Search Results - "ALBER, Michael"

Fracture propagation in sandstone and slate – Laboratory experiments, acoustic emissions and fracture mechanics by Ferdinand Stoeckhert, Michael Molenda, Sebastian Brenne, Michael Alber

“…Fracturing of highly anisotropic rocks is a problem often encountered in the stimulation of unconventional hydrocarbon or geothermal reservoirs by hydraulic…”
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Targeted next generation sequencing as a diagnostic tool in epileptic disorders by Lemke, Johannes R., Riesch, Erik, Scheurenbrand, Tim, Schubach, Max, Wilhelm, Christian, Steiner, Isabelle, Hansen, Jörg, Courage, Carolina, Gallati, Sabina, Bürki, Sarah, Strozzi, Susi, Simonetti, Barbara Goeggel, Grunt, Sebastian, Steinlin, Maja, Alber, Michael, Wolff, Markus, Klopstock, Thomas, Prott, Eva C., Lorenz, Rüdiger, Spaich, Christiane, Rona, Sabine, Lakshminarasimhan, Maya, Kröll, Judith, Dorn, Thomas, Krämer, Günter, Synofzik, Matthis, Becker, Felicitas, Weber, Yvonne G., Lerche, Holger, Böhm, Detlef, Biskup, Saskia

“…Summary Purpose:  Epilepsies have a highly heterogeneous background with a strong genetic contribution. The variety of unspecific and overlapping syndromic and…”
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Rock mechanical analysis of a Ml= 4.0 seismic event induced by mining in the Saar District, Germany by Alber, Michael, Fritschen, Ralf

“…SUMMARY On 2008 February 23 a 4.0 magnitude seismic event occurred in close proximity to a deep underground longwall coal mine in the German Saar mining…”
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A Novel, Apparently Silent Variant in MFSD8 Causes Neuronal Ceroid Lipofuscinosis with Marked Intrafamilial Variability by Reith, Milda, Zeltner, Lena, Schäferhoff, Karin, Witt, Dennis, Zuleger, Theresia, Haack, Tobias B, Bornemann, Antje, Alber, Michael, Ruf, Susanne, Schoels, Ludger, Stingl, Katarina, Weisschuh, Nicole

“…Variants in can cause neuronal ceroid lipofuscinoses (NCLs) as well as nonsyndromic retinopathy. The mutation spectrum includes mainly missense and stop…”
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Functional correlates of clinical phenotype and severity in recurrent SCN2A variants by Berecki, Géza, Howell, Katherine B., Heighway, Jacqueline, Olivier, Nelson, Rodda, Jill, Overmars, Isabella, Vlaskamp, Danique R. M., Ware, Tyson L., Ardern-Holmes, Simone, Lesca, Gaetan, Alber, Michael, Veggiotti, Pierangelo, Scheffer, Ingrid E., Berkovic, Samuel F., Wolff, Markus, Petrou, Steven

“…In SCN2A- related disorders, there is an urgent demand to establish efficient methods for determining the gain- (GoF) or loss-of-function (LoF) character of…”
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ISRM Suggested Method for Determining the Abrasivity of Rock by the CERCHAR Abrasivity Test by ALBER, Michael, YARALI, Olgay, DAHL, Filip, BRULAND, Amund, KÄSLING, Heiko, MICHALAKOPOULOS, Theodore N, CARDU, Marilena, HAGAN, Paul, AYDIN, Hamit, ÖZARSLAN, Ahmet

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Stress dependency of the Cerchar abrasivity index (CAI) and its effects on wear of selected rock cutting tools by Alber, Michael

“…The abrasiveness of rocks is often described by the Cerchar abrasivity index CAI. However, the state of stress of the rock sample with the standard CAI test in…”
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Tectonic conditioning revealed by seismic refraction facilitates deep-seated landslides in the western escarpment of the Main Ethiopian Rift by Mebrahtu, Tesfay Kiros, Alber, Michael, Wohnlich, Stefan

“…Landslide is a geo-hazard phenomenon that has been taking lives and causing severe property damages all over the world mostly in mountainous areas. The Main…”
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Slope stability analysis of deep-seated landslides using limit equilibrium and finite element methods in Debre Sina area, Ethiopia by Mebrahtu, Tesfay Kiros, Heinze, Thomas, Wohnlich, Stefan, Alber, Michael

“…Slope failure is a recurring natural hazard in the western margin of the Main Ethiopian Rift and especially around the Debre Sina area. To minimize the damage…”
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Erfahrungen zur Festigkeitsbestimmung von Mergelgesteinen mit dem Nadelpenetrometer by Aderhold, Moritz, Alber, Michael, Plinninger, Ralf J.

“…Die zutreffende Beurteilung der einaxialen Druckfestigkeit stellt eine der Kernaufgaben der Geotechnik im Kontext der Planung und Ausführung von Tief‐, Tunnel‐…”
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Electrical impedance spectroscopy measurements to estimate the uniaxial compressive strength of a fault breccia by Kahraman, Sair, Alber, Michael

“…Fault breccias are usually not suitable for preparing smooth specimens or else the preparation of such specimens is tedious, time consuming and expensive. To…”
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Efficacy, tolerability, and retention of fenfluramine for the treatment of seizures in patients with Dravet syndrome: Compassionate use program in Germany by Strzelczyk, Adam, Pringsheim, Milka, Mayer, Thomas, Polster, Tilman, Klotz, Kerstin A., Muhle, Hiltrud, Alber, Michael, Trollmann, Regina, Spors, Hartwig, Kluger, Gerhard, Kurlemann, Gerhard, Schubert‐Bast, Susanne

“…Objective Dravet syndrome (DS) is a rare but severe drug‐resistant epilepsy. Before the approval of fenfluramine (FFA) for the treatment of seizures in DS,…”
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The phenotype of SCN8A developmental and epileptic encephalopathy by Gardella, Elena, Marini, Carla, Trivisano, Marina, Fitzgerald, Mark P, Alber, Michael, Howell, Katherine B, Darra, Francesca, Siliquini, Sabrina, Bölsterli, Bigna K, Masnada, Silva, Pichiecchio, Anna, Johannesen, Katrine M, Jepsen, Birgit, Fontana, Elena, Anibaldi, Gaia, Russo, Silvia, Cogliati, Francesca, Montomoli, Martino, Specchio, Nicola, Rubboli, Guido, Veggiotti, Pierangelo, Beniczky, Sandor, Wolff, Markus, Helbig, Ingo, Vigevano, Federico, Scheffer, Ingrid E, Guerrini, Renzo, Møller, Rikke S

“…OBJECTIVETo delineate the electroclinical features of SCN8A infantile developmental and epileptic encephalopathy (EIEE13, OMIM #614558). METHODSTwenty-two…”
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Long-term clinical course and treatment outcomes of individuals with Nodding Syndrome by Kegele, Josua, Wagner, Thomas, Kowenski, Teresa, Wiesmayr, Matthias, Gatterer, Christian, Alber, Michael, Matuja, Wiliam, Schmutzhard, Erich, Lerche, Holger, Winkler, Andrea S.

“…Nodding Syndrome is a poorly understood epilepsy disorder in sub-Saharan Africa. The cause(s) of the disease, risk factors and long-term outcomes are unknown…”
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Mutations in GRIN2A cause idiopathic focal epilepsy with rolandic spikes by Lemke, Johannes R, Lal, Dennis, Reinthaler, Eva M, Steiner, Isabelle, Nothnagel, Michael, Alber, Michael, Geider, Kirsten, Laube, Bodo, Schwake, Michael, Finsterwalder, Katrin, Franke, Andre, Schilhabel, Markus, Jähn, Johanna A, Muhle, Hiltrud, Boor, Rainer, Van Paesschen, Wim, Caraballo, Roberto, Fejerman, Natalio, Weckhuysen, Sarah, De Jonghe, Peter, Larsen, Jan, Møller, Rikke S, Hjalgrim, Helle, Addis, Laura, Tang, Shan, Hughes, Elaine, Pal, Deb K, Veri, Kadi, Vaher, Ulvi, Talvik, Tiina, Dimova, Petia, Guerrero López, Rosa, Serratosa, José M, Linnankivi, Tarja, Lehesjoki, Anna-Elina, Ruf, Susanne, Wolff, Markus, Buerki, Sarah, Wohlrab, Gabriele, Kroell, Judith, Datta, Alexandre N, Fiedler, Barbara, Kurlemann, Gerhard, Kluger, Gerhard, Hahn, Andreas, Haberlandt, D Edda, Kutzer, Christina, Sperner, Jürgen, Becker, Felicitas, Weber, Yvonne G, Feucht, Martha, Steinböck, Hannelore, Neophythou, Birgit, Ronen, Gabriel M, Gruber-Sedlmayr, Ursula, Geldner, Julia, Harvey, Robert J, Hoffmann, Per, Herms, Stefan, Altmüller, Janine, Toliat, Mohammad R, Thiele, Holger, Nürnberg, Peter, Wilhelm, Christian, Stephani, Ulrich, Helbig, Ingo, Lerche, Holger, Zimprich, Fritz, Neubauer, Bernd A, Biskup, Saskia, von Spiczak, Sarah

“…Sarah von Spiczak, Holger Lerche and colleagues identify mutations in GRIN2A that cause idiopathic focal epilepsy with rolandic spikes. Idiopathic focal…”
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Cenobamate: real-world data from a retrospective multicenter study by Lauxmann, Stephan, Heuer, David, Heckelmann, Jan, Fischer, Florian P., Schreiber, Melanie, Schriewer, Elisabeth, Widman, Guido, Weber, Yvonne, Lerche, Holger, Alber, Michael, Schuh-Hofer, Sigrid, Wolking, Stefan

“…Background Clinical trials have shown that cenobamate (CNB) is an efficacious and safe anti-seizure medication (ASM) for drug-resistant focal epilepsy. Here,…”
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Correction to: Cenobamate: real-world data from a retrospective multicenter study by Lauxmann, Stephan, Heuer, David, Heckelmann, Jan, Fischer, Florian P., Schreiber, Melanie, Schriewer, Elisabeth, Widman, Guido, Weber, Yvonne, Lerche, Holger, Alber, Michael, Schuh-Hofer, Sigrid, Wolking, Stefan

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Influence of the slurry-stabilized tunnel face on shield TBM tool wear regarding the soil mechanical changes – Experimental evidence of changes in the tribological system by Küpferle, Jakob, Zizka, Zdenek, Schoesser, Britta, Röttger, Arne, Alber, Michael, Thewes, Markus, Theisen, Werner

“…The wear of slurry shield TBM excavation tools is a challenging topic that has been discussed over many years, Due to the complexity of the tribological system…”
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Rock mechanical analysis of a Ml= 4.0 seismic event induced by mining in the Saar District, Germany: Ml= 4.0 seismic event induced by mining by Alber, Michael, Fritschen, Ralf

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KCTD7 deficiency defines a distinct neurodegenerative disorder with a conserved autophagy‐lysosome defect by Metz, Kyle A., Teng, Xinchen, Coppens, Isabelle, Lamb, Heather M., Wagner, Bart E., Rosenfeld, Jill A., Chen, Xianghui, Zhang, Yu, Kim, Hee Jong, Meadow, Michael E., Wang, Tim Sen, Haberlandt, Edda D., Anderson, Glenn W., Leshinsky‐Silver, Esther, Bi, Weimin, Markello, Thomas C., Pratt, Marsha, Makhseed, Nawal, Garnica, Adolfo, Danylchuk, Noelle R., Burrow, Thomas A., Jayakar, Parul, McKnight, Dianalee, Agadi, Satish, Gbedawo, Hatha, Stanley, Christine, Alber, Michael, Prehl, Isabelle, Peariso, Katrina, Ong, Min Tsui, Mordekar, Santosh R., Parker, Michael J., Crooks, Daniel, Agrawal, Pankaj B., Berry, Gerard T., Loddenkemper, Tobias, Yang, Yaping, Maegawa, Gustavo H. B., Aouacheria, Abdel, Markle, Janet G., Wohlschlegel, James A., Hartman, Adam L., Hardwick, J. Marie

“…Objective Several small case series identified KCTD7 mutations in patients with a rare autosomal recessive disorder designated progressive myoclonic epilepsy…”
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