Search Results - "ALBERT, Marilyn"
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Reduction of Hippocampal Hyperactivity Improves Cognition in Amnestic Mild Cognitive Impairment
Published in Neuron (Cambridge, Mass.) (10-05-2012)“…Elevated hippocampal activation is observed in conditions that confer risk for Alzheimer's disease, including amnestic mild cognitive impairment (aMCI)…”
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Changes in cognition
Published in Neurobiology of aging (01-12-2011)“…Abstract The clinical hallmark of Alzheimer's disease (AD) is a gradual decline in cognitive function. For the majority of patients the initial symptom is an…”
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Bayesian Parameter Estimation and Segmentation in the Multi-Atlas Random Orbit Model
Published in PloS one (18-06-2013)“…This paper examines the multiple atlas random diffeomorphic orbit model in Computational Anatomy (CA) for parameter estimation and segmentation of subcortical…”
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Hearing loss and dementia - who is listening?
Published in Aging & mental health (01-01-2014)Get full text
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Heart health meets cognitive health: evidence on the role of blood pressure
Published in Lancet neurology (01-10-2021)“…The enormous societal and financial burden of Alzheimer's disease and related dementias requires the identification of risk factors and pathways to reduce…”
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Harmonization of large MRI datasets for the analysis of brain imaging patterns throughout the lifespan
Published in NeuroImage (Orlando, Fla.) (01-03-2020)“…As medical imaging enters its information era and presents rapidly increasing needs for big data analytics, robust pooling and harmonization of imaging data…”
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Associations Between Midlife Vascular Risk Factors and 25-Year Incident Dementia in the Atherosclerosis Risk in Communities (ARIC) Cohort
Published in JAMA neurology (01-10-2017)“…Vascular risk factors have been associated with cognitive decline. Midlife exposure to these factors may be most important in conferring late-life risk of…”
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MRI signatures of brain age and disease over the lifespan based on a deep brain network and 14 468 individuals worldwide
Published in Brain (London, England : 1878) (01-07-2020)“…Deep learning has emerged as a powerful approach to constructing imaging signatures of normal brain ageing as well as of various neuropathological processes…”
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African Americans and Clinical Research: Evidence Concerning Barriers and Facilitators to Participation and Recruitment Recommendations
Published in The Gerontologist (01-04-2017)“…The goal of the study was to examine barriers and facilitators to clinical research participation among African Americans, as well as recommendations for…”
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Hearing impairment and cognitive decline: a pilot study conducted within the atherosclerosis risk in communities neurocognitive study
Published in American journal of epidemiology (01-05-2015)“…Hearing impairment (HI) is prevalent, is modifiable, and has been associated with cognitive decline. We tested the hypothesis that audiometric HI measured in…”
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Hearing intervention versus health education control to reduce cognitive decline in older adults with hearing loss in the USA (ACHIEVE): a multicentre, randomised controlled trial
Published in The Lancet (British edition) (02-09-2023)“…Hearing loss is associated with increased cognitive decline and incident dementia in older adults. We aimed to investigate whether a hearing intervention could…”
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The diagnosis of mild cognitive impairment due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease
Published in Alzheimer's & dementia (01-05-2011)“…Abstract The National Institute on Aging and the Alzheimer’s Association charged a workgroup with the task of developing criteria for the symptomatic…”
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The Association of Late-Life Diabetes Status and Hyperglycemia With Incident Mild Cognitive Impairment and Dementia: The ARIC Study
Published in Diabetes care (01-07-2019)“…We sought to examine associations in older adults among diabetes, glycemic control, diabetes duration, and biomarkers of hyperglycemia with incident mild…”
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Response of the medial temporal lobe network in amnestic mild cognitive impairment to therapeutic intervention assessed by fMRI and memory task performance
Published in NeuroImage clinical (01-01-2015)“…Studies of individuals with amnestic mild cognitive impairment (aMCI) have detected hyperactivity in the hippocampus during task-related functional magnetic…”
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Human Herpesvirus 6 Detection in Alzheimer’s Disease Cases and Controls across Multiple Cohorts
Published in Neuron (Cambridge, Mass.) (18-03-2020)“…The interplay between viral infection and Alzheimer’s disease (AD) has long been an area of interest, but proving causality has been elusive. Several recent…”
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Pattern separation deficits associated with increased hippocampal CA3 and dentate gyrus activity in nondemented older adults
Published in Hippocampus (01-09-2011)“…There is widespread evidence that memory deteriorates with aging, however the exact mechanisms that underlie these changes are not well understood. Given the…”
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The Brain Chart of Aging: Machine‐learning analytics reveals links between brain aging, white matter disease, amyloid burden, and cognition in the iSTAGING consortium of 10,216 harmonized MR scans
Published in Alzheimer's & dementia (01-01-2021)“…Introduction Relationships between brain atrophy patterns of typical aging and Alzheimer's disease (AD), white matter disease, cognition, and AD neuropathology…”
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Introduction to the recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
Published in Alzheimer's & dementia (01-05-2011)“…Abstract Background Criteria for the clinical diagnosis of Alzheimer's disease (AD) were established in 1984. A broad consensus now exists that these criteria…”
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Blood–Brain Barrier Breakdown in Relationship to Alzheimer and Vascular Disease
Published in Annals of neurology (01-08-2021)“…Objective Blood–brain barrier (BBB) breakdown has been suggested to be an early biomarker in human cognitive impairment. However, the relationship between BBB…”
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High-resolution structural and functional MRI of hippocampal CA3 and dentate gyrus in patients with amnestic Mild Cognitive Impairment
Published in NeuroImage (Orlando, Fla.) (01-07-2010)“…Functional magnetic resonance imaging (fMRI) studies have observed hyperactivity in the hippocampal region in individuals with Mild Cognitive Impairment (MCI)…”
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