
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Antigenicity and adhesiveness of a Plasmodium vivax VIR-E protein from Brazilian isolates
Published in Memórias do Instituto Oswaldo Cruz (01-01-2021)“…Plasmodium vivax, the major cause of malaria in Latin America, has a large subtelomeric multigene family called vir. In the P. vivax genome, about 20% of its…”
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Plasmodium vivax AMA1: Implications of distinct haplotypes for immune response
Published in PLoS neglected tropical diseases (08-07-2020)“…In Brazil, Plasmodium vivax infection accounts for around 80% of malaria cases. This infection has a substantial impact on the productivity of the local…”
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Rosette formation by Plasmodium vivax gametocytes favors the infection in Anopheles aquasalis
Published in Frontiers in cellular and infection microbiology (15-02-2023)“…a public health problem and the most common type of malaria outside sub-Saharan Africa. The capacity of cytoadhesion, rosetting, and liver latent phase…”
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MicroRNAs in the Host-Apicomplexan Parasites Interactions: A Review of Immunopathological Aspects
Published in Frontiers in cellular and infection microbiology (02-02-2016)“…MicroRNAs (miRNAs), a class of small non-coding regulatory RNAs, have been detected in a variety of organisms ranging from ancient unicellular eukaryotes to…”
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Improved in vitro culture of Plasmodium falciparum permits establishment of clinical isolates with preserved multiplication, invasion and rosetting phenotypes
Published in PloS one (22-07-2013)“…To be able to robustly propagate P. falciparum at optimal conditions in vitro is of fundamental importance for genotypic and phenotypic studies of both…”
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Rheopathologic Consequence of Plasmodium vivax Rosette Formation
Published in PLoS neglected tropical diseases (10-08-2016)“…Malaria parasites dramatically alter the rheological properties of infected red blood cells. In the case of Plasmodium vivax, the parasite rapidly decreases…”
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A new heparan sulfate from the mollusk Nodipecten nodosus inhibits merozoite invasion and disrupts rosetting and cytoadherence of Plasmodium falciparum
Published in Memórias do Instituto Oswaldo Cruz (01-01-2019)“…Despite treatment with effective antimalarial drugs, the mortality rate is still high in severe cases of the disease, highlighting the need to find adjunct…”
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B-cell epitopes in NTS-DBL1α of PfEMP1 recognized by human antibodies in Rosetting Plasmodium falciparum
Published in PloS one (01-12-2014)“…Plasmodium falciparum is the most lethal of the human malaria parasites. The virulence is associated with the capacity of the infected red blood cell (iRBC) to…”
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